Lupenone
- CAS No.
- 1617-70-5
- Chemical Name:
- Lupenone
- Synonyms
- Lup-20(29)-en-3-one;Lupenone;-en-3-one;Aids082905;Lup-20(29);Aids-082905;LUPENONE(RG);18-LUPEN-3-ONE;Lupa-20(30)-ene-3-one;Lupa-20(29)-ene-3β-one
- CBNumber:
- CB3447619
- Molecular Formula:
- C30H48O
- Molecular Weight:
- 424.7
- MDL Number:
- MFCD00083578
- MOL File:
- 1617-70-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| HS Code | 29142990 |
Lupenone price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R205265 | LUP-20(29)-EN-3-ONE AldrichCPR | 1617-70-5 | 1MG | $121 | 2026-04-30 | Buy |
| Cayman Chemical | 35335 | Lupenone ≥98% | 1617-70-5 | 5mg | $248 | 2026-04-30 | Buy |
| Cayman Chemical | 35335 | Lupenone ≥98% | 1617-70-5 | 10mg | $471 | 2026-04-30 | Buy |
| Cayman Chemical | 35335 | Lupenone ≥98% | 1617-70-5 | 25mg | $1052 | 2026-04-30 | Buy |
| TRC | TRC-L474840-2.5MG | Lupenone | 1617-70-5 | 2.5mg | $218 | 2026-06-03 | Buy |
Lupenone Chemical Properties, Uses, Production
Chemical Properties
White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dandelion, bamboo leaves and Adenophora australis.
Uses
Lupenone is a lupane triterpenoid with antioxidant and anticholinesterase activity. It also a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor.
Definition
ChEBI: A natural product found in Cupania cinerea.
in vivo
Lupenone (6, 12, 24 mg/kg/day, gavage for 6 weeks) improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/ CTGF-related fibrosis[2].
| Animal Model: | Spontaneous type 2 diabetic nephropathy db/db mouse models[1] |
| Dosage: | 6, 12, 24 mg/kg |
| Administration: | i.g. |
| Result: | Maintained the fasting blood glucose. Reduced glycosylated hemoglobin, insulin, and 24 h proteinuria levels. Regulated changes in biochemical indicators |
IC 50
Trypanosoma
Lupenone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
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