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Z-YVAD-AFC

Z-YVAD-AFC structure

CAS No.: 201608-13-1

Chemical Name:: Z-YVAD-AFC

Synonyms: Z-YVAD-AFC;Z-TYR-VAL-ALA-ASP-AFC;Z-TRY-VAL-ALA-ASP-AFC;caspase-1 substrate VI;PASE-1 Substrate (AFC);CASPASE-1 SUBSTRATE (AFC);CASPASE-1, SUBSTRATE, FLUOROGENIC;CASPASE-1 SUBSTRATE VI, FLUOROGENIC;Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin;Z (CARBOBENZOXY)-TYR-VAL-ALA-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC

CBNumber:: CB8208343

Molecular Formula:: C39H40F3N5O11

Molecular Weight:: 811.76

MDL Number:: MFCD00797534

MOL File:: 201608-13-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:44

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Z-YVAD-AFC Properties

Boiling point	1102.5±65.0 °C(Predicted)
Density	1.411±0.06 g/cm3(Predicted)
storage temp.	-20°C
form	White to off-white powder.
pka	4.09±0.10(Predicted)
Appearance	White to Off-white Powder
Sequence	Z-Tyr-Val-Ala-{Asp-AFC}

Z-YVAD-AFC price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0654095	Z-YVAD-AFC 98.85%	201608-13-1	1mg	$103	2026-06-04	Buy
ChemScene	CS-0654095	Z-YVAD-AFC 98.85%	201608-13-1	5mg	$206	2026-06-04	Buy
ChemScene	CS-0654095	Z-YVAD-AFC 98.85%	201608-13-1	10mg	$357	2026-06-04	Buy
ChemScene	CS-0654095	Z-YVAD-AFC 98.85%	201608-13-1	25mg	$758	2026-06-04	Buy
Chem-Impex	07609	Z-Tyr-Val-Ala-Asp-AFC	201608-13-1	5MG	$154.7	2026-05-19	Buy

Product number	Packaging	Price	Buy
CS-0654095	1mg	$103	Buy
CS-0654095	5mg	$206	Buy
CS-0654095	10mg	$357	Buy
CS-0654095	25mg	$758	Buy
07609	5MG	$154.7	Buy

Z-YVAD-AFC Chemical Properties, Uses, Production

Description

The presence of halogen substituents on the fluorescent group improves the membrane permeability of YVAD-derived Caspase-1 substrate Z-YVAD-AFC.

Uses

Z-YVAD-AFC is a fluorescent substrate for Caspase-1, which can be used to detect and measure the activity of Caspase-1[1].

References

[1] Vikas Kaushal, et al. P2-120: Inflammasome-mediated activation of caspase-1 and caspase-6 in primary human neurons. Volume8,Issue4S_Part_8.Alzheimer 's Association International Conference 2012.

Sequene

Cbz-Tyr-Val-Ala-Asp-AFC

Z-YVAD-AFC Preparation Products And Raw materials

Raw materials

Preparation Products

Z-YVAD-AFC Suppliers

Global Suppliers ( 51)

Supplier	Tel	Email	Country	ProdList	Advantage
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Nanjing Leon Biological Technology Co., Ltd.	025-84523390 -127; 17705183659	sales@njleonbiotech.com	China	5501	55
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19087	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10378	58
Nanjing chengqimei Biotechnology Co., Ltd	19850819832	2173594524@qq.com	China	2638	58
Nanchang Tianzhen Biotechnology Co., Ltd	13758194781 13173652190	522013271@qq.com	China	2436	58

Supplier	Advantage
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Nanjing Leon Biological Technology Co., Ltd.	55
Nanjing Peptide Biotech Ltd.	55
Hangzhou Peptidego Biotech Co.,Ltd.	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
Nanjing chengqimei Biotechnology Co., Ltd	58
Nanchang Tianzhen Biotechnology Co., Ltd	58

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Z (CARBOBENZOXY)-TYR-VAL-ALA-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC Z-TRY-VAL-ALA-ASP-AFC Z-TYR-VAL-ALA-ASP-AFC Z-YVAD-AFC CASPASE-1 SUBSTRATE (AFC) CASPASE-1, SUBSTRATE, FLUOROGENIC CASPASE-1 SUBSTRATE VI, FLUOROGENIC caspase-1 substrate VI Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- N-[(Phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine PASE-1 Substrate (AFC) 201608-13-1 C39H40F3N5O11