3-ACETYL-11-KETO-BETA-BOSWELLIC ACID
- CAS No.
- 67416-61-9
- Chemical Name:
- 3-ACETYL-11-KETO-BETA-BOSWELLIC ACID
- Synonyms
- AKBA;3-acetyl-11-keto-β-Boswellic Acid;Acetyl-11-keto-β-boswellic acid;ACETYL-11-KETO-BETA-BOSWELLIC ACID;Acetyl-11-keto-b-boswellic acid;3-ACETYL-11-KETO-B-BOSWELLIC ACID;3-O-acetyl-11-keto-β-boswellic acid;AK-BETABA;AKBA, >98%;AKBA (Standard)
- CBNumber:
- CB8309086
- Molecular Formula:
- C32H48O5
- Molecular Weight:
- 512.73
- MDL Number:
- MFCD03788777
- MOL File:
- 67416-61-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 271℃ |
|---|---|
| Boiling point | 600.3±55.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | 4.28±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| biological source | Boswellia serrata |
| Major Application | food and beverages |
| InChIKey | HMMGKOVEOFBCAU-BCDBGHSCSA-N |
| SMILES | C[C@@H]1CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CC[C@@H](OC(C)=O)[C@@](C)([C@@H]5CC[C@@]34C)C(O)=O)[C@@H]2[C@H]1C |
| LogP | 7.418 (est) |
| FDA UNII | BS16QT99Q1 |
| UNSPSC Code | 85151701 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| HS Code | 2918300000 |
| Storage Class | 11 - Combustible Solids |
3-ACETYL-11-KETO-BETA-BOSWELLIC ACID price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89153 | 3-O-Acetyl-11-keto-β-boswellic acid phyproof® Reference Substance | 67416-61-9 | 10 mg | $545 | 2026-04-30 | Buy |
| Sigma-Aldrich | A9855 | 3-Acetyl-11-keto-β-boswellic acid | 67416-61-9 | 5mg | $458 | 2026-04-30 | Buy |
| Sigma-Aldrich | 74607 | 3-O-Acetyl-11-keto-β-boswellic acid analytical standard | 67416-61-9 | 5MG | $385 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1076261 | 3-Acetyl-11-keto-β-boswellic acid United States Pharmacopeia (USP) Reference Standard | 67416-61-9 | 20mg | $744 | 2026-04-30 | Buy |
| Cayman Chemical | 11672 | 3-acetyl-11-keto-β-Boswellic Acid ≥95% | 67416-61-9 | 1mg | $41 | 2026-04-30 | Buy |
3-ACETYL-11-KETO-BETA-BOSWELLIC ACID Chemical Properties, Uses, Production
Description
3-acetyl-11-keto-β-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense). It selectively inhibits 5-lipoxygenase (IC50 = 1.5 μM) in an enzyme-directed, nonredox, and noncompetitive manner. 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.
Uses
3-Acetyl-11-keto-β-boswellic Acid (AKBA), be used in the place of the non-steroidal anti-inflammatory drug. AKBA, also inhibits human gastric carcinoma growth through modulation of the Wnt/β-catenin signaling pathway. It can be used as an anticancer agent.
Definition
ChEBI: 3-Acetyl-11-keto-beta-boswellic acid is a triterpenoid.
in vitro
akba exerted a time- and concentration -dependent cytotoxicity on androgen-independent prostate cancer cells. akba blocked proliferation and elicited apoptosis in the chemoresistant and androgen-independent human pc-3 prostate cancer cells by the release of mitochondrial cytochrome c and dna fragmentation. also, akba concentration-dependently inhibited nf-κb signaling, yet it did not directly affect the nf-κb binding to dna. additionally, akba suppressed inhibitor κb kinase and nf-κb-dependent antiapoptotic gene products in pc-3 cells [1].
in vivo
pc-3 xenotransplanted male nmri/nu-nu mice were injected intraperitoneally at 100 μmol/kg daily for three weeks. akba dampened growth and proliferation of pc-3 xenografts in nude mice and elicited apoptosis. moreover, compared with the control group, akba reduced the tumor volume and the invasiveness of the tumor into the surrounding tissues [1].
IC 50
1.5 μm
References
[1]. syrovets, t., gschwend, j., buchele, b., laumonnier, y., zugmaier, w., genze, f., & simmet, t. inhibition of iκb kinase activity by acetyl-boswellic acids promotes apoptosis in androgen-independent pc-3 prostate cancer cells in vitro and in vivo. journal of biological chemistry. 2004; 280(7): 6170-6180.
3-ACETYL-11-KETO-BETA-BOSWELLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Winherb Medical Technology Co., Ltd. | 17301719108 13341702378 | winherb@126.com | China | 1245 | 58 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
View Latest Price from 3-ACETYL-11-KETO-BETA-BOSWELLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-21 | AKBA
67416-61-9
|
$32.00-107.00 | 99.77% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-22 | Acetyl-11-Keto-β -Boswellic Acid
67416-61-9
|
1kg | 99% | 1000 kg | BINBOBIO CO., LTD. | ||
 |
2025-11-07 | boswellic acid
67416-61-9
|
$1100.00-1200.00 | 1ton | 99% | 1000T/M | Lianyungang Kaiyu Environmental Tech Co., Ltd. |
-
- AKBA
67416-61-9
- $32.00-107.00
- 99.77%
- TargetMol Chemicals Inc.
-
- Acetyl-11-Keto-β -Boswellic Acid
67416-61-9
- $0.00
- 99%
- BINBOBIO CO., LTD.
-
- boswellic acid
67416-61-9
- $1100.00-1200.00
- 99%
- Lianyungang Kaiyu Environmental Tech Co., Ltd.
