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HSD17B13-IN-7

CAS No.
863564-16-3
Chemical Name:
HSD17B13-IN-7
Synonyms
HSD17B13-IN-7;Benzamide, 3-fluoro-4-hydroxy-N-[[trans-1-hydroxy-4-(phenoxymethyl)cyclohexyl]methyl]-
CBNumber:
CB813898461
Molecular Formula:
C21H24FNO4
Molecular Weight:
373.42
MDL Number:
MOL File:
863564-16-3.mol
Last updated:2025-04-18 09:52:49

HSD17B13-IN-7 Properties

Boiling point 551.4±40.0 °C(predicted)
Density 1.245±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 7.30±0.20(predicted)

HSD17B13-IN-7 Chemical Properties, Uses, Production

Uses

HSD17B13-IN-7 (compound 1), a fluorophenol-containing compound, is a potent HSD17B13 inhibitor with IC50s of 0.18 μM and 0.25 μM β-estradiol and Leukotriene B4 as substrates, respectively. HSD17B13-IN-7 is a potent N-methyl-D-aspartate (NMDA) NR2B receptor antagonist. HSD17B13-IN-7 has the potential for non-alcoholic fatty liver disease research[1].

IC 50

NR2B

References

[1] Shenping Liu, et al. Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun. 2023 Aug 24;14(1):5158. DOI:10.1038/s41467-023-40766-0

HSD17B13-IN-7 Preparation Products And Raw materials

Raw materials

Preparation Products

HSD17B13-IN-7 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58

863564-16-3 (HSD17B13-IN-7) Related Search:

HSD17B13-IN-7 Benzamide, 3-fluoro-4-hydroxy-N-[[trans-1-hydroxy-4-(phenoxymethyl)cyclohexyl]methyl]- 863564-16-3