3-Hydroxypropanesulfonic acid
- CAS No.
- 15909-83-8
- Chemical Name:
- 3-Hydroxypropanesulfonic acid
- Synonyms
- 3-HYDROXYPROPANE-1-SULFONIC ACID;HPSA;Einecs 240-051-8;3-hydroxypropan-sulfonsre;Hydroxypropanesulfonicacid;3-hydroxypropan-sulfonsure;3-HydroxypropanesulfonicAci;3-Hydroxy-1-propansulfonsure;3-Hydroxypropanesulfonic acid;HYDROXYPROPANE-1-SULFONIC ACID
- CBNumber:
- CB8314428
- Molecular Formula:
- C3H8O4S
- Molecular Weight:
- 140.16
- MDL Number:
- MFCD00066499
- MOL File:
- 15909-83-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Density | 1.364 g/mL at 20 °C (lit.) |
|---|---|
| refractive index |
n |
| Flash point | 100 °C |
| storage temp. | Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 1.69±0.50(Predicted) |
| color | Light yellow to Yellow to Orange |
| BRN | 1753832 |
| InChI | 1S/C3H8O4S/c4-2-1-3-8(5,6)7/h4H,1-3H2,(H,5,6,7) |
| InChIKey | WQPMYSHJKXVTME-UHFFFAOYSA-N |
| SMILES | OCCCS(O)(=O)=O |
| FDA UNII | C667KS76K4 |
| EPA Substance Registry System | 1-Propanesulfonic acid, 3-hydroxy- (15909-83-8) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 45-21/22-35 | |||||||||
| Safety Statements | 53-26-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 1 | |||||||||
| WGK Germany | 1 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2905.59.9000 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Corr. 1 |
|||||||||
| NFPA 704 |
|
3-Hydroxypropanesulfonic acid price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 56260 | 3-Hydroxypropane-1-sulfonic acid technical, ~80% (T) | 15909-83-8 | 250ml | $469 | 2026-04-30 | Buy |
| TCI Chemical | H0597 | 3-Hydroxypropanesulfonic Acid (contains varying amounts of 3,3'-Oxydipropanesulfonic Acid)(ca. 80% in Water, ca. 7.8mol/L) | 15909-83-8 | 25g | $35 | 2026-04-30 | Buy |
| TCI Chemical | H0597 | 3-Hydroxypropanesulfonic Acid (contains varying amounts of 3,3'-Oxydipropanesulfonic Acid)(ca. 80% in Water, ca. 7.8mol/L) | 15909-83-8 | 500g | $291 | 2026-04-30 | Buy |
| Matrix Scientific | 098386 | 3-Hydroxypropane-1-sulfonic acid(75% solution in water) | 15909-83-8 | 10.00g | $125 | 2026-05-18 | Buy |
| Matrix Scientific | 098386 | 3-Hydroxypropane-1-sulfonic acid(75% solution in water) | 15909-83-8 | 500.00g | $347 | 2026-05-18 | Buy |
3-Hydroxypropanesulfonic acid Chemical Properties, Uses, Production
Uses
3-Hydroxypropanesulfonic Acid is used in preparation of Propane Sultone from Hydroxypropanesulfonic Acid.
General Description
may contain up to ~40% (NMR) 3,3′-Oxydi(propanesulfonic acid)
Synthesis
107-18-6
15909-83-8
(1) Preparation of 3-hydroxy-1-propanesulfonic acid: 1260 kg of sodium sulfite, 1040 kg of sodium bisulfite, and 1160 kg of allyl alcohol were sequentially added to the reactor at room temperature. The pH of the reaction system was precisely adjusted to 5.5 using concentrated hydrochloric acid. infrared radiation was used as the reaction induction condition. Subsequently, 126 kg of azodiisobutyronitrile was added as a catalyst and the reaction was continued for 2.5 hours. Upon completion of the reaction, 15120 L of concentrated hydrochloric acid was added to the system and the reaction was continued at 90 °C for 2 h. The reaction was carried out at 90 °C for 2.5 h. The reaction mixture was filtered to remove the salts. The reaction mixture was filtered to remove salt impurities. The filtrate was processed by extraction and phase separation was carried out using n-butanol, resulting in 280 kg of the target product 3-hydroxy-1-propanesulfonic acid.
References
[1] Justus Liebigs Annalen der Chemie, 1954, vol. 588, p. 71,78
[2] Patent: US2806876, 1954,
[3] Journal of Organic Chemistry, 1938, vol. 3, p. 186
[4] Russian Journal of Applied Chemistry, 1998, vol. 71, # 11, p. 2047 - 2048
[5] Patent: CN105348254, 2016, A. Location in patent: Paragraph 0039; 0041
3-Hydroxypropanesulfonic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| Suzhou BEC Biological Technology Co., Ltd | +86-512-68095917 17712685869 | sales@bek.com.cn | China | 142 | 59 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
View Latest Price from 3-Hydroxypropanesulfonic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-08-16 | 3-Hydroxypropanesulfonic acid
15909-83-8
|
25kg | 70% | 300 tons/year | Wuhan Hugarise New Material Co.,Ltd | ||
![]() |
2019-12-23 | 3-HYDROXYPROPANESULFONIC ACID
15909-83-8
|
$1.00 | 100g | 98%min | Career Henan Chemical Co |
-

- 3-Hydroxypropanesulfonic acid
15909-83-8
- 70%
- Wuhan Hugarise New Material Co.,Ltd
-

- 3-HYDROXYPROPANESULFONIC ACID
15909-83-8
- $1.00
- 98%min
- Career Henan Chemical Co
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