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5,8-Dideazapteroylornithine

5,8-Dideazapteroylornithine structure

CAS No.: 118675-83-5

Chemical Name:: 5,8-Dideazapteroylornithine

Synonyms: DDPO;8-Dideazapteroylornithine;5,8-Dideazapteroylornithine;L-Ornithine, N2-[4-[[(2-amino-1,4-dihydro-4-oxo-6-quinazolinyl)methyl]amino]benzoyl]- (9CI)

CBNumber:: CB81243512

Molecular Formula:: C21H24N6O4

Molecular Weight:: 424.45

MDL Number:

MOL File:: 118675-83-5.mol

MSDS File:: SDS

Last updated:2026-05-11 19:39:08

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5,8-Dideazapteroylornithine Chemical Properties, Uses, Production

Description

DDPO is a folypolyglutamate synthetase antagonist.

Uses

DDPO is an inhibitor for dihydrofolate reductase (DHFR) with an IC50 of 0.035 μM. DDPO inhibits the cell growth of cancer cell L1210 and WI-L2with IC50 of 5 and 0.28 μM[1].

References

[1] Rosowsky A, et al., Synthesis and in vitro biological activity of new deaza analogues of folic acid, aminopterin, and methotrexate with an L-ornithine side chain.

5,8-Dideazapteroylornithine Preparation Products And Raw materials

Raw materials

Preparation Products

5,8-Dideazapteroylornithine Suppliers

Global Suppliers ( 4)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Latest Price from 5,8-Dideazapteroylornithine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	DDPO 118675-83-5	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

DDPO
118675-83-5
$1520.00-2500.00
TargetMol Chemicals Inc.

118675-83-5 (5,8-Dideazapteroylornithine) Related Search:

CB 3705 10-formyldihydrofolate 4-[N-(2,4-Diamino-6-pteridinylmethyl)-N-methylamino] benzoic acid Piritrexim 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-[(2-fluoro-4-pyridinyl)methyl]-

DAMPA Methyl Ester

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5,8-Dideazapteroylornithine L-Ornithine, N2-[4-[[(2-amino-1,4-dihydro-4-oxo-6-quinazolinyl)methyl]amino]benzoyl]- (9CI) 8-Dideazapteroylornithine DDPO 118675-83-5