Tos-PEG4-CH2CO2H
- CAS No.
- 1581248-63-6
- Chemical Name:
- Tos-PEG4-CH2CO2H
- Synonyms
- Tos-PEG3-CH2COOH;Tos-PEG4-CH2CO2H;2-[2-[2-[2-(Tosyloxy)ethoxy]ethoxy]ethoxy]acetic Acid;2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]acetic acid;2-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethoxy]acetic acid;Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-
- CBNumber:
- CB83062689
- Molecular Formula:
- C15H22O8S
- Molecular Weight:
- 362.4
- MDL Number:
- MFCD27977516
- MOL File:
- 1581248-63-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Tos-PEG4-CH2CO2H price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | GNC24863 | Tos-PEG4-CH2CO2H | 1581248-63-6 | 500mg | $790 | 2026-06-04 | Buy |
| Biosynth | GNC24863 | Tos-PEG4-CH2CO2H | 1581248-63-6 | 1000mg | $1270 | 2026-06-04 | Buy |
| ChemScene | CS-0110338 | Tos-PEG3-CH2COOH ≥98% | 1581248-63-6 | 100mg | $150 | 2026-06-04 | Buy |
| ChemScene | CS-0110338 | Tos-PEG3-CH2COOH ≥98% | 1581248-63-6 | 250mg | $270 | 2026-06-04 | Buy |
| ChemScene | CS-0110338 | Tos-PEG3-CH2COOH ≥98% | 1581248-63-6 | 1g | $600 | 2026-06-04 | Buy |
Tos-PEG4-CH2CO2H Chemical Properties, Uses, Production
Description
Tos-PEG4-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
Uses
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG4-CH2CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
Tos-PEG4-CH2CO2H Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 9957 | 58 |
| Shanghai Yihe Biological Technology Co., Ltd. | 021-68882955 17721395025 | 2423903095@qq.com | China | 5000 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1978 | 58 |
| Changsha Bono New Materials Technology Co., Ltd. | 18191076804 | asherw9@hotmail.com | China | 2373 | 58 |
