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2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA structure

CAS No.: 71432-55-8

Chemical Name:: 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

Synonyms: 2-TERT-BUTYL-1;3-DIISOPROPYLISOUREA;2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA;O-tert-Butyl-N,N'-diisopropylisourea;O-tert-Butyl-N,N'-diisopropylisourea;O-tert-Butyl-N,N'-diisopropylisourea >tert-Butyl N,N'-diisopropylcarbamimidate;tert-Butyl N,N'-diisopropylimidocarbamate;N,N'-diisopropyltert-butoxymethanimidamide;tert-butyl N,N'-bis(1-methylethyl)imidocarbamate

CBNumber:: CB8239657

Molecular Formula:: C11H24N2O

Molecular Weight:: 200.32

MDL Number:: MFCD06657672

MOL File:: 71432-55-8.mol

MSDS File:: SDS

Last updated:2025-08-08 17:45:00

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2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Properties

Boiling point	61°C/10mmHg(lit.)
Density	0.89±0.1 g/cm3(Predicted)
refractive index	1.4240-1.4280
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
form	clear liquid
pka	9.54±0.50(Predicted)
color	Colorless to Almost colorless
InChI	InChI=1S/C11H24N2O/c1-8(2)12-10(13-9(3)4)14-11(5,6)7/h8-9H,1-7H3,(H,12,13)
InChIKey	FESDUDPSRMWIDL-UHFFFAOYSA-N
SMILES	C(=NC(C)C)(OC(C)(C)C)NC(C)C

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
HS Code	2925290090

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B4178	O-tert-Butyl-N,N'-diisopropylisourea >98.0%(T)	71432-55-8	1g	$75	2025-07-31	Buy
TCI Chemical	B4178	O-tert-Butyl-N,N'-diisopropylisourea >98.0%(T)	71432-55-8	5g	$255	2025-07-31	Buy
TRC	B692565	2-tert-Butyl-1,3-diisopropylisourea	71432-55-8	2.5g	$160	2021-12-16	Buy
TRC	B692565	2-tert-Butyl-1,3-diisopropylisourea	71432-55-8	25g	$1260	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0098286	2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA 95.00%	71432-55-8	5G	$4966.5	2021-12-16	Buy

Product number	Packaging	Price	Buy
B4178	1g	$75	Buy
B4178	5g	$255	Buy
B692565	2.5g	$160	Buy
B692565	25g	$1260	Buy
CHM0098286	5G	$4966.5	Buy

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Chemical Properties,Uses,Production

Physical Form

liquid

Uses

2-tert-Butyl-1,3-diisopropylisourea is a useful synthetic intermediate in the synthesis of 5-Oxo Atorvastatin tert-Butyl Ester (O847160) which is a Boc-protected derivative of Atorvastatin. 2-tert-Butyl-1,3-diisopropylisourea is also used as a reagent in the total synthesis of Citrafungin A which is an antifungal natural product.

Synthesis

693-13-0

75-65-0

71432-55-8

GENERAL STEPS: CuCl (63.4 mg, 0.64 mmol, 1 mol%) was added to a solution of N,N'-diisopropylcarbodiimide (10.0 mL, 63.9 mmol, 1.0 equiv) in tert-butanol (6.97 mL, 73.5 mmol, 1.15 equiv). The reaction mixture was stirred at room temperature for 14 hours. After completion of the reaction, purification was carried out by distillation under reduced pressure (80°C, 25 mmHg). 2-tert-butyl-1,3-diisopropylisourea was obtained as a colorless oil (10.4 g, 51.9 mmol, 81% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 3.80-3.58 (1H, m, CH), 3.31-2.97 (1H, m, CH), 1.44 (9H, s, tBu), 1.19-1.01 (12H, m, Me2×2).

References

[1] Organic Letters, 2005, vol. 7, # 13, p. 2615 - 2618
[2] Chemistry - A European Journal, 2007, vol. 13, # 30, p. 8543 - 8563
[3] Beilstein Journal of Organic Chemistry, 2011, vol. 7, p. 1486 - 1493
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 10, p. 4204 - 4219
[5] Patent: EP2952517, 2015, A1. Location in patent: Paragraph 0217

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA synthesis

Synthesis of 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA from 1,2-Ethenediamine, N1,N2-bis(1-methylethyl)- and tert-Butanol

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Preparation Products And Raw materials

Raw materials

tert-Butanol N,N'-Diisopropylcarbodiimide

Preparation Products

N-1-Boc-amino-3-cyclopentene 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Suppliers

Global( 160)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Victorypharm Co.,Ltd.	+86-13916956214	sales@victory-pharm.com	China	1299	58
Suzhou Laing Biotechnology Co.,Ltd	+86-13004516015 +86-18149392822	christina@laingbiotec.com	China	777	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	12930	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29800	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Yangzhou Model Electronic Materials Co., Ltd.	+8613761402923	sales@modeltemol.com	CHINA	571	58

Supplier	Advantage
Suzhou Victorypharm Co.,Ltd.	58
Suzhou Laing Biotechnology Co.,Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Shandong chuangyingchemical Co., Ltd.	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Career Henan Chemica Co	58
Yangzhou Model Electronic Materials Co., Ltd.	58

View Lastest Price from 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-09-24	2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA 71432-55-8	US $0.00-0.00 / kg	0.1kg	98%	500kg	Suzhou Laing Biotechnology Co.,Ltd
	2019-12-26	2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA 71432-55-8	US $1.00 / KG	1KG	99%	1000KGS	Career Henan Chemical Co

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA
71432-55-8
US $0.00-0.00 / kg
98%
Suzhou Laing Biotechnology Co.,Ltd

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA
71432-55-8
US $1.00 / KG
99%
Career Henan Chemical Co

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Spectrum

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA(71432-55-8)¹HNMR

71432-55-8(2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA)Related Search:

NITRIC OXIDE 4-AMINOPHENYLBORONIC ACID HYDROCHLORIDE N,N-DIMETHYLFORMAMIDE DINEOPENTYL ACETAL O-METHYL-N,N'-DIISOPROPYLISOUREA 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA CarbaMiMidic acid, N,N'-bis(1-Methylethyl)-, 1,1-diMethylethyl ester tert-Butyl N,N'-diisopropylimidocarbamate tert-butyl N,N'-bis(1-methylethyl)imidocarbamate O-tert-Butyl-N,N'-diisopropylisourea > 3-DIISOPROPYLISOUREA 2-TERT-BUTYL-1 N,N'-bis(propan-2-yl)(tert-butoxy)methanimidamide 1,1-Dimethylethyl N,N'-bis(1-methylethyl)carbamimidate N,N'-diisopropyltert-butoxymethanimidamide 1-[(2-methylprop-2-yl)oxy]-N-(prop-2-yl)-1-(prop-2-ylamino)methanimine O-tert-Butyl-N,N'-diisopropylisourea tert-Butyl N,N'-diisopropylcarbamimidate 2-Methyl-2-propanyl N,N'-diisopropylcarbamimidate 2-Methyl-2-propanyl N,N'-diisopropylcarbamimidate O-tert-Butyl-N,N'-diisopropylisourea 71432-55-8 C11H24N2O