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BMS-1233

BMS-1233 structure

CAS No.: 2447065-99-6

Chemical Name:: BMS-1233

Synonyms: BMS-1233;2-Piperidinecarboxylic acid, 1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[(2-methyl[1,1′-biphenyl]-3-yl)methoxy]phenyl]methyl]-

CBNumber:: CB813770965

Molecular Formula:: C35H33ClN2O4

Molecular Weight:: 581.1

MDL Number:

MOL File:: 2447065-99-6.mol

MSDS File:: SDS

Last updated:2025-05-19 13:47:28

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BMS-1233 Properties

Boiling point	738.012±60.00 °C(Press: 760.00 Torr)(predicted)
Density	1.311±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	2.330±0.20(predicted)

BMS-1233 Chemical Properties, Uses, Production

Uses

BMS-1233 is an orally active inhibitor for programmed cell death-ligand 1 (PD-L1), with IC50 of 14.5 nM. BMS-1233 promotes cell death of HepG2 in a Jurkat T cell and HepG2 cell co-culture model, exhibits antitumor activity against melanoma in mouse model[1].

References

[1] Cheng B, et al., Bifunctional small molecules targeting PD-L1/CXCL12 as dual immunotherapy for cancer treatment. Signal Transduct Target Ther. 2023 Mar 1;8(1):91. DOI:10.1038/s41392-022-01292-5

BMS-1233 Preparation Products And Raw materials

Raw materials

Preparation Products

BMS-1233 Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	4999	58
InvivoChem	13549236410	sales@invivochem.cn	China	6745	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Jinan Jiuli Biotechnology Co. , Ltd.	58
InvivoChem	58
TargetMol Chemicals Inc.	58

2447065-99-6 (BMS-1233) Related Search:

2-Piperidinecarboxylic acid, 1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl]- 2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)- BMS-1166 BMS-1233 Alanine, N-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-2-methyl-

BMS-1166 HCl

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BMS-1233 2-Piperidinecarboxylic acid, 1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[(2-methyl[1,1′-biphenyl]-3-yl)methoxy]phenyl]methyl]- 2447065-99-6