3-aminopropanenitrile hydrochloride
- CAS No.
- 646-03-7
- Chemical Name:
- 3-aminopropanenitrile hydrochloride
- Synonyms
- β-Aminopropionitrile hydrochloride;3-aminopropanenitrile hydrochloride
- CBNumber:
- CB83033980
- Molecular Formula:
- C3H7ClN2
- Molecular Weight:
- 106.55
- MDL Number:
- MOL File:
- 646-03-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
3-aminopropanenitrile hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0567276 | β-Aminopropionitrile hydrochloride 99.76% | 646-03-7 | 50mg | $238 | 2026-06-04 | Buy |
| ChemScene | CS-0567276 | β-Aminopropionitrile hydrochloride 99.76% | 646-03-7 | 100mg | $379 | 2026-06-04 | Buy |
| ChemScene | CS-0567276 | β-Aminopropionitrile hydrochloride 99.76% | 646-03-7 | 250mg | $758 | 2026-06-04 | Buy |
| ChemScene | CS-0567276 | β-Aminopropionitrile hydrochloride 99.76% | 646-03-7 | 500mg | $1213 | 2026-06-04 | Buy |
| aablocks | AA006T2U | 3-Aminopropanenitrile hydrochloride 95% | 646-03-7 | 1g | $109 | 2026-05-28 | Buy |
3-aminopropanenitrile hydrochloride Chemical Properties, Uses, Production
Uses
β-Aminopropionitrile (BAPN) hydrochloride is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile hydrochloride targets the active site of LOX or LOXL isoenzymes[1][2].
in vivo
β-Aminopropionitrile (BAPN) (100 mg/kg/day; p.o.; 6 weeks) reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats[1].
β-Aminopropionitrile monofumarate (1 g/kg/day; p.o.; 4 weeks) induces thoracic aortic dissection in C57BL/6 mice[3].
| Animal Model: | Male Wistar rats of 150 g, high-fat diet (HFD) model[1] |
| Dosage: | 100 mg/kg/day |
| Administration: | In the drinking water, 6 weeks |
| Result: | Significantly prevented the rise in body weight in HFD rats, but not in animals that were fed a standard diet. Reduced the increase in the weight of white adipose tissue (both epididymal and lumbar) in obese animals and attenuated their enhanced adiposity. Improved fasted glucose and insulin levels and consequently reduced HOMA index in the HFD group. Improved insulin signalling in adipose tissue from obese animals. |
| Animal Model: | C57BL/6 mice[3] |
| Dosage: | 1 g/kg/day |
| Administration: | In the drinking water, 4 weeks |
| Result: | Induce thoracic aortic dissection (TAD) in all mice with 24h of Ang II infusion. Caused 87% of C57BL/6 mice to develop TAD without Ang II. |
IC 50
Lysyl Oxidase
References
[1] Miana M, et al. The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats. Dis Model Mech. 2015 Jun;8(6):543-51. DOI:10.1242/dmm.020107
[2] Yang X, et al. Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. Oncol Rep. 2013 Feb;29(2):541-8. DOI:10.3892/or.2012.2146
[3] Ren W, et al. β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice. Sci Rep. 2016 Jun 22;6:28149. DOI:10.1038/srep28149
3-aminopropanenitrile hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
3-aminopropanenitrile hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Wuhan WinYuanBei Trading Company | 86-13349903920 13349903920 | 869523959@qq.com | China | 9593 | 58 |
| Shaanxi Xihua Chemical Industry Co., Ltd. | 18161915376 | 1096@dideu.com | China | 2044 | 58 |
| Hainan Huaxiang Pharmaceutical Technology Co., Ltd. | -- | bug521@163.com | China | 825 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
View Latest Price from 3-aminopropanenitrile hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | β-Aminopropionitrile hydrochloride
646-03-7
|
$1520.00-2760.00 | 99.32% | 10g | TargetMol Chemicals Inc. |
-
- β-Aminopropionitrile hydrochloride
646-03-7
- $1520.00-2760.00
- 99.32%
- TargetMol Chemicals Inc.
