Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>5,6-Methylenedioxyindole

5,6-Methylenedioxyindole

5,6-Methylenedioxyindole Structure
5,6-Methylenedioxyindole structure
CAS No.
267-48-1
Chemical Name:
5,6-Methylenedioxyindole
Synonyms
5,6-METHYLENEDIOXYINDOLE;5h-1,3-dioxolo(4,5-f)indole;5H-[1,3]dioxolo[4,5-f]indol;5-6-methylenedioxyindole tan crystals;5H-[1,3]Dioxolo[4,5-f]indole - [D71752]
CBNumber:
CB8359278
Molecular Formula:
C9H7NO2
Molecular Weight:
161.16
MDL Number:
MFCD00046910
MOL File:
267-48-1.mol
MSDS File:
SDS
Last updated:2026-05-28 03:21:27
Request For Quotation

5,6-Methylenedioxyindole Properties

Melting point 110 °C
Boiling point 334.7±11.0 °C(Predicted)
Density 1.425±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 16.93±0.20(Predicted)
color tan
EWG's Food Scores 1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P280
Risk Statements  20/21/22
Safety Statements  36
WGK Germany  3
RTECS  JI4650000

5,6-Methylenedioxyindole price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix D71752 5H-[1,3]Dioxolo[4,5-f]indole 97% 267-48-1 250mg $17 2026-05-06 Buy
Synthonix D71752 5H-[1,3]Dioxolo[4,5-f]indole 97% 267-48-1 1g $20 2026-05-06 Buy
Synthonix D71752 5H-[1,3]Dioxolo[4,5-f]indole 97% 267-48-1 5g $40 2026-05-06 Buy
Synthonix D71752 5H-[1,3]Dioxolo[4,5-f]indole 97% 267-48-1 10g $80 2026-05-06 Buy
Synthonix D71752 5H-[1,3]Dioxolo[4,5-f]indole 97% 267-48-1 25g $190 2026-05-06 Buy
Product number Packaging Price Buy
D71752 250mg $17 Buy
D71752 1g $20 Buy
D71752 5g $40 Buy
D71752 10g $80 Buy
D71752 25g $190 Buy

5,6-Methylenedioxyindole Chemical Properties, Uses, Production

Uses

5H-[1,3]dioxolo[4,5-f]indole (5,6-Methylenedioxyindole) is an indole analogue commonly used in the preparation of other biologically active molecules, such as fungicides and anticancer agents.

Synthesis

Phosphonium, [2-(1,1-dimethylethoxy)-2-oxoethyl]triphenyl-, inner salt

86302-43-4

6-NITROPIPERONAL

712-97-0

5,6-Methylenedioxyindole

267-48-1

The general procedure for the synthesis of 5,6-methylenedioxyindole from [2-(1,1-dimethylethoxy)-2-oxoethyl]triphenylphosphonium inner salt and 6-nitropiperonyl aldehyde was as follows: In a 50 mL round-bottomed flask equipped with a magnetic stirrer, 6-nitropiperonyl aldehyde (2 mmol), [2-(1,1-dimethylethoxy)-2-oxoethyl]triphenylphosphonium inner salt (2.2 mmol), triphenylphosphine (4.6 mmol), and diphenyl ether (10 mL) were added in sequence. mmol), triphenylphosphine (4.6 mmol) and diphenyl ether (10 mL). The reaction mixture was heated to 260 °C and kept for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and the crude product was directly sampled onto a silica gel column. Separation was carried out by column chromatography using a gradient elution system of petroleum ether to 3:1 (v/v) petroleum ether/ethyl acetate to purify the target product 5,6-methylenedioxyindole.

References

[1] Tetrahedron Letters, 2018, vol. 59, # 19, p. 1851 - 1854

5,6-Methylenedioxyindole synthesis

100587-74-4
267-48-1
Synthesis of 5,6-Methylenedioxyindole from 5H-1,3-Dioxolo[4,5-f]indole, 5-(phenylsulfonyl)-

5,6-Methylenedioxyindole Preparation Products And Raw materials

Raw materials

5H-1,3-Dioxolo[4,5-f]indole, 5-(phenylsulfonyl)- 2-(6-bromo-1,3-dioxaindan-5-yl)ethan-1-amine 6-Nitropiperonal Homopiperonylamine Phosphonium, [2-(1,1-dimethylethoxy)-2-oxoethyl]triphenyl-, inner salt
3,4-(Methylenedioxy)aniline Ethylene glycol Triphenylphosphine Diphenyl ether

1of2

Preparation Products

5,6-Methylenedioxyindole Suppliers

Global Suppliers ( 78)
Supplier Tel Email Country ProdList Advantage
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
BTC Pharmaceutical CO. Ltd +86-15716293042 15716293042 info@btcpharm.com China 822 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Shanghai ZiHao Pharmaceutical Co., Ltd. 021-13482410-12 13482410112; 362383684@qq.com China 751 58
Zhengzhou Ruke Biological Co., Ltd. 15981811963 1410472904@qq.com China 5824 58
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6039 18920764717 sales@heowns.com China 24650 60
Supplier Advantage
Shanghai Hanhong Scientific Co.,Ltd. 64
Bide Pharmatech Ltd. 60
Cool Pharm, Ltd 58
BTC Pharmaceutical CO. Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Aikon International Limited 58
Shanghai ZiHao Pharmaceutical Co., Ltd. 58
Zhengzhou Ruke Biological Co., Ltd. 58
Tianjin heowns Biochemical Technology Co., Ltd. 60

View Latest Price from 5,6-Methylenedioxyindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5,6-METHYLENEDIOXYINDOLE pictures 2026-06-30 5,6-METHYLENEDIOXYINDOLE
267-48-1
 1KG 98% 1000KG Shaanxi Dideu New Materials Co. Ltd
5-6-methylenedioxyindole tan crystals pictures 2024-02-26 5-6-methylenedioxyindole tan crystals
267-48-1
 1kg 98% BTC Nantong Pharmaceuticals Technology Co.,Ltd
5,6-METHYLENEDIOXYINDOLE pictures 2020-01-10 5,6-METHYLENEDIOXYINDOLE
267-48-1
 $1.00 1g 99.0% 100kg Career Henan Chemical Co

5,6-Methylenedioxyindole Spectrum

5,6-Methylenedioxyindole(267-48-1)1HNMR

267-48-1 (5,6-Methylenedioxyindole) Related Search:

5,6-Methylenedioxyindole-3-carboxylic acid 5,6-Methylenedioxy-2-phenylindole 2-Ethyl-5,6-methylendioxyindole 4,5-Methylenedioxyindole 5-Benzyl-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid
5H-[1,3]Dioxolo[4,5-f]indole-6-carboxylic acid methyl ester 2-methyl-3-(gamma-aminopropyl)-5,6-methylenedioxyindole 7-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-5H-1,3-dioxolo[4, 5-f]i ndole tartrate Solypertine 1-((1,1-Dimethyl)amino)-3-(5H-1,3-dioxolo(4,5-f)pyrido(3,4-b)indol-9-y loxy)-2-propanol
5,6-METHYLENEDIOXYINDOLE

1of3

5h-1,3-dioxolo(4,5-f)indole 5,6-METHYLENEDIOXYINDOLE 5-6-methylenedioxyindole tan crystals 5H-[1,3]dioxolo[4,5-f]indol 5H-[1,3]Dioxolo[4,5-f]indole - [D71752] 267-48-1 Building Blocks Heterocyclic Building Blocks Indoles Indoles and derivatives Building Blocks Heterocyclic Building Blocks Indoles