songorine
- CAS No.
- 509-24-0
- Chemical Name:
- songorine
- Synonyms
- Bullatine;Songorin;Zongorine;Xuan-Wu 2;Napellonin;Napellonine;product/155133;ShiMoburo base I;Songorine,BullatineG;Bullatine G Songorine
- CBNumber:
- CB81361634
- Molecular Formula:
- C22H31NO3
- Molecular Weight:
- 357.49
- MDL Number:
- MFCD04037233
- MOL File:
- 509-24-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 201-203℃ |
|---|---|
| alpha | D20 -135.4° |
| Boiling point | 535.8±50.0 °C(Predicted) |
| Density | 1.29 |
| solubility | DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 5 mg/ml; Ethanol: slightly soluble |
| form | A solid |
| pka | 14.20±0.60(Predicted) |
| color | White to off-white |
| FDA UNII | 64E5D8C741 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H310-H300-H330 | |||||||||
| Precautionary statements | P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501 | |||||||||
| Toxicity | LD50 in mice (mg/kg): 1575 orally, 630 s.c., 485 i.p., 142.5 i.v.; in rats (mg/kg): 407.5 i.p. (Bisset) | |||||||||
| NFPA 704 |
|
songorine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 34601 | Songorine ≥98% | 509-24-0 | 1mg | $54 | 2026-04-30 | Buy |
| Cayman Chemical | 34601 | Songorine ≥98% | 509-24-0 | 5mg | $172 | 2026-04-30 | Buy |
| Cayman Chemical | 34601 | Songorine ≥98% | 509-24-0 | 10mg | $315 | 2026-04-30 | Buy |
| Cayman Chemical | 34601 | Songorine ≥98% | 509-24-0 | 25mg | $717 | 2026-04-30 | Buy |
| Usbiological | 300032 | Bullatine G (Songorin, Songorine, Napellonine) ≥98% | 509-24-0 | 10mg | $433 | 2026-06-03 | Buy |
songorine Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Chuanwu and Aconitum.
Uses
Songorine is an extract from the Aconitum flavum root and may act as an inhibitor of JNK and p53 enhancing stimulation of fibroblast colony/cluster formation and proliferative activity of mesosomal precursors.
in vivo
Songorine is investigated its efficacy and safety in SKOV3 tumorbearing BALB/c nude mice, songorineinhibits EOC cell survival, invasion and migration, promoted EOC cell apoptosis and suppressed mammalian EOC tumorigenic behavior. In addition, western blot and IHC results show that songorine consistently downregulates the expression of Ncadherin, vimentin, matrix metalloproteinase (MMP)2, MMP9, phosphorylated GSK3β, βcatenin and Bcl2, and upregulated the expression of Ecadherin, cleaved caspase3, cleaved caspase9 and Bax[1]. Songorine shows an Antiarrhythmic activity in aconitine-induced arrhythmia model in rats, exhibits LD50 and ED50 values of 142 mg and 7.3mg, respectively[2].
songorine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Winherb Medical Technology Co., Ltd. | 17301719108 13341702378 | winherb@126.com | China | 1245 | 58 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| ALB Technology Limited | 702-983-3769 | sales@albtechnology.com | United States | 2992 | 55 |
View Lastest Price from songorine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Songorine
509-24-0
|
$64.00-195.00 | 98.97% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Songorine
509-24-0
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | ||
 |
2019-12-31 | songorine
509-24-0
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
