(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid

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(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid manufacturers

  • CycLuc1
  • CycLuc1 pictures
  • $40.00
  • 2026-07-15
  • CAS:1247879-16-8
  • Purity: 99.07%
  • Supply Ability: 10g
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid Basic information
Product Name:(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid
Synonyms:Cyluc1 [(4S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydro-thiazole-4-carboxylic acid];CycLuc1(Luciferase substrate);Luciferase substrate;4-Thiazolecarboxylic acid, 2-(6,7-dihydro-5H-pyrrolo[3,2-f]benzothiazol-2-yl)-4,5-dihydro-, (4S)-;CycLuc1 (R)-2-(6,7-dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole- 4-carboxylic acid;CycLuc 1,inhibit,CycLuc1,Reactive Oxygen Species,Inhibitor,CycLuc-1;Luciferase Substrate, CycLuc1;CycLuc1, 10 mM in DMSO
CAS:1247879-16-8
MF:C13H11N3O2S2
MW:305.38
EINECS:
Product Categories:
Mol File:1247879-16-8.mol
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid Structure
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid Chemical Properties
Boiling point 606.8±65.0 °C(Predicted)
density 1.84±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 83.33 mg/mL (272.87 mM)
pka3.54±0.20(Predicted)
form Solid
color Yellow to brown
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid Usage And Synthesis
UsesLuciferase Substrate, CycLuc1 has been used for transfecting HEK293 cells to study the inhibition of intracellular luciferase crystallization by D-luciferin and its synthetic analogues.
Biological ActivityCell permeable: yes', 'Primary Target
Luciferase
in vivo

CycLuc1 (0.05-5 mM, intraperitoneally injected) can improve bioluminescence imaging (BLI) of the existing luciferase reporter protein in mice and achieve brain imaging that D-luciferin cannot achieve[2].

Animal Model:Mouse xenograft tumor models[2]
Dosage:0.05, 0.5, 1, 5 mM, 100 μL
Administration:i.p.
Result:Yielded a >10-fold higher bioluminescent signal than could be obtained from D-luciferin injection at equivalent doses.
storageStore at -20°C
(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid Preparation Products And Raw materials
Tag:(S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid(1247879-16-8) Related Product Information
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