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TEAD-IN-10

TEAD-IN-10 structure

CAS No.: 3032196-65-6

Chemical Name:: TEAD-IN-10

Synonyms: TEAD-IN-10;2-Propen-1-one, 1-[3-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1-azetidinyl]-

CBNumber:: CB814293265

Molecular Formula:: C15H14F3NO

Molecular Weight:: 281.27

MDL Number:

MOL File:: 3032196-65-6.mol

Last updated:2025-04-17 18:22:24

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TEAD-IN-10 Properties

Boiling point	387.0±42.0 °C(predicted)
Density	1.299±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	-1.68±0.40(predicted)

TEAD-IN-10 Chemical Properties, Uses, Production

Uses

TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research[1].

IC 50

TAED1: 14 nM (IC₅₀); TAED2: 179 nM (IC₅₀); TAED3: 4 nM (IC₅₀)

References

[1] Henry William, et al. Yap/taz-tead oncoproteins inhibitors.WO2024059317A1.2023-09-15

TEAD-IN-10 Preparation Products And Raw materials

Raw materials

Preparation Products

TEAD-IN-10 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

3032196-65-6 (TEAD-IN-10) Related Search:

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TEAD-IN-10 2-Propen-1-one, 1-[3-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1-azetidinyl]- 3032196-65-6