betulonic aldehyde
- CAS No.
- 4439-98-9
- Chemical Name:
- betulonic aldehyde
- Synonyms
- Betulonaldehyde;betulonic aldehyde;lup-28-al-20(29)-en-3-one;Lup-20(29)-en-28-al, 3-oxo-;Betulonic aldehyde, 97%, Semi-Synthetic;(1R,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-9-oxoicosahydro-3aH-cyclopenta[a]chrysene-3a-carbaldehyde
- CBNumber:
- CB83147203
- Molecular Formula:
- C30H46O2
- Molecular Weight:
- 438.69
- MDL Number:
- MFCD11707369
- MOL File:
- 4439-98-9.mol
- MSDS File:
- SDS
betulonic aldehyde price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 33042 | Betulonaldehyde ≥95% | 4439-98-9 | 10mg | $174 | 2026-04-30 | Buy |
| Cayman Chemical | 33042 | Betulonaldehyde ≥95% | 4439-98-9 | 50mg | $734 | 2026-04-30 | Buy |
| Cayman Chemical | 33042 | Betulonaldehyde ≥95% | 4439-98-9 | 100mg | $1293 | 2026-04-30 | Buy |
| Biosynth | EAA43998 | Betulonic aldehyde | 4439-98-9 | 5mg | $250 | 2026-06-04 | Buy |
| Biosynth | EAA43998 | Betulonic aldehyde | 4439-98-9 | 10mg | $251.3 | 2026-06-04 | Buy |
betulonic aldehyde Chemical Properties,Uses,Production
Uses
Betulonaldehyde is a pentacyclic triterpenoid that can be isolated from Diospyros filipendula. Betulonaldehyde has antiplasmodial activity (IC50: 3.36μg/mL). Betulonaldehyde has cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s: 19.23 and 17.09 μg/mL, respectively). Betulonaldehyde inhibits Phorbol 12-myristate 13-acetate (HY-18739) induced inflammation in mice[1][2].
Biological Activity
Betulonaldehyde is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in Betula.1 It is active against P. falciparum (IC50 = 3.36 μg/ml) and cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s = 19.23 and 17.09 μg/ml, respectively).2 Topical application of betulonaldehyde (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate in mice.3 It has also been used a precursor in the semisynthesis of C-2 and C-28 betulonic aldehyde derivatives.1
References
1.Ayers, S., Benkovics, T., Marshall, J., et al.Autoxidation products of betulonaldehydeJ. Nat. Prod.79(10)2758-2761(2016) 2.Wisetsai, A., Schevenels, F.T., and Lekphrom, R.Chemical constituents and their biological activities from the roots of diospyros filipendulaNat. Prod. Res.1-5(2019) 3.Yasukawa, K., Yu, S., Yamanouchi, S., et al.Some lupane-type triterpenes inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skinPhytomedicine1(4)309-313(1995)
betulonic aldehyde Preparation Products And Raw materials
betulonic aldehyde Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dezhou LonWel Pharmaceutical Technology Co., Ltd. | 13761310616 | 39324283@qq.com | China | 1360 | 58 |
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| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 10763 | 58 |
