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1,2,3,4-Tetrahydroquinolin-6-ol

1,2,3,4-Tetrahydroquinolin-6-ol structure

CAS No.: 3373-00-0

Chemical Name:: 1,2,3,4-Tetrahydroquinolin-6-ol

Synonyms: 1,2,3,4-Tetrahydro-6-quinolinol;4-TETRAHYDROQUINOLIN-6-OL;1,2,3,4-Tetrahydroquinolin-6-ol;1,2,3,4-Tetrahydroquinoline-6-ol;6-Quinolinol, 1,2,3,4-tetrahydro-;5-hydroxy-1,2,3,4-Tetrahydro-quinolin;6-hydroxy-1,2,3,4-Tetrahydro-quinolin;6-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE;1,2,3,4-tetrahydroquinolin-6-ol hydrochloride;1,2,3,4-TETRAHYDROQUINOLIN-6-OL ISO 9001：2015 REACH

CBNumber:: CB4756109

Molecular Formula:: C9H11NO

Molecular Weight:: 149.19

MDL Number:: MFCD00800243

MOL File:: 3373-00-0.mol

MSDS File:: SDS

Last updated:2026-09-12 18:52:57

Request For Quotation

1,2,3,4-Tetrahydroquinolin-6-ol Properties

Melting point	160 °C
Boiling point	337.5±31.0 °C(Predicted)
Density	1.141±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Methanol
form	Solid
pka	11.48±0.20(Predicted)
color	Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2933499090

1,2,3,4-Tetrahydroquinolin-6-ol price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR912575	1,2,3,4-Tetrahydroquinolin-6-ol >97%	3373-00-0	1g	$21	2026-06-04	Buy
Apolloscientific	OR912575	1,2,3,4-Tetrahydroquinolin-6-ol >97%	3373-00-0	5g	$63	2026-06-04	Buy
Apolloscientific	OR912575	1,2,3,4-Tetrahydroquinolin-6-ol >97%	3373-00-0	25g	$311	2026-06-04	Buy
Apolloscientific	OR912575	1,2,3,4-Tetrahydroquinolin-6-ol >97%	3373-00-0	100g	$1237	2026-06-04	Buy
Synthonix	H50028	6-Hydroxy-1,2,3,4-tetrahydroquinoline 95%	3373-00-0	250mg	$17	2026-05-06	Buy

Product number	Packaging	Price	Buy
OR912575	1g	$21	Buy
OR912575	5g	$63	Buy
OR912575	25g	$311	Buy
OR912575	100g	$1237	Buy
H50028	250mg	$17	Buy

1,2,3,4-Tetrahydroquinolin-6-ol Chemical Properties, Uses, Production

Chemical Properties

Off-White Solid

Uses

A potential amoebicide.

Synthesis

120-15-0

3373-00-0

General procedure for the synthesis of 6-hydroxy-1,2,3,4-tetrahydroquinoline from 6-methoxy-1,2,3,4-tetrahydroquinoline: 6-methoxy-1,2,3,4-tetrahydroquinoline (3.00 g, 18.38 mmol) was dissolved in 50 mL of dichloromethane, and boron tribromide (13.81 g, 55.14 mmol) was slowly added at 0 °C. The reaction system was then warmed up to 15 °C with continuous stirring for 2 hours. After completion of the reaction, the reaction solution was concentrated and the reaction was quenched with 5 mL of methanol. To the reaction mixture, 20 mL of saturated sodium bicarbonate solution was added and stirred for 30 minutes. The reaction was extracted three times with 20 mL of ethyl acetate, the organic phases were combined and dried with anhydrous sodium sulfate. The organic phase was concentrated to give the crude product. The crude product was purified by silica gel column chromatography (eluent ratio: petroleum ether/ethyl acetate from 3:1 to 1:1 gradient elution) to finally obtain 6-hydroxy-1,2,3,4-tetrahydroquinoline (1.95 g, yield 71.11%). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.24 (s, 1H), 6.22-6.35 (m, 3H), 4.93 (br.s, 1H), 3.02-3.10 (m, 2H), 2.57 (t, J = 6.4 Hz, 2H), 1.67-1.80 (m, 2H).

References

[1] Patent: EP3293177, 2018, A1. Location in patent: Paragraph 0222; 0224
[2] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 13, p. 3415 - 3418

1,2,3,4-Tetrahydroquinolin-6-ol Preparation Products And Raw materials

Raw materials

6-Methoxy-1,2,3,4-tetrahydroquinoline Boron tribromide Dichloromethane

Preparation Products

Quinfamide 6-Quinolinol

1,2,3,4-Tetrahydroquinolin-6-ol Suppliers

Global Suppliers ( 124)

Supplier	Tel	Email	Country	ProdList	Advantage
Shandong Xuande Pharmaceutical Technology Co. LTD	18866895588	dingjiaying@shiningpharm.com	China	184	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
China DongFan Chemical Co.,LTD	86-0571-85151182		China	5681	66
Shanghai Topbiochem Technology Co., Ltd	021-58170097	info@topbiochem.com	China	9509	58
Runpharm Technology Limited	18171398856 2968382473	service@runpharm.com	China	716	55

Supplier	Advantage
Shandong Xuande Pharmaceutical Technology Co. LTD	55
J & K SCIENTIFIC LTD.	76
Energy Chemical	61
Capot Chemical Co., Ltd	66
Accela ChemBio Co.,Ltd.	64
Shanghai Longsheng chemical Co.,Ltd.	59
Chemsky（shanghai）International Co.,Ltd.	50
China DongFan Chemical Co.,LTD	66
Shanghai Topbiochem Technology Co., Ltd	58
Runpharm Technology Limited	55

View Latest Price from 1,2,3,4-Tetrahydroquinolin-6-ol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	1,2,3,4-TETRAHYDROQUINOLIN-6-OL 3373-00-0	$1.00-50.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2025-04-04	1,2,3,4-TETRAHYDROQUINOLIN-6-OL 3373-00-0		1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.
2020-03-06	1,2,3,4-TETRAHYDROQUINOLIN-6-OL 3373-00-0	$1.00	1KG	99%	200kgs	Career Henan Chemical Co

1,2,3,4-TETRAHYDROQUINOLIN-6-OL
3373-00-0
$1.00-50.00
99%
Henan Fengda Chemical Co., Ltd

1,2,3,4-TETRAHYDROQUINOLIN-6-OL
3373-00-0
98%
Henan Aochuang Chemical Co.,Ltd.

1,2,3,4-TETRAHYDROQUINOLIN-6-OL
3373-00-0
$1.00
99%
Career Henan Chemical Co

1,2,3,4-Tetrahydroquinolin-6-ol Spectrum

1,2,3,4-TETRAHYDROQUINOLIN-6-OL(3373-00-0)¹HNMR

3373-00-0 (1,2,3,4-Tetrahydroquinolin-6-ol) Related Search:

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6-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE 1,2,3,4-Tetrahydroquinoline-6-ol 6-hydroxy-1,2,3,4-Tetrahydro-quinolin 5-hydroxy-1,2,3,4-Tetrahydro-quinolin 1,2,3,4-tetrahydroquinolin-6-ol hydrochloride 6-Quinolinol, 1,2,3,4-tetrahydro- 1,2,3,4-TETRAHYDROQUINOLIN-6-OL ISO 9001：2015 REACH 4-TETRAHYDROQUINOLIN-6-OL 1,2,3,4-Tetrahydro-6-quinolinol 1,2,3,4-Tetrahydroquinolin-6-ol 3373-00-0 Aromatics Heterocycles Quinolines, Quinazolines and derivatives pharmacetical