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N-omega-Hydroxy-nor-L-arginine, diacetate salt

CAS No.
189302-40-7
Chemical Name:
N-omega-Hydroxy-nor-L-arginine, diacetate salt
Synonyms
N-omega-Hydroxy-L-norarginine;nor-NOHA diacetate;NOR-NOHA, 2CH3CO2H;N-w-Hydroxy-L-norarginine;N-o-Hydroxy-L-norarginine;N---Hydroxy-nor-L-arginine;N-w-Hydroxy-L-norarginine diacetate salt;N-ω-Hydroxy-L-norarginine diacetate salt;N-omega-Hydroxy-nor-L-arginine, diacetate salt;(S,E)-2-aMino-4-(2-hydroxyguanidino)butanoic acid
CBNumber:
CB8149237
Molecular Formula:
C5H12N4O3
Molecular Weight:
176.17
MDL Number:
MFCD01318777
MOL File:
189302-40-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:17

N-omega-Hydroxy-nor-L-arginine, diacetate salt Properties

Boiling point 391.515±52.00 °C(Press: 760.00 Torr)(predicted)
Density 1.634±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Store at 0°C
solubility water: 50 mg/mL
form White to slightly yellowish powder.
pka 2.209±0.10(predicted)
color off-white
Water Solubility water: 50mg/mL
InChIKey PQFYTZJPYBMTCT-QTNFYWBSSA-N
SMILES N(O)\C(=N\CC[C@H](N)C(=O)O)\N.OC(=O)C.OC(=O)C
FDA UNII U0F1149OFR
UNSPSC Code 12352209
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  WGK 1
Storage Class 11 - Combustible Solids

N-omega-Hydroxy-nor-L-arginine, diacetate salt price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 399275 Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem 189302-40-7 1mg $61.9 2026-04-30 Buy
Sigma-Aldrich 399275 Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem 189302-40-7 5mg $159 2026-04-30 Buy
Usbiological 279918 N-w-Hydroxy-L-norarginine Asreported 189302-40-7 10mg $349 2026-06-03 Buy
Usbiological 279918 N-w-Hydroxy-L-norarginine Asreported 189302-40-7 25mg $462 2026-06-03 Buy
Usbiological 279918 N-w-Hydroxy-L-norarginine Asreported 189302-40-7 50mg $675 2026-06-03 Buy
Product number Packaging Price Buy
399275 1mg $61.9 Buy
399275 5mg $159 Buy
279918 10mg $349 Buy
279918 25mg $462 Buy
279918 50mg $675 Buy

N-omega-Hydroxy-nor-L-arginine, diacetate salt Chemical Properties, Uses, Production

Chemical Properties

Off-white powder

Uses

A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 µM) and mouse macrophages (IC50 = 50 µM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS.

Definition

ChEBI: Nomega-hydroxy-nor-l-arginine is a L-alpha-amino acid.

General Description

A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 μM) and mouse macrophages (IC50 = 50 μM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS.

Biochem/physiol Actions

Primary Targetarginase from rat liver

N-omega-Hydroxy-nor-L-arginine, diacetate salt Preparation Products And Raw materials

Raw materials

Preparation Products

N-omega-Hydroxy-nor-L-arginine, diacetate salt Suppliers

Global Suppliers ( 18)
Supplier Tel Email Country ProdList Advantage
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Shenzhen Chim Biotech Co., Ltd. 13692196024 sales@chimchem.com China 500 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Nextpeptide Inc +86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19904 58
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19684 58
TCI (Shanghai) Chemical Trading Co., Ltd. 021-61109150 sales@tcisct.com China 29717 58
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25030 58
L-2-AMINO-(4-(2'-HYDROXYGUANIDINO)BUTYRIC ACID), 2CH3CO2H N---Hydroxy-nor-L-arginine (S,E)-2-aMino-4-(2-hydroxyguanidino)butanoic acid L-2-AMino-4-(2'-hydroxyguanidino)-butyric acid, nor-NOHA, H-Nar(OH)-OH N-o-Hydroxy-L-norarginine L-2-Amino-{4-(2'-hydroxyguanidino)butyric acid diacetate nor-NOHA diacetate N-w-Hydroxy-L-norarginine diacetate salt≥ 97% (TLC) NOR-NOHA, 2CH3CO2H N-w-Hydroxy-L-norarginine Butanoic acid, 2-amino-4-[[(hydroxyamino)iminomethyl]amino]-, (2S)- N-w-Hydroxy-L-norarginine diacetate salt Nω-Hydroxy-nor-L-arginine, Diacetate Salt N-ω-Hydroxy-L-norarginine diacetate salt N-omega-Hydroxy-L-norarginine N-omega-Hydroxy-nor-L-arginine, diacetate salt 189302-40-7 proteins