Methyl 3-methoxysalicylate
- CAS No.
- 6342-70-7
- Chemical Name:
- Methyl 3-methoxysalicylate
- Synonyms
- AKOS 214-56;RARECHEM AL BF 0033;METHYL 3-METHOXYSALICYLATE;Methyl 2-Hydroxy-m-anisate;Methyl3-Methoxysalicylate>METHYL 2-HYDROXY-3-METHOXY-BENZOATE;2-Hydroxy-m-anisic Acid Methyl Ester;3-Methoxysalicylic Acid Methyl Ester;2-HYDROXY-3-METHOXYBENZOIC ACID METHYL ESTER;Benzoic acid, 2-hydroxy-3-methoxy-, methyl ester
- CBNumber:
- CB8314842
- Molecular Formula:
- C9H10O4
- Molecular Weight:
- 182.17
- MDL Number:
- MFCD00239511
- MOL File:
- 6342-70-7.mol
- MSDS File:
- SDS
| Melting point | 65-68 °C (lit.) |
|---|---|
| Boiling point | 105 °C(Press: 2 Torr) |
| Density | 1.216±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 9.76±0.10(Predicted) |
| color | White to Gray to Red |
| λmax | 320nm(Dioxane)(lit.) |
| InChI | InChI=1S/C9H10O4/c1-12-7-5-3-4-6(8(7)10)9(11)13-2/h3-5,10H,1-2H3 |
| InChIKey | BWRCJLJJIXYLNV-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC=CC(OC)=C1O |
| CAS DataBase Reference | 6342-70-7(CAS DataBase Reference) |
| FDA UNII | P453VWE7LY |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HS Code | 29189900 |
Methyl 3-methoxysalicylate price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 449490 | Methyl 3-methoxysalicylate 98% | 6342-70-7 | 10g | $686 | 2023-01-07 | Buy |
| TCI Chemical | M2167 | Methyl 3-Methoxysalicylate >98.0%(GC) | 6342-70-7 | 5g | $85 | 2025-07-31 | Buy |
| TCI Chemical | M2167 | Methyl 3-Methoxysalicylate >98.0%(GC) | 6342-70-7 | 25g | $254 | 2025-07-31 | Buy |
| TRC | M323653 | Methyl2-Hydroxy-3-methoxybenzoate | 6342-70-7 | 500mg | $45 | 2021-12-16 | Buy |
| TRC | M323653 | Methyl2-Hydroxy-3-methoxybenzoate | 6342-70-7 | 1g | $60 | 2021-12-16 | Buy |
Methyl 3-methoxysalicylate Chemical Properties,Uses,Production
Synthesis
67-56-1
877-22-5
6342-70-7
General procedure for the synthesis of methyl 2-hydroxy-3-methoxybenzoate from methanol and 3-methoxysalicylic acid: 25.5 g (0.152 mol) of 3-methoxysalicylic acid was added to 250 ml of methanol containing 1 ml of concentrated sulfuric acid. The reaction mixture was heated to reflux for 4 days. After completion of the reaction, the mixture was concentrated to dryness. The concentrate was extracted with ethyl acetate. The organic layer was washed sequentially with water, 10% sodium carbonate solution, water and saturated sodium chloride solution. After the above treatment, 25.2 g of the target product methyl 2-hydroxy-3-methoxybenzoate was obtained in 91.2% yield. The melting point was 68-69°C.
References
[1] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 9, p. 1447 - 1456
[2] Patent: KR2018/56603, 2018, A. Location in patent: Paragraph 0441; 0453-0455
[3] Australian Journal of Chemistry, 2003, vol. 56, # 11, p. 1099 - 1106
[4] Synthetic Communications, 1995, vol. 25, # 6, p. 915 - 920
[5] Journal of Medicinal Chemistry, 1991, vol. 34, # 5, p. 1612 - 1624
Methyl 3-methoxysalicylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12398 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29733 | 60 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29801 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1087@dideu.com | China | 3947 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
View Lastest Price from Methyl 3-methoxysalicylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-08 | Methyl 3-methoxysalicylate
6342-70-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-27 | Methyl 3-methoxysalicylate
6342-70-7
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-06-20 | Methyl 3-methoxysalicylate
6342-70-7
|
US $10.00-1.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Methyl 3-methoxysalicylate
6342-70-7
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- Methyl 3-methoxysalicylate
6342-70-7
- US $0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Methyl 3-methoxysalicylate
6342-70-7
- US $10.00-1.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
