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3-[(Benzyloxycarbonyl)amino]propionaldehyde

3-[(Benzyloxycarbonyl)amino]propionaldehyde structure

CAS No.: 65564-05-8

Chemical Name:: 3-[(Benzyloxycarbonyl)amino]propionaldehyde

Synonyms: Z-Beta-Ala-al;N-CBZ-3-AMinopropanal;Benzyl 3-oxopropylcarbaMate;(3-Oxo-propyl)-carbamic acid benzyl ester;3-(Cbz-amino)propanal;N-Cbz-3-oxopropanamine;Benzyl N-(3-oxopropyl)carbamate;3-Aminopropanal, N-CBZ protected;3-(Carbobenzoxyamino)propionaldehyde;3-Aminopropanal, N-CBZ protected 97%

CBNumber:: CB8366386

Molecular Formula:: C11H13NO3

Molecular Weight:: 207.23

MDL Number:: MFCD05664298

MOL File:: 65564-05-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:35:56

Product description	Number	Pack Size	Price
3-[(Benzyloxycarbonyl)amino]propionaldehyde 95%	592951	1g	$116
Benzyl (3-Oxopropyl)carbamate	P3040	1G	$130
BENZYL 3-OXOPROPYLCARBAMATE 95%	53998	1G	$76
BENZYL 3-OXOPROPYLCARBAMATE 95%	53998	5G	$168
BENZYL 3-OXOPROPYLCARBAMATE 95%	53998	25G	$504
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3-[(Benzyloxycarbonyl)amino]propionaldehyde Properties

Melting point	52-57 °C (lit.)
Boiling point	370.1±35.0 °C(Predicted)
Density	1.142±0.06 g/cm3(Predicted)
storage temp.	2-8°C
form	Crystalline Powder
pka	12.08±0.46(Predicted)
color	White to yellow
InChI	InChI=1S/C11H13NO3/c13-8-4-7-12-11(14)15-9-10-5-2-1-3-6-10/h1-3,5-6,8H,4,7,9H2,(H,12,14)
InChIKey	PQMOZOQTXKMYSK-UHFFFAOYSA-N
SMILES	C(OCC1=CC=CC=C1)(=O)NCCC=O
CAS DataBase Reference	65564-05-8(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Hazard Codes	Xi
WGK Germany	3
HS Code	29223900
Storage Class	11 - Combustible Solids

3-[(Benzyloxycarbonyl)amino]propionaldehyde price More Price(57)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	592951	3-[(Benzyloxycarbonyl)amino]propionaldehyde 95%	65564-05-8	1g	$116	2026-04-30	Buy
TCI Chemical	P3040	Benzyl (3-Oxopropyl)carbamate	65564-05-8	1G	$130	2026-04-30	Buy
AstaTech	53998	BENZYL 3-OXOPROPYLCARBAMATE 95%	65564-05-8	1G	$76	2026-04-30	Buy
AstaTech	53998	BENZYL 3-OXOPROPYLCARBAMATE 95%	65564-05-8	5G	$168	2026-04-30	Buy
AstaTech	53998	BENZYL 3-OXOPROPYLCARBAMATE 95%	65564-05-8	25G	$504	2026-04-30	Buy

Product number	Packaging	Price	Buy
592951	1g	$116	Buy
P3040	1G	$130	Buy
53998	1G	$76	Buy
53998	5G	$168	Buy
53998	25G	$504	Buy

3-[(Benzyloxycarbonyl)amino]propionaldehyde Chemical Properties,Uses,Production

Chemical Properties

White to yellow crystalline powder

Uses

3-(Benzyloxycarbonylamino)propionaldehyde is used as a reagent in the synthesis of Tuberactinomycin N, a peptide antibiotic that is used as an anti-tuberculotic drug. 3-(Benzyloxycarbonylamino)propionaldehyde is also used as a reagent to prepare L-epicapreomycidine, a guanidino amino acid that is naturally found in hydrolyzates of protease inhibitors.

