(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid
- CAS No.
- 1247879-16-8
- Chemical Name:
- (S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid
- Synonyms
- CYCLUC1;Luciferase substrate;CycLuc1, 10 mM in DMSO;CycLuc1(Luciferase substrate);Luciferase Substrate, CycLuc1;CycLuc 1,inhibit,CycLuc1,Reactive Oxygen Species,Inhibitor,CycLuc-1;(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid;CycLuc1 (R)-2-(6,7-dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole- 4-carboxylic acid;Cyluc1 [(4S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydro-thiazole-4-carboxylic acid];4-Thiazolecarboxylic acid, 2-(6,7-dihydro-5H-pyrrolo[3,2-f]benzothiazol-2-yl)-4,5-dihydro-, (4S)-
- CBNumber:
- CB83358296
- Molecular Formula:
- C13H11N3O2S2
- Molecular Weight:
- 305.38
- MDL Number:
- MFCD28133582
- MOL File:
- 1247879-16-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 606.8±65.0 °C(Predicted) |
|---|---|
| Density | 1.84±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 83.33 mg/mL (272.87 mM) |
| pka | 3.54±0.20(Predicted) |
| form | Solid |
| color | Yellow to brown |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 5.30650 | Luciferase Substrate, CycLuc1 | 10mg | $344 | 2026-04-30 | Buy | |
| ChemScene | CS-0089228 | CycLuc1 99.72% | 1247879-16-8 | 5mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-0089228 | CycLuc1 99.72% | 1247879-16-8 | 10mg | $87 | 2026-06-04 | Buy |
| ChemScene | CS-0089228 | CycLuc1 99.72% | 1247879-16-8 | 25mg | $173 | 2026-06-04 | Buy |
| ChemScene | CS-0089228 | CycLuc1 99.72% | 1247879-16-8 | 50mg | $303 | 2026-06-04 | Buy |
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid Chemical Properties, Uses, Production
Uses
Luciferase Substrate, CycLuc1 has been used for transfecting HEK293 cells to study the inhibition of intracellular luciferase crystallization by D-luciferin and its synthetic analogues.
Biological Activity
Cell permeable: yes', 'Primary Target
Luciferase
in vivo
CycLuc1 (0.05-5 mM, intraperitoneally injected) can improve bioluminescence imaging (BLI) of the existing luciferase reporter protein in mice and achieve brain imaging that D-luciferin cannot achieve[2].
| Animal Model: | Mouse xenograft tumor models[2] |
| Dosage: | 0.05, 0.5, 1, 5 mM, 100 μL |
| Administration: | i.p. |
| Result: | Yielded a >10-fold higher bioluminescent signal than could be obtained from D-luciferin injection at equivalent doses. |
storage
Store at -20°C
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003;025-846993838003-8003 18013301590 | njduly@126.com | China | 3293 | 55 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4859 | 55 | |
| Struchem Co., Ltd. | 0512-63009836 18994340901 | helen@struchem.com | China | 3968 | 60 |
| AOKBIO Inc. | 021-68712331 3286104197 | China | 321 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |






