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Lupenone

CAS No.
1617-70-5
Chemical Name:
Lupenone
Synonyms
Lup-20(29)-en-3-one;Lupenone;-en-3-one;Aids082905;Lup-20(29);Aids-082905;LUPENONE(RG);18-LUPEN-3-ONE;Lupa-20(30)-ene-3-one;Lupa-20(29)-ene-3β-one
CBNumber:
CB3447619
Molecular Formula:
C30H48O
Molecular Weight:
424.7
MDL Number:
MFCD00083578
MOL File:
1617-70-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:03

Lupenone Properties

Melting point 165-167°C
Boiling point 485.7±14.0 °C(Predicted)
Density 1.115 g/cm3(Temp: 18 °C)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White
LogP 10.400 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
HS Code  29142990

Lupenone price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R205265 LUP-20(29)-EN-3-ONE AldrichCPR 1617-70-5 1MG $121 2026-04-30 Buy
Cayman Chemical 35335 Lupenone ≥98% 1617-70-5 5mg $248 2026-04-30 Buy
Cayman Chemical 35335 Lupenone ≥98% 1617-70-5 10mg $471 2026-04-30 Buy
Cayman Chemical 35335 Lupenone ≥98% 1617-70-5 25mg $1052 2026-04-30 Buy
TRC TRC-L474840-2.5MG Lupenone 1617-70-5 2.5mg $218 2026-06-03 Buy
Product number Packaging Price Buy
R205265 1MG $121 Buy
35335 5mg $248 Buy
35335 10mg $471 Buy
35335 25mg $1052 Buy
TRC-L474840-2.5MG 2.5mg $218 Buy

Lupenone Chemical Properties, Uses, Production

Chemical Properties

White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dandelion, bamboo leaves and Adenophora australis.

Uses

Lupenone is a lupane triterpenoid with antioxidant and anticholinesterase activity. It also a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor.

Definition

ChEBI: A natural product found in Cupania cinerea.

in vivo

Lupenone (6, 12, 24 mg/kg/day, gavage for 6 weeks) improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/ CTGF-related fibrosis[2].

Animal Model:Spontaneous type 2 diabetic nephropathy db/db mouse models[1]
Dosage:6, 12, 24 mg/kg
Administration:i.g.
Result:Maintained the fasting blood glucose.
Reduced glycosylated hemoglobin, insulin, and 24 h proteinuria levels.
Regulated changes in biochemical indicators

IC 50

Trypanosoma

Lupenone Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 132)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
ShangHai YuanYe Biotechnology Co., Ltd. 15026964105 shyysw007@163.com China 4998 60
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130 3423497944@qq.com China 8135 55

View Latest Price from Lupenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LUPENONE pictures 2026-07-27 LUPENONE
1617-70-5
$55.00-197.00 99.92% 10g TargetMol Chemicals Inc.
LUPENONE pictures 2019-07-06 LUPENONE
1617-70-5
$1.00 1 mg 99% 100KG Career Henan Chemical Co
  • LUPENONE pictures
  • LUPENONE
    1617-70-5
  • $55.00-197.00
  • 99.92%
  • TargetMol Chemicals Inc.
  • LUPENONE pictures
  • LUPENONE
    1617-70-5
  • $1.00
  • 99%
  • Career Henan Chemical Co
Aids-082905 18-LUPEN-3-ONE -en-3-one Lup-20(29) LUPENONE(RG) 5α-Lup-20(29)-en-3-one Lupa-20(29)-ene-3β-one Lupa-20(30)-ene-3-one (1R,3Ar,4S,5ar,5br,7ar,11ar,11br,13ar,13br)-1-isopropenyl-3A,5A,5B,8,8,11A-hexamethyl-eicosahydro-cyclopenta[A]chrysen-9-one Aids082905 (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysen-9-one (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-Hexamethyl-1-(prop-1-en-2-yl)icosahydro-9H-cyclopenta[a]chrysen-9-one Lup-20(29)-en-3-one Lupenone (1 mg/mL in Ethyl Acetate) Lupenone 1617-70-5 1657-70-5 Building block