5-Bromo-6-hydroxynicotinic acid
- CAS No.
- 41668-13-7
- Chemical Name:
- 5-Bromo-6-hydroxynicotinic acid
- Synonyms
- 5-BROMO-6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID;5-Bromo-6-Hydroxy Niacin;6-Hydroxy-5-bromonicotinic acid;5-Bromo-6-hydroxynicotinic acid;3-BROMO-5-CARBOXY-2(1H)-PYRIDINONE;5-Bromo-6-hydroxynicotinic acid 97%;5-Bromo-6-hydroxynicotinic acid ,97%;5-bromo-6-oxo-1H-pyridine-3-carboxylic acid;5-BROMO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;5-Bromo-6-hydroxy-pyridin-3-carboxylic acid
- CBNumber:
- CB8137629
- Molecular Formula:
- C6H4BrNO3
- Molecular Weight:
- 218
- MDL Number:
- MFCD08235173
- MOL File:
- 41668-13-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | >300 |
|---|---|
| Boiling point | 348.1±42.0 °C(Predicted) |
| Density | 2.015±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 3.38±0.50(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C6H4BrNO3/c7-4-1-3(6(10)11)2-8-5(4)9/h1-2H,(H,8,9)(H,10,11) |
| InChIKey | PQDLYKZCJBGXPQ-UHFFFAOYSA-N |
| SMILES | C1NC(=O)C(Br)=CC=1C(O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Hazard Note | Irritant/Keep Cold | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
5-Bromo-6-hydroxynicotinic acid price More Price(83)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B5193 | 5-Bromo-6-hydroxynicotinic Acid >98.0%(GC)(T) | 41668-13-7 | 1g | $57 | 2026-04-30 | Buy |
| TCI Chemical | B5193 | 5-Bromo-6-hydroxynicotinic Acid >98.0%(GC)(T) | 41668-13-7 | 5g | $171 | 2026-04-30 | Buy |
| AstaTech | CL0229 | 5-BROMO-6-HYDROXYNICOTINICACID 97% | 41668-13-7 | 25G | $44 | 2026-04-30 | Buy |
| AK Scientific | R459 | 5-Bromo-6-hydroxynicotinic acid 98%(HPLC) | 41668-13-7 | 5g | $18 | 2026-06-04 | Buy |
| AK Scientific | R459 | 5-Bromo-6-hydroxynicotinic acid 98%(HPLC) | 41668-13-7 | 25g | $66 | 2026-06-04 | Buy |
5-Bromo-6-hydroxynicotinic acid Chemical Properties, Uses, Production
Chemical Properties
Light green solid
Synthesis
5006-66-6
41668-13-7
Synthesis of 5-bromo-6-hydroxynicotinic acid: 6-hydroxynicotinic acid (8 g, 57.6 mmol) was suspended in water (30 mL) and bromine (4.2 mL, 81.4 mmol) was slowly added under ice bath cooling conditions. After addition, the reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the solid product was collected by filtration, washed with water and dried in a vacuum oven at 40 °C for 24 h to afford 5-bromo-6-hydroxynicotinic acid (12.1 g, 97% yield) as a tan solid. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.04 (d, J = 2.53 Hz, 1H), 8.16 (d, J = 2.27 Hz, 1H), 12.59 (br s, 1H), 12.90 (br s, 1H).
References
[1] Journal of Medicinal Chemistry, 2013, vol. 56, # 24, p. 9874 - 9896
[2] Journal of Medicinal Chemistry, 2005, vol. 48, # 15, p. 4892 - 4909
[3] Patent: WO2007/70818, 2007, A1. Location in patent: Page/Page column 103
[4] Patent: WO2006/88919, 2006, A2. Location in patent: Page/Page column 134-135
[5] Patent: US2008/85906, 2008, A1. Location in patent: Page/Page column 15
5-Bromo-6-hydroxynicotinic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Carlow Chemicals Co., Ltd. | 21-33526724 18930996265 | info@carlowchem.com | China | 1996 | 58 |
| Sanjing New Materials Technology (Taizhou) Co., Ltd. | 13852622638 | 1048979734@qq.com | China | 778 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 |
View Latest Price from 5-Bromo-6-hydroxynicotinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 5-BROMO-6-HYDROXYNICOTINIC ACID
41668-13-7
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 5-BROMO-6-HYDROXYNICOTINIC ACID
41668-13-7
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-06-30 | 5-BROMO-6-HYDROXYNICOTINIC ACID
41668-13-7
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 5-BROMO-6-HYDROXYNICOTINIC ACID
41668-13-7
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 5-BROMO-6-HYDROXYNICOTINIC ACID
41668-13-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-BROMO-6-HYDROXYNICOTINIC ACID
41668-13-7
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
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