ChemicalBook >> CAS DataBase List >>KukoaMine B

KukoaMine B

KukoaMine B structure

CAS No.: 164991-67-7

Chemical Name:: KukoaMine B

Synonyms: Kukoamine B DiHCl;Geoscutin;KukoaMine B;Kukoamine B-D8;KukoaMine B (Standard);Resorcinol Impurity 30;Dihydroxybenzenepropanamide;N-(3-Aminopropyl)-3-(3,4-dihydroxyphenyl)-N-(4-((3-(3-(3,4-dihydroxyphenyl)propanamido)propyl)amino)butyl)propanamide;Benzenepropanamide,N-(3-aminopropyl)-N-[4-[[3-[[3-(3,4-dihydroxyphenyl)-1-oxopropyl]amino]propyl]amino]butyl]-3,4-dihydroxy-

CBNumber:: CB82602352

Molecular Formula:: C28H42N4O6

Molecular Weight:: 530.66

MDL Number:: MFCD29904539

MOL File:: 164991-67-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-17 09:03:53

Product description	Number	Pack Size	Price
Kukoamine B ≥95%	21091	1mg	$40
Kukoamine B ≥95%	21091	5mg	$132
Kukoamine B ≥95%	21091	10mg	$207
Kukoamine B ≥95%	21091	25mg	$423
Kukoamine B ≥95%	21091	1mg	$36
More product size

Request For Quotation

KukoaMine B Properties

Boiling point	844.3±65.0 °C(Predicted)
Density	1.232±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	-20°C
solubility	DMF:30.0(Max Conc. mg/mL);56.53(Max Conc. mM) DMSO:30.0(Max Conc. mg/mL);56.53(Max Conc. mM) Ethanol:30.0(Max Conc. mg/mL);56.53(Max Conc. mM) PBS (pH 7.2):10.0(Max Conc. mg/mL);18.84(Max Conc. mM) Water:62.5(Max Conc. mg/mL);117.78(Max Conc. mM)
form	A crystalline solid
pka	9.78±0.10(Predicted)
color	White to off-white
Major Application	food and beverages
InChIKey	IWRAOCFRRTWUDF-UHFFFAOYSA-N
SMILES	C1(CCC(N(CCCN)CCCCNCCCNC(=O)CCC2=CC=C(O)C(O)=C2)=O)=CC=C(O)C(O)=C1
FDA UNII	XZE94LC57W
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

KukoaMine B price More Price(57)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	21091	Kukoamine B ≥95%	164991-67-7	1mg	$40	2026-04-30	Buy
Cayman Chemical	21091	Kukoamine B ≥95%	164991-67-7	5mg	$132	2026-04-30	Buy
Cayman Chemical	21091	Kukoamine B ≥95%	164991-67-7	10mg	$207	2026-04-30	Buy
Cayman Chemical	21091	Kukoamine B ≥95%	164991-67-7	25mg	$423	2026-04-30	Buy
Cayman Chemical	21091	Kukoamine B ≥95%	164991-67-7	1mg	$36	2024-03-01	Buy

Product number	Packaging	Price	Buy
21091	1mg	$40	Buy
21091	5mg	$132	Buy
21091	10mg	$207	Buy
21091	25mg	$423	Buy
21091	1mg	$36	Buy

KukoaMine B Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from the bark of Lycium bark.

Uses

Kukoamine B is an amide alkaloiad used in the protection against NMDA-induced neurotoxicity and potential harmful mechanisms. In addition it is seen to inhibit the inflammatory response in the livers of septic mice.

Definition

ChEBI: Kukoamine B is an amine.

in vivo

Kukoamine B (20, 50 mg/kg, i.g., daily, 9 weeks) reduces inflammation and blood glucose without body weight gain or liver mass increase^[1].
Kukoamine B (2, 5 mg/kg, p.o., daily, 12 weeks) demonstrates the anti-osteoporotic effects in ovariectomized (OVX) mice^[3].
Kukoamine B (1.25-60 mg/kg, i.v., only one injection or very 8 h for 3 days) protects mice challenged with E. coli and reduces the circulatory levels of LPS and TNF-a in sepsis model mice^[4].

