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GR 64349

GR 64349 structure

CAS No.: 137593-52-3

Chemical Name:: GR 64349

Synonyms: GR 64349;GR-64349 (GR64349);LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2;[LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10);L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-L-methioninamide;L-Methioninamide,L-lysyl-L-a-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(aS,3R)-3-amino-a-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-;L-Methioninamide, L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-;L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidinyl]-NH2

CBNumber:: CB8138196

Molecular Formula:: C42H68N10O11S

Molecular Weight:: 921.11

MDL Number:: MFCD00153800

MOL File:: 137593-52-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:37

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GR 64349 Properties

Boiling point	1342.8±65.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	Soluble to 1 mg/ml in 20% ethanol / water
form	Powder
pka	4.13±0.10(Predicted)
color	White to off-white
Water Solubility	Soluble to 1 mg/ml in water
Sequence	Lys-Asp-Ser-Phe-Val-{Aaa}-Leu-Met-NH2
InChIKey	HVUNRXRFMQDMBO-NOJSRKIXSA-N
SMILES	CSCC[C@H](NC(=O)[C@H](CC(C)C)N1CC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)C1=O)C(N)=O
UNSPSC Code	12352202
NACRES	NA.32

SAFETY

Risk and Safety Statements

PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
Storage Class	11 - Combustible Solids

GR 64349 price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	G113	GR 64349 >96%	137593-52-3	1mg	$941	2026-04-30	Buy
Biosynth	MFA59352	GR 64349	137593-52-3	1mg	$1198.23	2026-06-04	Buy
Biosynth	MFA59352	GR 64349	137593-52-3	5mg	$3386.3	2026-06-04	Buy
Biosynth	MFA59352	GR 64349	137593-52-3	10mg	$5418.1	2026-06-04	Buy
Biosynth	MFA59352	GR 64349	137593-52-3	25mg	$10159	2026-06-04	Buy

Product number	Packaging	Price	Buy
G113	1mg	$941	Buy
MFA59352	1mg	$1198.23	Buy
MFA59352	5mg	$3386.3	Buy
MFA59352	10mg	$5418.1	Buy
MFA59352	25mg	$10159	Buy

GR 64349 Chemical Properties, Uses, Production

Uses

GR 64349 acts as a potent and selective agonist at the NK-2 tachykinin receptor. Initiates changes in the colon, intestine and spinal cord.

Biological Activity

GR 64349 peptide acts as an agonist of neurokinin (NK2) receptor, which leads to reduced NK2 response to kainate and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), but not to NMDA (N-methyl-D-aspartate).

storage

Store at -20°C

GR 64349 synthesis

Synthesis of GR 64349 from Boc-freidinger's lactam

GR 64349 Preparation Products And Raw materials

Raw materials

Preparation Products

GR 64349 Suppliers

Global Suppliers ( 42)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Creative Peptides		info@creative-peptides.com	United States	6083	56
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6288	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
Hangzhou Go Top Peptide Biotech	0571-88211921 17357109671	sales3@gotopbio.com	China	2988	58
Shaoxing Junyu Biotechnology Co., LTD	0571-0571-88211921 19105816207	sales4@gotopbio.com	China	5135	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Nanjing Chemlin Chemical Co., Ltd	64
Chemsky（shanghai）International Co.,Ltd.	50
Creative Peptides	56
Hangzhou Peptidego Biotech Co.,Ltd.	58
BOC Sciences	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Career Henan Chemica Co	58
Hangzhou Go Top Peptide Biotech	58
Shaoxing Junyu Biotechnology Co., LTD	58

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GR 64349 N-Isopropyl-2-pyrrolidone (R)-2-(2-Oxo-pyrrolidin-1-yl)-butyramide 1-Methylpyrrolidin-3-amine 3-Amino-1-methylpyrrolidin-2-one

3-(Ethylamino)pyrrolidine Neurokinin a (4-10) NEUROKININ A

1of4

L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidinyl]-NH2 L-Methioninamide,L-lysyl-L-a-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(aS,3R)-3-amino-a-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl- LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2 [LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10) GR 64349 L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-L-methioninamide GR-64349 (GR64349) L-Methioninamide, L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl- 137593-52-3 C42H68N10O11S Agonist BioChemical Amino Acids and Peptides Biochemicals and Reagents Peptides Tachykinins AgonistPeptides for Cell Biology Neuropeptides Peptides for Cell Biology Tachykinins