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4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile Structure
4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile structure
CAS No.
89487-99-0
Chemical Name:
4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile
Synonyms
5-Cyano-3,4-dih;4-Hydroxy-2-(methylthio);5-Cyano-2-(Methylthio)pyriMidine-4-one;5-Cyano-4-hydroxy-2-(methylthio)pyrimidine;5-Cyano-3,4-dihydro-2-methylthiopyrimidin-4-one;4-hydroxy-2-(methylthio)pyrimidine-5-carbonitrile;_x000D_5-Cyano-4-hydroxy-2-(methylthio)pyrimidine;2-methylsulfanyl-6-oxo-1H-pyrimidine-5-carbonitrile;4-Hydroxy-2-Methylsulfanyl-pyriMidine-5-carbonitrile;4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile ,97%
CBNumber:
CB82129408
Molecular Formula:
C6H5N3OS
Molecular Weight:
167.19
MDL Number:
MFCD00831720
MOL File:
89487-99-0.mol
MSDS File:
SDS
Last updated:2026-05-28 03:43:56
Request For Quotation

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile Properties

Melting point 222-224℃ (isopropanol )
Density 1.42±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Sealed in dry,Room Temperature
pka 5.38±0.50(Predicted)
Appearance Light yellow to yellow Solid
InChI InChI=1S/C6H5N3OS/c1-11-6-8-3-4(2-7)5(10)9-6/h3H,1H3,(H,8,9,10)
InChIKey XTLKENCFQIAAJK-UHFFFAOYSA-N
SMILES C1(SC)NC(=O)C(C#N)=CN=1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P280-P305+P351+P338-P310
Risk Statements  20/21/22-36/37/38
Safety Statements  22-26-36/37/39
RIDADR  3439
HS Code  29335990

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FH155456 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 89487-99-0 0.5g $900 2026-06-04 Buy
Biosynth FH155456 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 89487-99-0 5g $900 2026-06-04 Buy
Biosynth FH155456 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 89487-99-0 2g $900 2026-06-04 Buy
Biosynth FH155456 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 89487-99-0 1g $900 2026-06-04 Buy
Biosynth FH155456 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 89487-99-0 10g $900 2026-06-04 Buy
Product number Packaging Price Buy
FH155456 0.5g $900 Buy
FH155456 5g $900 Buy
FH155456 2g $900 Buy
FH155456 1g $900 Buy
FH155456 10g $900 Buy

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile Chemical Properties, Uses, Production

Chemical Properties

White solid

Synthesis

Methyl carbamimidothioate

2986-19-8

Ethyl (ethoxymethylene)cyanoacetate

94-05-3

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile

89487-99-0

2-Methyl-2-isothiourea (5 mmol) and ethyl ethoxycarbonylcyanoacetate (5 mmol) were dissolved in 20 mL of ethanol. Potassium carbonate (10 mmol) was added to the solution. The reaction mixture was refluxed for 48 hours, followed by cooling to room temperature and filtration. The filtrate was concentrated under reduced pressure and purified by column chromatography to afford 4-hydroxy-2-(methylthio)pyrimidine-5-carbonitrile in 65% yield.

References

[1] Patent: US2008/255172, 2008, A1. Location in patent: Page/Page column 70

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile synthesis

42466-67-1
867-44-7
89487-99-0
Synthesis of 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile from (E)-Ethyl 2-cyano-3-ethoxyacrylate and 2-Methyl-2-thiopseudourea sulfate

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile Preparation Products And Raw materials

Raw materials

Acetic anhydride Potassium hydroxide Triethyl orthoformate Diethyl ether 2-Methyl-2-thiopseudourea sulfate
Methanol Ethyl cyanoacetate Methyl carbamimidothioate Ethyl (ethoxymethylene)cyanoacetate Potassium carbonate

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Preparation Products

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile Suppliers

Global Suppliers ( 87)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 sales@sun-shinechem.com China 1197 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Worldyang Chemical Co.,Ltd. 021-56795766 sales@worldyachem.com China 9475 58
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Shanghai Jovan Biochemical Technology Co. Ltd. +86-021-61654350 1245958370@qq.com China 2979 50
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Pure Chemistry Scientific Inc. 62
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai Topbiochem Technology Co., Ltd 58
Shanghai Raise Chemical Technology Co.,Ltd 55
Bide Pharmatech Ltd. 60
Shanghai Worldyang Chemical Co.,Ltd. 58
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55
Shanghai Jovan Biochemical Technology Co. Ltd. 50

View Latest Price from 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile ,97% pictures 2026-08-20 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile ,97%
89487-99-0
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile pictures 2022-01-04 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile
89487-99-0
 1g 98%min 100kgs/month Shanghai Rlavie Technology Co ltd
4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile pictures 2020-01-10 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile
89487-99-0
 $6.68 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile Spectrum

4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile(89487-99-0)1HNMR

89487-99-0 (4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile) Related Search:

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4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile ,97% 5-Cyano-4-hydroxy-2-(methylthio)pyrimidine 4-hydroxy-2-(methylthio)pyrimidine-5-carbonitrile 5-Cyano-2-(Methylthio)pyriMidine-4-one 4-Hydroxy-2-Methylsulfanyl-pyriMidine-5-carbonitrile 5-Cyano-3,4-dihydro-2-methylthiopyrimidin-4-one 2-(Methylthio)-6-oxo-1,6-dihydropyriMidine-5-carbonitrile 2-(methylthio)-4-oxo-1,4-dihydropyrimidine-5-carbonitrile 4-Hydroxy-2-(methylthio) 5-Cyano-3,4-dih 5-Pyrimidinecarbonitrile, 1,6-dihydro-2-(methylthio)-6-oxo- _x000D_5-Cyano-4-hydroxy-2-(methylthio)pyrimidine 2-Methylsulfanyl-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile 4-Hydroxy-2-(methylthio)pyrimidine-5-carbonitrile ,97% ISO 9001：2015 REACH 2-methylsulfanyl-6-oxo-1H-pyrimidine-5-carbonitrile 2-(methylsulfanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitril... 89487-99-0 Heterocycle-Pyrimidine series pyrimidine