2,3-Dichlorobenzoyl cyanide
- CAS No.
- 77668-42-9
- Chemical Name:
- 2,3-Dichlorobenzoyl cyanide
- Synonyms
- 2,3-Dichlorobenzoylc;Lamotrigine Impurity 5;Lamotrigine Impurity 10;Lamotrigine Impurity 25;2,3-DichloroBenzoylNitrile;2,3-dichlorobenozyl cyanide;2,3-DICHLOROBENZOYL CYANIDE;Dichlorobenzoyl Lamotrigine;Lamotrigine 2,3-DCBN Impurity;2,3-Dichlorobenzoyl cyanide, 98%
- CBNumber:
- CB8147167
- Molecular Formula:
- C8H3Cl2NO
- Molecular Weight:
- 200.02
- MDL Number:
- MFCD00792559
- MOL File:
- 77668-42-9.mol
- MSDS File:
- SDS
| Melting point | 52-53 °C(Solv: ligroine (8032-32-4)) |
|---|---|
| Boiling point | 309°C |
| Density | 1.446 |
| Flash point | 141°C |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| color | Cream |
| InChI | InChI=1S/C8H3Cl2NO/c9-6-3-1-2-5(8(6)10)7(12)4-11/h1-3H |
| InChIKey | FIBBFBXFASKAON-UHFFFAOYSA-N |
| SMILES | C1(C(=O)C#N)=CC=CC(Cl)=C1Cl |
| CAS DataBase Reference | 77668-42-9(CAS DataBase Reference) |
| FDA UNII | 3K95NM9ZHZ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H311+H331-H315-H319-H400 |
| Precautionary statements | P501-P261-P273-P270-P271-P264-P280-P391-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P405 |
| Hazard Codes | Xi |
| RIDADR | UN3439 |
| Hazard Note | Irritant |
| HazardClass | 6.1 |
| HS Code | 2926907090 |
| REACH Registrations | Active |
| Limited Quantities | 0.5 Kg (solid) |
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) |
2,3-Dichlorobenzoyl cyanide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-D432250-1G | 2,3-Dichlorobenzoyl Nitrile | 77668-42-9 | 1g | $191 | 2026-06-03 | Buy |
| TRC | TRC-D432250-10G | 2,3-Dichlorobenzoyl Nitrile | 77668-42-9 | 10g | $579 | 2026-06-03 | Buy |
| Apolloscientific | OR0344 | (2,3-Dichlorophenyl)(oxo)acetonitrile >98% | 77668-42-9 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR0344 | (2,3-Dichlorophenyl)(oxo)acetonitrile >98% | 77668-42-9 | 25g | $48 | 2026-06-04 | Buy |
| Apolloscientific | OR0344 | (2,3-Dichlorophenyl)(oxo)acetonitrile >98% | 77668-42-9 | 100g | $170 | 2026-06-04 | Buy |
2,3-Dichlorobenzoyl cyanide Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
2,3-Dichlorobenzoyl cyanide is an impurity of Lamotrigine (L173250), an anticonvulsant that is used in the treatment of bipolar and depression.
Synthesis
2905-60-4
143-33-9
77668-42-9
1. Synthesis of 2,3-dichlorobenzoyl cyanide 2,3-Dichlorobenzoyl chloride (20.0 g, 100 mmol) and cuprous iodide (I) (0.90 g, 4.7 mmol) were suspended in acetonitrile (50 mL) and stirred at room temperature until a yellow homogeneous solution was formed. Solid sodium cyanide (5.15 g, 110 mmol) was added slowly with a controlled addition time of 5-8 hours. After addition, stirring of the reaction mixture was continued for 1 h. The reaction progress was monitored by HPLC. The resulting inorganic salt (mainly NaCl) was removed by filtration and the filter cake was washed with acetonitrile (15 mL). Acetonitrile was removed by distillation under reduced pressure (~150 mbar). Sodium metabisulfite (Na2S2O3, 0-4 g, 3 mmol) was added to remove trace iodine. Finally, the product was purified by vacuum distillation (jacket temperature 140°C, boiling point 115°C/2 mbar) to give 2,3-dichlorobenzoyl cyanide in >80% yield and 100% purity (as determined by analytical HPLC) with a melting point of 60°C.
References
[1] Patent: WO2008/19798, 2008, A1. Location in patent: Page/Page column 12
2,3-Dichlorobenzoyl cyanide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Huaian Jiamu Biotechnology Co., Ltd. | 0517-83187139 18205232085 | cai@jiamu-bio.com | China | 2999 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Danyang Wanlong Chemical Co., Ltd | 86-511-8681 0993 | jeff@wanlongchem.com | China | 63 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
View Lastest Price from 2,3-Dichlorobenzoyl cyanide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-13 | 2,3-Dichlorobenzoyl cyanide
77668-42-9
|
$10.00 | 1ASSAYS | 99% | 1 ton | RongNa Biotechnology Co.,Ltd | |
 |
2026-09-11 | 2,3-Dichlorobenzoyl cyanide
77668-42-9
|
$750.00-980.00 | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-08-25 | 2,3-Dichlorobenzoyl cyanide
77668-42-9
|
$2.00-6.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- 2,3-Dichlorobenzoyl cyanide
77668-42-9
- $10.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- 2,3-Dichlorobenzoyl cyanide
77668-42-9
- $750.00-980.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 2,3-Dichlorobenzoyl cyanide
77668-42-9
- $2.00-6.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
77668-42-9(2,3-Dichlorobenzoyl cyanide )Related Search:
1of4
