Tetrazine-PEG5-NHS ester
- CAS No.
- 1682653-80-0
- Chemical Name:
- Tetrazine-PEG5-NHS ester
- Synonyms
- Tetrazine-NHCO-PEG5-NHS ester;Tz-PEG5-NHS;Tetrazine-PEG5-NHS;Tetrazine-PEG4-PA-NHS;Tetrazine-PEG5-NHS ester;Tetrazine-Ph-PEG5-NHS ester;Tetrazine-PEG5-NHS ester >=95%;Tetrazine-PEG5-NHS Ester (CCT-1143);2,5-Dioxopyrrolidin-1-yl 1-(4-(1,2,4,5-tetrazin-3-yl)phenyl)-3-oxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-oate;2,5-dioxopyrrolidin-1-yl 1-({[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl}carbamoyl)-3,6,9,12,15-pentaoxaoctadecan-18-oate
- CBNumber:
- CB83062674
- Molecular Formula:
- C27H36N6O10
- Molecular Weight:
- 604.61
- MDL Number:
- MFCD28505547
- MOL File:
- 1682653-80-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Density | 1.34±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | -20°C |
| form | powder or crystals |
| pka | 14.28±0.46(Predicted) |
| color | Purple to purplish red |
| InChIKey | DUPHIQYIPUTDJS-UHFFFAOYSA-N |
| SMILES | O=C(NCC1=CC=C(C2=NN=CN=N2)C=C1)CCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
Tetrazine-PEG5-NHS ester price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 900913 | Tetrazine-PEG5-NHS ester ≥95% | 1682653-80-0 | 50MG | $429 | 2026-04-30 | Buy |
| ChemScene | CS-0109077 | Tetrazine-Ph-PEG5-NHS ester ≥97% | 1682653-80-0 | 100mg | $708 | 2026-06-04 | Buy |
| ChemScene | CS-0109077 | Tetrazine-Ph-PEG5-NHS ester ≥97% | 1682653-80-0 | 250mg | $1337 | 2026-06-04 | Buy |
| BroadPharm | bp-22681 | Tetrazine-PEG5-NHS ester 95% | 1682653-80-0 | 10MG | $173 | 2026-05-24 | Buy |
| BroadPharm | bp-22681 | Tetrazine-PEG5-NHS ester 95% | 1682653-80-0 | 25MG | $292 | 2026-05-24 | Buy |
Tetrazine-PEG5-NHS ester Chemical Properties, Uses, Production
Description
Tetrazine-PEG5-NHS Ester is a PEG linker containing a tetrazine group and an NHS ester which is very reactive with amine(NH2)-containing molecule. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).
Uses
Tetrazine-PEG5-NHS ester (Tz-PEG5-NHS) can be used in click chemistry applications such as the preparation of chitosan-polyacrylamide microspheres utilizing selective tetrazine-trans-cyclooctene (Tz-TCO) ligation and the construction of copper-64 radiolabeled antibody by the click reaction.
General Description
Tetrazine-PEG5-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and tetrazine, which is reactive to trans-cyclooctenes. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics, generally at least 10-fold faster compared to methyl substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.
reaction suitability
reaction type: click chemistry
reagent type: linker
IC 50
PEGs; Alkyl/ether
Tetrazine-PEG5-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
Tetrazine-PEG5-NHS ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Henan's chemical products co., LTD | 0371-60919097 15378766539; | 794449696@qq.com | China | 5000 | 58 |
| Zhengzhou Acme Chemical Co., Ltd. | 037163312495 13303845143 | 1416159398@qq.com | China | 10150 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1644 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1981 | 58 |
View Latest Price from Tetrazine-PEG5-NHS ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Tetrazine-PEG5-NHS ester
1682653-80-0
|
25mg | >99.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- Tetrazine-PEG5-NHS ester
1682653-80-0
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