Animal Model:	Male, 4-week old db/db mice (BKS.Cgm+/+Leprdb/J) and wildtype (WT) mice (C57BLKS/J-m+/+ db). A spontaneous type 2 diabetic animal model^[1].
Dosage:	20, 50 mg/kg
Administration:	i.g., daily, 9 weeks
Result:	Successfully controlled the augment of blood glucose with age increase. Reduced levels of 29 inflammatory markers such as IL-2, IL-3, IL-4, IL-5, IL-6, IL-7 and IL8.

Animal Model:	Seven-week-old female ddy mice underwent either an ovariectomy or sham-operated surgery^[3].
Dosage:	2, 5 mg/kg
Administration:	p.o., daily, 12 weeks
Result:	Inhibited the OVX-induced BMD loss in the right femur bone and restored the impaired bone structural properties of BV/TV, Tb.Th, Tb.N, and Tb.Sp.

Animal Model:	Kunming (KM) mice, 4–6 weeks old, 18–20 g, male and female in equal number. Mice were injected with heat-killed E. coli (EC, 1.0 * 10¹¹ CFUkg_-1) in order to establish the sepsis model.^[4].
Dosage:	1.25, 2.5, 5, 10, 15, 30, 60 mg/kg
Administration:	80 mice (15, 30, 60 mg/kg), i.v., only one injection; 100 mice (1.25, 2.5, 5 mg/kg), i.v., every 8 h for 3 days; 96 mice, (60 mg/kg), i.v., once at 0, 2, 4, 6, 8 h after injection of EC.
Result:	Significantly decreased the mortality rate from 87.5% to 62.5%, 62.5%, or 37.5% (15, 30, 60 mg/kg). Decreased the mortality rate from 95% to 65%, 60% and 45% (1.25, 2.5 and 5 mg/kg). Decreased the circulatory LPS and TNF-a levels in a time-dependent manner.

KukoaMine B Preparation Products And Raw materials

Raw materials

Preparation Products

KukoaMine B Suppliers

Global( 156)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253; +8618283602253	jancyzheng@gcgreenpure.com	China	954	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	4616	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58
Aktin Chemicals, Inc.	028-85159085	info@aktinchem.com	CHINA	1025	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Henan Alfa Chemical Co., Ltd	+8615838112936	sale03@alfachem.cn	China	9804	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu Greenpure Biopharma CO.,Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
career henan chemical co	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
Hubei Ipure Biology Co., Ltd	58
Aktin Chemicals, Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Henan Alfa Chemical Co., Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from KukoaMine B manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-17	KukoaMine B 164991-67-7	$35.00-129.00		99.59%	10g	TargetMol Chemicals Inc.
	2020-01-19	Kukoamine B 164991-67-7	$3.00	1KG	99%	1kg,5kg,50kg	Career Henan Chemical Co

KukoaMine B
164991-67-7
$35.00-129.00
99.59%
TargetMol Chemicals Inc.

Kukoamine B
164991-67-7
$3.00
99%
Career Henan Chemical Co

KukoaMine B Spectrum

KukoaMine B(164991-67-7)¹HNMR

164991-67-7(KukoaMine B)Related Search:

Cevadine veratramine SCHIZANDRIN B Scutellarin menisdaurin

VERATRIDINE daurisoline L-Hyoscyamine Xanthiazone 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one

Xanthiside kukoamine A Daurinoline

1of3

KukoaMine B Benzenepropanamide,N-(3-aminopropyl)-N-[4-[[3-[[3-(3,4-dihydroxyphenyl)-1-oxopropyl]amino]propyl]amino]butyl]-3,4-dihydroxy- Kukoamine B-D8 Dihydroxybenzenepropanamide N-(3-Aminopropyl)-3-(3,4-dihydroxyphenyl)-N-(4-((3-(3-(3,4-dihydroxyphenyl)propanamido)propyl)amino)butyl)propanamide Geoscutin Resorcinol Impurity 30 KukoaMine B (Standard) Kukoamine B DiHCl 164991-67-7