2-Chloromethyloxazole
- CAS No.
- 185246-17-7
- Chemical Name:
- 2-Chloromethyloxazole
- Synonyms
- 2-CHLOROMETHYL-OXAZOLE;Lactic Acid Impurity 17;OXAZOLE, 2-(CHLOROMETHYL)-;2-(Chloromethyl)-1,3-oxazole
- CBNumber:
- CB8171649
- Molecular Formula:
- C4H4ClNO
- Molecular Weight:
- 117.53
- MDL Number:
- MFCD04114926
- MOL File:
- 185246-17-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H335-H314 |
| Precautionary statements | P260-P264-P270-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P403+P233-P405-P501 |
| HS Code | 2934999090 |
2-Chloromethyloxazole price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 230225 | 2-Chloromethyl-oxazole 98+% ≥98%(Assay) | 185246-17-7 | 100mg | $347 | 2026-06-03 | Buy |
| Usbiological | 230225 | 2-Chloromethyl-oxazole 98+% ≥98%(Assay) | 185246-17-7 | 250mg | $501 | 2026-06-03 | Buy |
| Usbiological | 230225 | 2-Chloromethyl-oxazole 98+% ≥98%(Assay) | 185246-17-7 | 1g | $895 | 2026-06-03 | Buy |
| AstaTech | 24216 | 2-CHLOROMETHYL-OXAZOLE 95% | 185246-17-7 | 0.25G | $95 | 2026-04-30 | Buy |
| AstaTech | 24216 | 2-CHLOROMETHYL-OXAZOLE 95% | 185246-17-7 | 1G | $250 | 2026-04-30 | Buy |
2-Chloromethyloxazole Chemical Properties, Uses, Production
Synthesis
130551-92-7
185246-17-7
General procedure for the synthesis of 2-(chloromethyl)oxazole from 2-hydroxymethyl oxazole: Thionyl chloride (SOCl2, 3.25 mL, 45 mmol) was added slowly and dropwise to a solution of 2-hydroxymethyl oxazole (450 mg, 4.5 mmol) in dichloromethane (DCM, 25 mL) at 0 °C. The reaction mixture was stirred at 0 °C for 1 hour. Subsequently, water (50 mL) and ethyl acetate (EtOAc, 60 mL) were added to the reaction system for extraction. The organic and aqueous phases were separated, and the organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford 2-(chloromethyl)oxazole as a white solid (200 mg, 1.7 mmol, 37% yield).
References
[1] Patent: WO2017/93543, 2017, A2. Location in patent: Page/Page column 101
[2] Patent: WO2007/34144, 2007, A1. Location in patent: Page/Page column 93
[3] Patent: WO2011/35009, 2011, A1. Location in patent: Page/Page column 46
2-Chloromethyloxazole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Shanghai Feibo Chemical Technology Co., Ltd | 021-58955608,2250286 15921236618 | blinkzeng@gmail.com | China | 522 | 62 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 |
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