HSD17B13-IN-7
- CAS No.
- 863564-16-3
- Chemical Name:
- HSD17B13-IN-7
- Synonyms
- HSD17B13-IN-7;Benzamide, 3-fluoro-4-hydroxy-N-[[trans-1-hydroxy-4-(phenoxymethyl)cyclohexyl]methyl]-
- CBNumber:
- CB813898461
- Molecular Formula:
- C21H24FNO4
- Molecular Weight:
- 373.42
- MDL Number:
- MOL File:
- 863564-16-3.mol
HSD17B13-IN-7 Chemical Properties, Uses, Production
Uses
HSD17B13-IN-7 (compound 1), a fluorophenol-containing compound, is a potent HSD17B13 inhibitor with IC50s of 0.18 μM and 0.25 μM β-estradiol and Leukotriene B4 as substrates, respectively. HSD17B13-IN-7 is a potent N-methyl-D-aspartate (NMDA) NR2B receptor antagonist. HSD17B13-IN-7 has the potential for non-alcoholic fatty liver disease research[1].
IC 50
NR2B
References
[1] Shenping Liu, et al. Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun. 2023 Aug 24;14(1):5158. DOI:10.1038/s41467-023-40766-0
HSD17B13-IN-7 Preparation Products And Raw materials
Raw materials
Preparation Products
HSD17B13-IN-7 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |




