CHAETOGLOBOSIN A
- CAS No.
- 50335-03-0
- Chemical Name:
- CHAETOGLOBOSIN A
- Synonyms
- CHAETOGLOBOSIN;CHAETOGLOBOSINL;CHAETOGLOBOSINE;CHAETOGLOBOSINM;CHAETOGLOBOSINB;chaetoglobosins;Chaetogloboin A;CHAETOGLOBOSIN A;Chaetoglobosin A, Antibiotic agent;CHAETOGLOBOSIN A, B, C, D, E, F, K, Q, R, T
- CBNumber:
- CB8359122
- Molecular Formula:
- C32H36N2O5
- Molecular Weight:
- 528.64
- MDL Number:
- MFCD31380758
- MOL File:
- 50335-03-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Chaetoglobosin A ≥98% (HPLC) | SML0642 | 1mg | $408 |
| Chaetoglobosin A ≥98% | 19405 | 1mg | $125 |
| Chaetoglobosin A ≥98% | 19405 | 5mg | $464 |
| Chaetoglobosin A (NSC366739, BRN1097707) ≥98%(HPLC) | 207113 | 1mg | $303 |
| Chaetoglobosin A (NSC366739, BRN1097707) ≥98%(HPLC) | 207113 | 5mg | $505 |
| More product size | |||
| Melting point | 188°C |
|---|---|
| Boiling point | 608.81°C (rough estimate) |
| Density | 1.1705 (rough estimate) |
| refractive index | 1.5800 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: soluble10mg/mL |
| pka | 17.32±0.30(Predicted) |
| form | solid |
| color | Yellow |
| biological source | Chaetomium globosum |
| Stability | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| InChIKey | OUMWCYMRLMEZJH-VIRVUJSBSA-N |
| SMILES | [nH]1c2c(c(c1)C[C@@H]3NC(=O)[C@]54[C@H]3[C@@H]([C@]6(O[C@H]6C5\C=C\C[C@@H](\C=C(\[C@H](C(=O)\C=C\C4=O)O)/C)C)C)C)cccc2 |
| FDA UNII | 73AYL68TNX |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280-P261 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2941900000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
CHAETOGLOBOSIN A price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0642 | Chaetoglobosin A ≥98% (HPLC) | 50335-03-0 | 1mg | $408 | 2025-07-31 | Buy |
| Cayman Chemical | 19405 | Chaetoglobosin A ≥98% | 50335-03-0 | 1mg | $125 | 2026-04-30 | Buy |
| Cayman Chemical | 19405 | Chaetoglobosin A ≥98% | 50335-03-0 | 5mg | $464 | 2026-04-30 | Buy |
| Usbiological | 207113 | Chaetoglobosin A (NSC366739, BRN1097707) ≥98%(HPLC) | 50335-03-0 | 1mg | $303 | 2026-06-03 | Buy |
| Usbiological | 207113 | Chaetoglobosin A (NSC366739, BRN1097707) ≥98%(HPLC) | 50335-03-0 | 5mg | $505 | 2026-06-03 | Buy |
CHAETOGLOBOSIN A Chemical Properties,Uses,Production
Description
Chaetoglobosin A (50335-03-0) is a cytochalasin analog which targets filamentous actin. Displays cytotoxic effects against human colorectal HCT116 cells, IC50=3.15 μM.1 Preferentially induces apoptosis in chronic lymphocytic leukemia cells via targeting the cytoskeleton.2 Enhances the fibrinolytic activity of vascular endothelial cells.3
Occurrence
A complex macrocyclic alkaloid, this base has been isolated from Diplodia rnacrospora. Chaetoglobosin A possesses the property of inhibiting growth in wheat coleoptiles.
Uses
Chaetoglobosin A is a mycotoxic cytochalasan compound.
Definition
ChEBI: A cytochalasan alkaloid isolated from Chaetomium globosum and Calonectria morganii.
storage
+4°C
References
[1] HE LI. Chaetoglobosins from Chaetomium globosum, an Endophytic Fungus in Ginkgo biloba, and Their Phytotoxic and Cytotoxic Activities[J]. Journal of Agricultural and Food Chemistry, 2014, 62 17: 3734-3741. DOI:10.1021/jf500390h
[2] P B KNUDSEN. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton[J]. Leukemia, 2013, 28 6: 1289-1298. DOI:10.1038/leu.2013.360
[3] C SHINOHARA. Enhancement of fibrinolytic activity of vascular endothelial cells by chaetoglobosin A, crinipellin B, geodin and triticone B.[J]. Journal of Antibiotics, 2000, 53 3: 262-268. DOI:10.7164/antibiotics.53.262
CHAETOGLOBOSIN A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52906 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40048 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Shanghai Haozhixiang Biotechnology Co., Ltd | 526763801 13301653310 | 526763801@qq.com | China | 9549 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 29654 | 68 |
View Lastest Price from CHAETOGLOBOSIN A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | Chaetoglobosin A
50335-03-0
|
$458.00-1700.00 | 10g | TargetMol Chemicals Inc. |
-
- Chaetoglobosin A
50335-03-0
- $458.00-1700.00
- TargetMol Chemicals Inc.
