Tos-PEG2-CH2CO2tBu
- CAS No.
- 1643957-24-7
- Chemical Name:
- Tos-PEG2-CH2CO2tBu
- Synonyms
- Tos-PEG1-CH2-Boc;Tos-PEG2-CH2CO2tBu;Tos-PEG1-CH2COOtBu;tert-Butyl 2-[2-(tosyloxy)ethoxy]acetate;Tert butyl 2- (2- (p-toluenesulfonyloxy) ethoxy) acetate;Acetic acid, 2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber:
- CB93062686
- Molecular Formula:
- C15H22O6S
- Molecular Weight:
- 330.4
- MDL Number:
- MFCD28122953
- MOL File:
- 1643957-24-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Tos-PEG2-CH2CO2tBu price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0105286 | Tos-PEG1-CH2-Boc ≥97% | 1643957-24-7 | 100mg | $76 | 2026-06-04 | Buy |
| ChemScene | CS-0105286 | Tos-PEG1-CH2-Boc ≥97% | 1643957-24-7 | 250mg | $110 | 2026-06-04 | Buy |
| ChemScene | CS-0105286 | Tos-PEG1-CH2-Boc ≥97% | 1643957-24-7 | 1g | $275 | 2026-06-04 | Buy |
| ChemScene | CS-0105286 | Tos-PEG1-CH2-Boc ≥97% | 1643957-24-7 | 5g | $1000 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1858 | Tos-PEG2-CH2CO2tBu 98% | 1643957-24-7 | 250mg | $504 | 2026-06-04 | Buy |
Tos-PEG2-CH2CO2tBu Chemical Properties, Uses, Production
Description
Tos-PEG2-CH2CO2tBu is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Uses
Tos-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG2-CH2CO2tBu Preparation Products And Raw materials
Raw materials
Preparation Products
Tos-PEG2-CH2CO2tBu Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Shanghai Yihe Biological Technology Co., Ltd. | 021-68882955 17721395025 | 2423903095@qq.com | China | 5000 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 9999 | 58 |
| Shanghai Maruhua Science and Technology Co. Ltd. | 18721745940 | sales2@api-chem.com | China | 1968 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5971 | 58 |
| Labnetwork lnc. | +86-27-50766799 +86-18062016861 | contact@labnetwork.com | China | 19981 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
