α-Ketoglutaric acid-d6, α-Ketopentanoic acid-d6
- CAS No.
- 1173021-86-7
- Chemical Name:
- α-Ketoglutaric acid-d6, α-Ketopentanoic acid-d6
- Synonyms
- EOS-60378;α-Ketoglutaric acid-d6;2-Ketoglutaric acid-d6;α-Ketopentanoic acid-d6;2-Ketopentanedioic acid-d6;α-Ketoglutaric acid (D?, 98%);2-Oxo-1,5-pentanedioic Acid-d6;2-Ketoglutaric acid-d6;ALPHA-KETOGLUTARIC ACID (D6, 98%);2-oxopentanedioic-3,3,4,4-d4acid-d2
- CBNumber:
- CB82092289
- Molecular Formula:
- C5D6O5
- Molecular Weight:
- 152.135110668
- MDL Number:
- MFCD00190469
- MOL File:
- 1173021-86-7.mol
- MSDS File:
- SDS
| Melting point | 114-117 °C |
|---|---|
| form | Solid |
| color | White to off-white |
| InChI | 1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)/i1D2,2D2/hD2 |
| InChIKey | KPGXRSRHYNQIFN-DTDGFSOZSA-N |
| SMILES | [2H]OC(=O)C(=O)C([2H])([2H])C([2H])([2H])C(=O)O[2H] |
| UNSPSC Code | 12352115 |
| CAS Number Unlabeled | 328-50-7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H318-H335 |
| Precautionary statements | P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-39 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
α-Ketoglutaric acid-d6, α-Ketopentanoic acid-d6 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0564127 | 2-Ketoglutaric acid-d6 ≥98% | 1173021-86-7 | 10mg | $578 | 2026-06-04 | Buy |
| American Custom Chemicals Corporation | RDL0001552 | 2-KETOPENTANEDIOIC ACID-D6 95.00% | 1173021-86-7 | 5MG | $900.94 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0001552 | 2-KETOPENTANEDIOIC ACID-D6 95.00% | 1173021-86-7 | 100MG | $2312.5 | 2021-12-16 | Buy |
α-Ketoglutaric acid-d6, α-Ketopentanoic acid-d6 Chemical Properties, Uses, Production
Uses
2-Ketoglutaric acid-d6 is the deuterium labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35. DOI:10.1128/MMBR.00038-15
[3] Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec105(Pt 3):1654-1662. DOI:10.1016/j.ijbiomac.2016.12.015
α-Ketoglutaric acid-d6, α-Ketopentanoic acid-d6 Preparation Products And Raw materials
Raw materials
Preparation Products
α-Ketoglutaric acid-d6, α-Ketopentanoic acid-d6 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
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| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4721 | 58 |
