2-Naphthalenamine, 1,2,3,4-tetrahydro-N-2-propynyl-, hydrochloride
- CAS No.
- 134467-58-6
- Chemical Name:
- 2-Naphthalenamine, 1,2,3,4-tetrahydro-N-2-propynyl-, hydrochloride
- Synonyms
- 2-PAT;2-Naphthalenamine, 1,2,3,4-tetrahydro-N-2-propyn-1-yl-;2-Naphthalenamine, 1,2,3,4-tetrahydro-N-2-propynyl-, hydrochloride;PROP-2-YNYL-(1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-AMINE HYDROCHLORIDE
- CBNumber:
- CB82453604
- Molecular Formula:
- C13H16ClN
- Molecular Weight:
- 185.26
- MDL Number:
- MFCD09998861
- MOL File:
- 134467-58-6.mol
- MSDS File:
- SDS
2-Naphthalenamine, 1,2,3,4-tetrahydro-N-2-propynyl-, hydrochloride Chemical Properties, Uses, Production
Uses
2-PAT, an analogue of Rasagiline and Selegiline, a reversible MAO-A inhibitor with an IC50 of 0.721 μM. 2-PAT is an inactivator of MAO-B with an IC50 of 14.6 μM. 2-PAT hasthepotentialforParkinson’s disease and depressionresearch[1].
IC 50
MAO-A: 0.721 μM (IC50); MAO-B: 14.6 μM (IC50)
References
[1] Letitia Meiring, et al. The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase. Bioorg Med Chem Lett. 2022 Jul 1;67:128746. DOI:10.1016/j.bmcl.2022.128746
2-Naphthalenamine, 1,2,3,4-tetrahydro-N-2-propynyl-, hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
2-Naphthalenamine, 1,2,3,4-tetrahydro-N-2-propynyl-, hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |





