ChemicalBook >> CAS DataBase List >>2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate structure

CAS No.: 92052-29-4

Chemical Name:: 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate

Synonyms: [(2S,3R,4S,5S,6S)-3,4,5-triacetoxy-6-(2,2,2-trichloroethanimidoyl)oxy-tetrahydropyran-2-yl]methyl acetate;2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl 2,2,2-Trichloroacetimidate;2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl trichloroacetimidate;2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate;2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl trichloroacetimidate;2,3,4,6-tetra-O-acetyl-β-D-galacto-pyranosyl trichloroacetimidate;2,3,4,6-Tetra-O-acetyl-1-O-trichloroacetimidoyl-β-D-glucopyranoside;2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl 2,2,2-Trichloroacetimidate;2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate, 98%(N)

CBNumber:: CB82129741

Molecular Formula:: C16H20Cl3NO10

Molecular Weight:: 492.69

MDL Number:: MFCD11112189

MOL File:: 92052-29-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-21 11:58:00

Request For Quotation

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate Properties

Melting point	154.0 to 160.0 °C
Boiling point	463.3±55.0 °C(Predicted)
Density	1.55±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
form	powder to crystal
pka	1.39±0.70(Predicted)
color	White to Almost white
InChI	InChI=1/C16H20Cl3NO10/c1-6(21)25-5-10-11(26-7(2)22)12(27-8(3)23)13(28-9(4)24)14(29-10)30-15(20)16(17,18)19/h10-14,20H,5H2,1-4H3/t10-,11-,12+,13-,14+/s3
InChIKey	IBUZGVQIKARDAF-SZYILJKCNA-N
SMILES	C(Cl)(C(=N)O[C@@H]1O[C@@H]([C@H]([C@H](OC(C)=O)[C@H]1OC(=O)C)OC(C)=O)COC(C)=O)(Cl)Cl \|&1:5,7,8,9,14,r\|

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P280-P261-P271
HS Code	2940000080

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	T2491	2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl 2,2,2-Trichloroacetimidate >98.0%(N)	92052-29-4	1g	$112	2026-04-30	Buy
TCI Chemical	T2491	2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl 2,2,2-Trichloroacetimidate >98.0%(N)	92052-29-4	5g	$337	2026-04-30	Buy
Biosynth	MT10320	2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate	92052-29-4	1g	$317.46	2026-06-04	Buy
Biosynth	MT10320	2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate	92052-29-4	2g	$526.1	2026-06-04	Buy
Biosynth	MT10320	2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate	92052-29-4	5g	$1043.05	2026-06-04	Buy

Product number	Packaging	Price	Buy
T2491	1g	$112	Buy
T2491	5g	$337	Buy
MT10320	1g	$317.46	Buy
MT10320	2g	$526.1	Buy
MT10320	5g	$1043.05	Buy

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate Chemical Properties,Uses,Production

Uses

2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate, 98%(N) (2,3,4,6-Tetra-O-acetyl-&beta) can be used in glycobiology research.

Synthesis

2,3,4,6-TETRA-O-ACETYL-BETA-D-GLUCOPYRANOSE

3947-62-4

545-06-2

2,3,4,6-TETRA-O-ACETYL-ALPHA-D-GLUCOPYRANOSYL TRICHLOROACETIMIDATE

74808-10-9

1. (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-hydroxytetrahydro-2H-pyran-3,4,5-triyl triacetate (5 g, 12.8 mmol) was dissolved in DMF (60 mL) and hydrazine acetate (1.3 g, 14.1 mmol) was added. The reaction mixture was stirred at room temperature overnight and subsequently concentrated to dryness under reduced pressure. The residue was dissolved with EtOAc (200 mL) and washed sequentially with saturated aqueous NaHCO3 and deionized water. The organic phase was dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. Purification by silica gel column chromatography (eluent: hexane-EtOAc, 1:1, v/v) afforded a white solid product (4.27 g, 96% yield). 2. The above product (2.1 g, 6.03 mmol), trichloroacetonitrile (12.1 mL, 121 mmol) and DCM (40 mL) were mixed and cooled to 0 °C. Cs2CO3 (1.96 g, 6.03 mmol) was added and stirred at room temperature for 1 hour. The reaction mixture was concentrated under reduced pressure and purified by silica gel column chromatography (eluent: hexane-EtOAc, 2:1, v/v) to give white solid sialyl ester (2.85 g, 96% yield). 3. The sialyl ester (0.88 g, 1.62 mmol), acceptor (0.73 g, 1.1 mmol), molecular sieve MS-4A and DCM (40 mL) were mixed and stirred at room temperature for 30 min. After cooling to -70 °C, TfOH (29 μL, 0.32 mmol) was added. The reaction mixture was stirred at -70 to -20 °C for 1 h and quenched with Et3N (0.05 mL). The mixture was diluted with DCM (200 mL), washed sequentially with saturated aqueous NaHCO3 and deionized water, the organic phase was dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. Purification by silica gel column chromatography (eluent: hexane-EtOAc, 3:2, v/v) gave a white solid disaccharide product (1.05 g, 95% yield). The 1H-NMR (500 MHz, CDCl3) and 13C-NMR (75 MHz, CDCl3) data were consistent with the structure of the target compound.

