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ChemicalBook >> CAS DataBase List >>3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride Structure
3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride structure
CAS No.
195199-95-2
Chemical Name:
3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride
Synonyms
SB 258719;SB-258719 >=98% (HPLC);SB 258719 HYDROCHLORIDE;SB 258719, 10 mM in DMSO;Benzenesulfonamide, N,3-dimethyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-;3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride;5-HT Receptor,5-hydroxytryptamine Receptor,agonism,SB258719,Inhibitor,inverse,hydrochloride,partial,SB 258719,SB-258719,apparent,selective,inhibit,Serotonin Receptor,affinity
CBNumber:
CB82453437
Molecular Formula:
C18H30N2O2S
Molecular Weight:
338.51
MDL Number:
MFCD05662311
MOL File:
195199-95-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:34
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3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride Properties

Boiling point 463.6±55.0 °C(Predicted)
Density 1.075±0.06 g/cm3(Predicted)
storage temp. Desiccate at RT
solubility DMSO: 250 mg/mL (738.53 mM)
pka 9.36±0.10(Predicted)
form Liquid
color Light yellow to yellow
InChI 1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3
InChIKey AGVNHDNTFYHZNL-UHFFFAOYSA-N
SMILES CC1=CC=CC(S(N(C)[C@H](C)CCN2CCC(C)CC2)(=O)=O)=C1
FDA UNII GF43CP5LXQ
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1807 SB-258719 ≥98% (HPLC) 195199-95-2 5 mg $106 2026-04-30 Buy
Sigma-Aldrich SML1807 SB-258719 ≥98% (HPLC) 195199-95-2 25 mg $434 2026-04-30 Buy
Biosynth VHA19995 SB 258719 195199-95-2 25mg $1086.5 2026-06-05 Buy
Biosynth VHA19995 SB 258719 195199-95-2 50mg $1511.5 2026-06-05 Buy
Biosynth VHA19995 SB 258719 195199-95-2 100mg $2418 2026-06-05 Buy
Product number Packaging Price Buy
SML1807 5 mg $106 Buy
SML1807 25 mg $434 Buy
VHA19995 25mg $1086.5 Buy
VHA19995 50mg $1511.5 Buy
VHA19995 100mg $2418 Buy

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride Chemical Properties, Uses, Production

Uses

SB 258719 Hydrochloride is a useful intermediate.

Biological Activity

Selective 5-HT 7 receptor antagonist that displays > 100-fold selectivity over a range of other receptors. Reverses the hypothermic effect of 5-CT in mice following i.p. administration.

in vivo

SB 258719 (5-20 mg/kg; i.p.) significantly attenuates the 5-CT-induced hypothermia[2].

Animal Model:Male Swiss Webster mice (20-25 g)[2].
Dosage:5-20 mg/kg
Administration:I.p.
Result:Significantly attenuated the 5-CT-induced hypothermia.

IC 50

5-HT7 Receptor: 7.5 (pKi)

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride Suppliers

Global Suppliers ( 25)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Supplier Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 69
EMMX Biotechnology LLC 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Fan De(Beijing) Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
cjbscvictory 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from 3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SB 258719 pictures 2026-07-27 SB 258719
195199-95-2
 $50.00-166.00 99.73% 10g TargetMol Chemicals Inc.
SB 258719 pictures 2026-07-27 SB 258719
195199-95-2
 $50.00-166.00 99.73% 10g TargetMol Chemicals Inc.
  • SB 258719 pictures
  • SB 258719
    195199-95-2
  • $50.00-166.00
  • 99.73%
  • TargetMol Chemicals Inc.
  • SB 258719 pictures
  • SB 258719
    195199-95-2
  • $50.00-166.00
  • 99.73%
  • TargetMol Chemicals Inc.

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride Spectrum

3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE(195199-95-2)1HNMR

195199-95-2 (3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride) Related Search:

3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride 5-Hydroxytryptophan 3-(2,4-dimethoxybenzylidene)anabaseine Puerarin Anti-cancer compound library
VILAZODONE

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SB 258719 SB 258719 HYDROCHLORIDE Benzenesulfonamide, N,3-dimethyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]- SB-258719 >=98% (HPLC) 5-HT Receptor,5-hydroxytryptamine Receptor,agonism,SB258719,Inhibitor,inverse,hydrochloride,partial,SB 258719,SB-258719,apparent,selective,inhibit,Serotonin Receptor,affinity SB 258719, 10 mM in DMSO 3-Methyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-N-methylbenzenesulfonamide hydrochloride 195199-95-2 C18H31ClN2O2S C18H30N2O2SHCl