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| | Z-YVAD-AFC Basic information |
| Product Name: | Z-YVAD-AFC | | Synonyms: | Z (CARBOBENZOXY)-TYR-VAL-ALA-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;Z-TRY-VAL-ALA-ASP-AFC;Z-TYR-VAL-ALA-ASP-AFC;Z-YVAD-AFC;CASPASE-1 SUBSTRATE (AFC);CASPASE-1, SUBSTRATE, FLUOROGENIC;CASPASE-1 SUBSTRATE VI, FLUOROGENIC;caspase-1 substrate VI | | CAS: | 201608-13-1 | | MF: | C39H40F3N5O11 | | MW: | 811.76 | | EINECS: | | | Product Categories: | | | Mol File: | 201608-13-1.mol |  |
| | Z-YVAD-AFC Chemical Properties |
| Boiling point | 1102.5±65.0 °C(Predicted) | | density | 1.411±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | form | White to off-white powder. | | pka | 4.09±0.10(Predicted) | | Appearance | White to Off-white Powder | | Sequence | Z-Tyr-Val-Ala-{Asp-AFC} |
| | Z-YVAD-AFC Usage And Synthesis |
| Description | The presence of halogen substituents on the fluorescent group improves the membrane permeability of YVAD-derived Caspase-1 substrate Z-YVAD-AFC. | | Uses | Z-YVAD-AFC is a fluorescent substrate for Caspase-1, which can be used to detect and measure the activity of Caspase-1[1]. | | References | [1] Vikas Kaushal, et al. P2-120: Inflammasome-mediated activation of caspase-1 and caspase-6 in primary human neurons. Volume8,Issue4S_Part_8.Alzheimer 's Association International Conference 2012. | | Sequene | Cbz-Tyr-Val-Ala-Asp-AFC |
| | Z-YVAD-AFC Preparation Products And Raw materials |
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