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Methyl 3-methoxysalicylate

Methyl 3-methoxysalicylate structure

CAS No.: 6342-70-7

Chemical Name:: Methyl 3-methoxysalicylate

Synonyms: AKOS 214-56;RARECHEM AL BF 0033;METHYL 3-METHOXYSALICYLATE;Methyl 2-Hydroxy-m-anisate;Methyl3-Methoxysalicylate>METHYL 2-HYDROXY-3-METHOXY-BENZOATE;2-Hydroxy-m-anisic Acid Methyl Ester;3-Methoxysalicylic Acid Methyl Ester;2-HYDROXY-3-METHOXYBENZOIC ACID METHYL ESTER;Benzoic acid, 2-hydroxy-3-methoxy-, methyl ester

CBNumber:: CB8314842

Molecular Formula:: C9H10O4

Molecular Weight:: 182.17

MDL Number:: MFCD00239511

MOL File:: 6342-70-7.mol

MSDS File:: SDS

Last updated:2026-01-13 11:26:29

Product description	Number	Pack Size	Price
Methyl 3-methoxysalicylate 98%	449490	10g	$686
Methyl 3-Methoxysalicylate >98.0%(GC)	M2167	5g	$68
Methyl 3-Methoxysalicylate >98.0%(GC)	M2167	25g	$203
Methyl2-Hydroxy-3-methoxybenzoate	M323653	5g	$75
Methyl2-Hydroxy-3-methoxybenzoate	M323653	500mg	$45
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Methyl 3-methoxysalicylate Properties

Melting point	65-68 °C (lit.)
Boiling point	105 °C(Press: 2 Torr)
Density	1.216±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	9.76±0.10(Predicted)
form	powder to crystal
color	White to Gray to Red
λmax	320nm(Dioxane)(lit.)
InChI	InChI=1S/C9H10O4/c1-12-7-5-3-4-6(8(7)10)9(11)13-2/h3-5,10H,1-2H3
InChIKey	BWRCJLJJIXYLNV-UHFFFAOYSA-N
SMILES	C(OC)(=O)C1=CC=CC(OC)=C1O
CAS DataBase Reference	6342-70-7(CAS DataBase Reference)
FDA UNII	P453VWE7LY
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	29189900
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

Methyl 3-methoxysalicylate price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	449490	Methyl 3-methoxysalicylate 98%	6342-70-7	10g	$686	2023-01-07	Buy
TCI Chemical	M2167	Methyl 3-Methoxysalicylate >98.0%(GC)	6342-70-7	5g	$68	2026-03-19	Buy
TCI Chemical	M2167	Methyl 3-Methoxysalicylate >98.0%(GC)	6342-70-7	25g	$203	2026-03-19	Buy
TRC	M323653	Methyl2-Hydroxy-3-methoxybenzoate	6342-70-7	5g	$75	2021-12-16	Buy
TRC	M323653	Methyl2-Hydroxy-3-methoxybenzoate	6342-70-7	500mg	$45	2021-12-16	Buy

Product number	Packaging	Price	Buy
449490	10g	$686	Buy
M2167	5g	$68	Buy
M2167	25g	$203	Buy
M323653	5g	$75	Buy
M323653	500mg	$45	Buy

Methyl 3-methoxysalicylate Chemical Properties,Uses,Production

Synthesis

67-56-1

877-22-5

6342-70-7

General procedure for the synthesis of methyl 2-hydroxy-3-methoxybenzoate from methanol and 3-methoxysalicylic acid: 25.5 g (0.152 mol) of 3-methoxysalicylic acid was added to 250 ml of methanol containing 1 ml of concentrated sulfuric acid. The reaction mixture was heated to reflux for 4 days. After completion of the reaction, the mixture was concentrated to dryness. The concentrate was extracted with ethyl acetate. The organic layer was washed sequentially with water, 10% sodium carbonate solution, water and saturated sodium chloride solution. After the above treatment, 25.2 g of the target product methyl 2-hydroxy-3-methoxybenzoate was obtained in 91.2% yield. The melting point was 68-69°C.

References

[1] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 9, p. 1447 - 1456
[2] Patent: KR2018/56603, 2018, A. Location in patent: Paragraph 0441; 0453-0455
[3] Australian Journal of Chemistry, 2003, vol. 56, # 11, p. 1099 - 1106
[4] Synthetic Communications, 1995, vol. 25, # 6, p. 915 - 920
[5] Journal of Medicinal Chemistry, 1991, vol. 34, # 5, p. 1612 - 1624

Methyl 3-methoxysalicylate Preparation Products And Raw materials

Raw materials

Methanol 3-Methoxysalicylic acid

Preparation Products

LY 294002 Hydrochloride 3-ISOPROPYLCATECHOL Methyl 5-allyl-3-methoxysalicylate 2-HYDROXY-3-METHOXYBENZAMIDE

Methyl 3-methoxysalicylate Suppliers

Global( 155)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	904	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569262 +86-15003564040	1056@dideu.com	China	3982	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Nanjing Hengbei Chemicals Co., Ltd.	025-58393656 18913958656	sales@hengbeichem.cn	China	6854	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Arbor Chemical Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nanjing Hengbei Chemicals Co., Ltd.	58

View Lastest Price from Methyl 3-methoxysalicylate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-06-27	Methyl 3-methoxysalicylate 6342-70-7	US $0.00 / KG	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd
2025-06-20	Methyl 3-methoxysalicylate 6342-70-7	US $10.00-1.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.
2020-01-08	Methyl 3-methoxysalicylate 6342-70-7	US $3.00 / KG	1IU	98%	200KG	Career Henan Chemical Co

Methyl 3-methoxysalicylate
6342-70-7
US $0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Methyl 3-methoxysalicylate
6342-70-7
US $10.00-1.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

Methyl 3-methoxysalicylate
6342-70-7
US $3.00 / KG
98%
Career Henan Chemical Co

Methyl 3-methoxysalicylate Spectrum

Methyl 3-methoxysalicylate(6342-70-7)¹HNMR

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METHYL 3-METHOXYSALICYLATE METHYL 2-HYDROXY-3-METHOXY-BENZOATE 2-HYDROXY-3-METHOXYBENZOIC ACID METHYL ESTER AKOS 214-56 RARECHEM AL BF 0033 Methyl 3-methoxysalicylate,Methyl 2-hydroxy-3-methoxybenzoate 3-Methoxysalicylic Acid Methyl Ester Methyl 2-Hydroxy-3-methoxybenzoate 2-Hydroxy-3-methoxybenzoic Acid Methyl Ester Methyl 2-Hydroxy-m-anisate 2-Hydroxy-m-anisic Acid Methyl Ester Methyl3-Methoxysalicylate> Benzoic acid, 2-hydroxy-3-methoxy-, methyl ester 3-Methoxysalicylic Acid Methyl Ester 2-Hydroxy-m-anisic Acid Methyl Ester Methyl 2-Hydroxy-m-anisate 6342-70-7 Esters Organic Building Blocks Building Blocks C8 to C9 Carbonyl Compounds Aromatic Esters Building Blocks C8 to C9 Carbonyl Compounds Chemical Synthesis Esters Organic Building Blocks Acids and Derivatives Alcohols and Derivatives