References

[1] Organic and Biomolecular Chemistry, 2017, vol. 15, # 26, p. 5602 - 5608
[2] Tetrahedron Letters, 2005, vol. 46, # 14, p. 2445 - 2448
[3] Patent: WO2012/135049, 2012, A1. Location in patent: Page/Page column 58-59
[4] Chemistry - An Asian Journal, 2014, vol. 9, # 7, p. 1786 - 1796
[5] Chinese Chemical Letters, 2016, vol. 27, # 12, p. 1740 - 1744

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate Preparation Products And Raw materials

Raw materials

2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranose Cesium carbonate Trichloroacetonitrile Dichloromethane

Preparation Products

1-Azido-2,3,4,6-tetra-O-acetyl-beta-D-glucose

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate Suppliers

Global( 93)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing Qinling Pharmaceutical Co., Ltd.	010-61241352 18901327973	834537306@qq.com	China	6234	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9874	58
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80
9ding chemical ( Shanghai) Limited	4009209199	sales@9dingchem.com	China	22497	55
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29985	65

Supplier	Advantage
Beijing Qinling Pharmaceutical Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Shanghai Longsheng chemical Co.,Ltd.	59
Shanghai T&W Pharmaceutical Co., Ltd.	58
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
9ding chemical ( Shanghai) Limited	55
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65

View Lastest Price from 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-09-11	2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate 92052-29-4		1G	98%min	30kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
	2019-12-23	2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate 92052-29-4	$1.00	1KG	97%-99.9%	100kg	Career Henan Chemical Co

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate
92052-29-4
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate
92052-29-4
$1.00
97%-99.9%
Career Henan Chemical Co

92052-29-4(2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate)Related Search:

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranose 1-Azido-2,3,4,6-tetra-O-acetyl-beta-D-glucose 2-Acetamido-2-deoxy-alpha-D-glucopyranosyl chloride 3,4,6-triacetate 4-Methylumbelliferyl-beta-D-glucopyranoside Diosgenin-3-O-Β-D-glucuronide

2,3,4-Tri-O-acetyl-α-D-glucuronic Acid Methyl Ester Phenyl 2,3,4,6-Tetra-O-acetyl-1-thio-a-D-mannopyranoside 2-Phenylethyl-beta-D-thiogalactoside Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-thioglucopyranoside α-D-Mannopyranosyl Fluoride

2-O-Benzyl-1,3,4,6-tetra-O-acetyl-a-D-mannopyranose Methyl 2,2,2-trichloroacetimidate 2,3,4-Tri-O-acetyl-beta-D-xylopyranosyl trichloroacetimidate 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate

1of3

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate 2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl trichloroacetimidate 2,3,4,6-Tetra-O-acetyl-1-O-trichloroacetimidoyl-beta-D-glucopyranoside min. 99% 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl trichloroacetimidate -D-glucopyranosyl 2,2,2-Trichloroacetimidate 2,3,4,6-Tetra-O-acetyl-&beta 2,3,4,6-Tetra-O-acetyl-1-O-trichloroacetimidoyl-β-D-glucopyranoside 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate [(2S,3R,4S,5S,6S)-3,4,5-triacetoxy-6-(2,2,2-trichloroethanimidoyl)oxy-tetrahydropyran-2-yl]methyl acetate 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl 2,2,2-Trichloroacetimidate [(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-(2,2,2-trichloroethanimidoyl)oxyoxan-2-yl]methyl acetate β-D-Glucopyranose, 2,3,4,6-tetraacetate 1-(2,2,2-trichloroethanimidate) (9CI, ACI) β-D-Glucopyranose, 2,3,4,6-tetraacetate 1-(2,2,2-trichloroethanimidate) 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl 2,2,2-Trichloroacetimidate, ≥ 98.0% (2R,3R,4S,5R,6S)-3,4,5-tris(acetyloxy)-6-[(2,2,2-trichloroethanimidoyl)oxy]oxan-2-yl]methyl acetate 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate, 98%(N) 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate，97% 2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl 2,2,2-trichloroacetimidate 2,3,4,6-Tetra-O-acetyl-1-O-trichloroacetimidoyl-beta-D-glucopyranoside 2,3,4,6-tetra-O-acetyl-β-D-galacto-pyranosyl trichloroacetimidate 92052-29-4