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2-Methoxy-2-methyl-propylamine

2-Methoxy-2-methyl-propylamine Structure
2-Methoxy-2-methyl-propylamine structure
CAS No.
89282-70-2
Chemical Name:
2-Methoxy-2-methyl-propylamine
Synonyms
2-methoxy-2-methylpropan-1-amine;CHEMBRDG-BB 4100459;2-METHOXYISOBUTYLAMINE;2-Methoxy-2-methyl-propylamine;2-Methoxy-2-methyl-1-propanamine;1-Amino-2-methoxy-2-methylpropane;2-Methoxy-2-methyl-propyl-1-amine;1-Propanamine, 2-methoxy-2-methyl-;2-Methoxy-2-methyl-1-propanamine HCl;2-Methoxy-2-methyl-propylamine, 98 %
CBNumber:
CB8172136
Molecular Formula:
C5H13NO
Molecular Weight:
103.16
MDL Number:
MFCD01821229
MOL File:
89282-70-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:24
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2-Methoxy-2-methyl-propylamine Properties

Boiling point 115-125 °C
Density 0.8677 g/cm3
refractive index 1.41
pka 8.88±0.10(Predicted)
InChI InChI=1S/C5H13NO/c1-5(2,4-6)7-3/h4,6H2,1-3H3
InChIKey ZSTYQALWKOGXOV-UHFFFAOYSA-N
SMILES C(N)C(OC)(C)C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302+H312+H332-H314
Precautionary statements  P280-P305+P351+P338-P310
Hazard Codes  Xi
Risk Statements  43
Safety Statements  36/37
RIDADR  2735
HazardClass  IRRITANT
PackingGroup  Ⅲ
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

2-Methoxy-2-methyl-propylamine price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 040360 (2-Methoxy-2-methylpropyl)amine oxalate 89282-70-2 500.00mg $315 2026-05-18 Buy
Synthonix M6043 2-Methoxy-2-methylpropylamine 97% 89282-70-2 1g $190 2026-05-06 Buy
Synthonix M6043 2-Methoxy-2-methylpropylamine 97% 89282-70-2 5g $870 2026-05-06 Buy
aablocks AA0087DE 2-Methoxy-2-Methylpropan-1-Amine 98% 89282-70-2 250mg $57 2026-05-28 Buy
aablocks AA0087DE 2-Methoxy-2-Methylpropan-1-Amine 98% 89282-70-2 1g $90 2026-05-28 Buy
Product number Packaging Price Buy
040360 500.00mg $315 Buy
M6043 1g $190 Buy
M6043 5g $870 Buy
AA0087DE 250mg $57 Buy
AA0087DE 1g $90 Buy

2-Methoxy-2-methyl-propylamine Chemical Properties, Uses, Production

Uses

2-Methoxy-2-methylpropan-1-amine is a useful research chemical used in the preparation of diaryl dihydropyrazolo[3,4-c]pyridinones and dihydropyrazolo[3,4-f][1,4]oxazepinones as bicyclic lactam-based cannabinoid-1 receptor antagonists for the treatment of obesity.

Synthesis

2-METHOXY-2-METHYLPROPYL BROMIDE

19752-21-7

Potassium phthalimide

1074-82-4

2-METHOXY-2-METHYL-PROPYLAMINE

89282-70-2

Example 3 Synthesis of 2-methoxy-2-methylpropylamine: phthalimide potassium salt (3.70 g, 20 mmol) was added to a solution of 1-bromo-2-methoxy-2-methylpropane (3.34 g, 20 mmol) dissolved in 100 mL of dimethylformamide. The reaction mixture was refluxed with stirring for 4 hours, followed by slow cooling to 25°C. After adding 200 mL of chloroform, the mixture was poured into 500 mL of cold water. The aqueous phase was separated and extracted with two 50 mL chloroform. The combined chloroform extracts were washed sequentially with 100 mL of 0.2 N sodium hydroxide solution and 100 mL of water. After drying, the chloroform was removed under reduced pressure. The residue was dissolved in 100 mL of methanol, hydrazine hydrate (2 g, 40 mmol) was added and heated at reflux for 1 hour. After completion of the reaction, methanol was removed by concentration under reduced pressure. Concentrated hydrochloric acid was added to the residual aqueous solution and heated at reflux for 1 hour. Subsequently, it was concentrated under reduced pressure to remove most of the hydrochloric acid. The pH of the wet residue was adjusted to 14 with sodium hydroxide solution and poured into a separatory funnel containing a saturated potassium carbonate solution. The resulting solution was distilled at atmospheric pressure and the product 2-methoxy-2-methylpropylamine (1.6 g, 78% yield) was collected at 125 °C. The product was characterized by infrared spectroscopy (neat) and the major absorption peaks were located at 3280, 3065, 2960, 2920, 1640, 1430, 1365, 1075 cm1.

References

[1] Patent: US5210270, 1993, A

2-Methoxy-2-methyl-propylamine Preparation Products And Raw materials

Raw materials

1H-Isoindol-1-one, 3-hydroxy- 2-Methoxy-2-methylpropyl bromide Potassium phthalimide 2-Methoxy-2-methyl-1-propanol Methanol
Sodium hydroxide N-Methylacetamide Hydrochloric acid Chloroform Water

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Preparation Products

2-Methoxyisobutyl isocyanide N-Formyl-2-methoxy-2-methyl-propylamine

2-Methoxy-2-methyl-propylamine Suppliers

Global Suppliers ( 60)
Supplier Tel Email Country ProdList Advantage
Shanghai Naiys Biological Technology Co., Ltd 18321139117 316441092@qq.con China 3185 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
ChemFuture PharmaTech (Jiangsu) Ltd 5108538618 suger.wang@chemfuture.com China 832 65
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9331 58
AN PharmaTech Co Ltd 86(21)68097365 sales@anpharma.net China 4875 55
Struchem Co., Ltd. 0512-63009836 18994340901 helen@struchem.com China 3970 60
Supplier Advantage
Shanghai Naiys Biological Technology Co., Ltd 58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
ChemFuture PharmaTech (Jiangsu) Ltd 65
Beijing Ouhe Technology Co., Ltd 60
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Raise Chemical Technology Co.,Ltd 55
Amatek Scientific Co. Ltd. 55
Finetech Industry Limited 58
AN PharmaTech Co Ltd 55
Struchem Co., Ltd. 60

View Latest Price from 2-Methoxy-2-methyl-propylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-METHOXY-2-METHYL-PROPYLAMINE pictures 2019-08-07 2-METHOXY-2-METHYL-PROPYLAMINE
89282-70-2
 $1.00 1KG 98% 1kg，5kg，100kg Career Henan Chemical Co

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1of4

2-METHOXYISOBUTYLAMINE CHEMBRDG-BB 4100459 (2-methoxy-2-methylpropyl)amine(SALTDATA: FREE) 2-Methoxy-2-Methylpropan-1-aMine hydrochloride 2-Methoxy-2-methyl-propylamine, 98 % 2-Methoxy-2-methyl-1-propanamine HCl 2-Methoxy-2-methyl-propyl-1-amine 1-Propanamine, 2-methoxy-2-methyl- 2-Methoxy-2-methyl-1-propanamine 1-Amino-2-methoxy-2-methylpropane 2-Methoxy-2-methylpropylamine - [M6043] 2-methoxy-2-methylpropan-1-amine 2-Methoxy-2-methyl-propylamine 89282-70-2