ML311
- CAS No.
- 315698-17-0
- Chemical Name:
- ML311
- Synonyms
- ML311;Mcl-1 Inhibitor II;ML311, 10 mM in DMSO;ML 311,Inhibitor,ML-311,Bcl-2 Family,ML311,inhibit;7-((4-Ethylpiperazin-1-yl)(4-(trifluoromethyl)phenyl)methyl)quinolin-8-ol;7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol;2-((4-ethylpiperazin-1-yl)(4-(trifluoromethyl)phenyl)methyl)naphthalen-1-ol;8-Quinolinol, 7-[(4-ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-;7-((4-Ethylpiperazin-1-yl)(4-(trifluoromethyl)phenyl)methyl)quinolin-8-ol , ML311
- CBNumber:
- CB83166378
- Molecular Formula:
- C23H24F3N3O
- Molecular Weight:
- 415.45
- MDL Number:
- MFCD02330695
- MOL File:
- 315698-17-0.mol
- MSDS File:
- SDS
| Melting point | >94*C (dec.) |
|---|---|
| Boiling point | 515.7±45.0 °C(Predicted) |
| Density | 1.268±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.38±0.50(Predicted) |
| form | Solid |
| color | Yellow |
| InChIKey | NGAPBLRRJSKIRT-UHFFFAOYSA-N |
| SMILES | FC(F)(F)c1ccc(cc1)C(N4CCN(CC4)CC)c2c(c3ncccc3cc2)O |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
ML311 price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29445 | ML-311 ≥98% | 315698-17-0 | 1mg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 29445 | ML-311 ≥98% | 315698-17-0 | 5mg | $128 | 2026-04-30 | Buy |
| Cayman Chemical | 29445 | ML-311 ≥98% | 315698-17-0 | 10mg | $196 | 2026-04-30 | Buy |
| Biosynth | QMA69817 | ML-311 | 315698-17-0 | 50mg | $2921.5 | 2026-06-04 | Buy |
| Biosynth | QMA69817 | ML-311 | 315698-17-0 | 0.5g | $7994.5 | 2026-06-04 | Buy |
ML311 Chemical Properties, Uses, Production
Uses
7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol is a selective inhibitor of the protein -protein interaction of Mcl-1 inhibitors and also a potential antitumor agents. Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
Biological Activity
Cell permeable: yes', 'Primary Target
Mcl-1', 'Reversible: yes
IC 50
Mcl-1; Bim
storage
Store at -20°C
ML311 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4860 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4058 | 58 |
| Changzhou Xuanye Technology Co., Ltd | 15195022192; | 279776773@qq.com | China | 1999 | 58 |