Synthesis

34637-22-4

3-[(Benzyloxycarbonyl)amino]propionaldehyde

65564-05-8

The general procedure for the synthesis of N-benzyloxycarbonyl-3-aminopropanal from 3-(benzyloxycarbonylamino)-1-propanol was as follows: PCC (8.75 g, 40.6 mmol, 1.7 eq.) and Celite (9 g) were stirred in dichloromethane (50 mL) for 5 min, followed by the addition of 3-(benzyloxycarbonylamino)-1-propanol (5.0 g, 24 mmol) dissolved in dichloromethane (30 mL). propanol (5.0 g, 24 mmol). After 4 hours of reaction, the reaction mixture was diluted with ether (100 mL) and filtered through a short pad of silica gel and Celitefilter. The residual solid was suspended in dichloromethane (25 mL) and precipitated with ether (50 mL) to pass the mixture through the same filter pad. After this process was repeated three times, the filtrate was evaporated under reduced pressure to give a yellow oil (5.0 g). Purification by column chromatography (petroleum ether solution of 40% ethyl acetate) afforded N-benzyloxycarbonyl-3-aminopropionaldehyde as a colorless viscous oil (3.0 g, 14.5 mmol) in 60% yield. rf value of 0.4 (petroleum ether solution of 50% ethyl acetate, PMA color developed); 1H NMR (CDCl3) δ: 2.75 (2H, t, J=5.7Hz. CH2), 3.49 (2H, apparent q, J=6.0 Hz, CH2), 5.09 (2H, s, CH2), 5.15 (1H, br s, NH), 7.30-7.39 (5H, m, Ar), 9.81 (1H, s, CHO); 13C NMR (CDCl3) δ: 34.6, 44.2, 66.9, 128.2 , 128.3, 128.7, 136.5, 165.4, 201.3; IR (neat) νmax: 3445, 1704, 1645 cm-1.

References

[1] Tetrahedron Letters, 2001, vol. 42, # 2, p. 183 - 185
[2] European Journal of Organic Chemistry, 2012, # 17, p. 3270 - 3277
[3] Tetrahedron, 1997, vol. 53, # 37, p. 12391 - 12404
[4] Tetrahedron Letters, 1987, vol. 28, # 33, p. 3827 - 3830
[5] Synlett, 2017, vol. 28, # 13, p. 1554 - 1557

3-[(Benzyloxycarbonyl)amino]propionaldehyde Preparation Products And Raw materials

Raw materials

Hydrazinium hydroxide solution N-Aminoethylpiperazine 3-Chloropropionaldehyde diethylacetal Dichloromethane Benzyl chloroformate

Potassium phthalimide BENZYL N-(3-HYDROXYPROPYL)CARBAMATE Pyridinium chlorochromate

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Preparation Products

BENZYL N-(3-HYDROXYPROPYL)CARBAMATE

3-[(Benzyloxycarbonyl)amino]propionaldehyde Suppliers

Global( 144)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569262 +86-15003564040	1056@dideu.com	China	3970	58
Fuxin Pharmaceutical	+86-021-021-50872116	contact@fuxinpharm.com	China	9976	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9666	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
Hefei Hangang Pharmaceutical Technology Co., Ltd.	+8618062405514	ada@ipurechemical.com	China	10224	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9036	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Fuxin Pharmaceutical	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58
Hefei Hangang Pharmaceutical Technology Co., Ltd.	58
Baoji Guokang Healthchem Co., Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from 3-[(Benzyloxycarbonyl)amino]propionaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-02	3-[(Benzyloxycarbonyl)amino]propionaldehyde 65564-05-8		10mg	99%HPLC	2000tons	Shaanxi Dideu Medichem Co. Ltd
2021-07-13	3-[(Benzyloxycarbonyl)amino]propionaldehyde 65564-05-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10	3-[(Benzyloxycarbonyl)amino]propionaldehyde 65564-05-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

3-[(Benzyloxycarbonyl)amino]propionaldehyde
65564-05-8
99%HPLC
Shaanxi Dideu Medichem Co. Ltd

3-[(Benzyloxycarbonyl)amino]propionaldehyde
65564-05-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

3-[(Benzyloxycarbonyl)amino]propionaldehyde
65564-05-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

3-[(Benzyloxycarbonyl)amino]propionaldehyde Spectrum

3-[(Benzyloxycarbonyl)amino]propionaldehyde(65564-05-8)¹HNMR

65564-05-8(3-[(Benzyloxycarbonyl)amino]propionaldehyde)Related Search:

Trimethoprim N-Carbobenzyloxyglycine Propionaldehyde Phenylpropyl aldehyde Tris(hydroxymethyl)aminomethane

Glycine Aminoethoxyvinyl glycine hydrochloride Carbobenzyloxy-beta-alanine CBZ-ASP(OBZL)-OBZL N-Benzyloxycarbonyl-L-asparagine

N-CARBOBENZOXY-DL-ASPARTIC ACID N-Cbz-L-Aspartic acid 4-benzyl ester 2-Aminobenzylchloride N-Carbobenzyloxy-L-aspartic acid Z-ASP(OTBU)-OH DCHA

Z-ASN-ONP Z-ASP-OBZL N-Cbz-L-Aspartic acid 4-tert-butyl ester

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3-[(Benzyloxycarbonyl)aMino]propionaldehyde 95% (3-Oxo-propyl)-carbamic acid benzyl ester 3-[(BENZYLOXYCARBONYL)AMINO]PROPIONALDEHYDE 3-[(BENZYLOXYCARBONYL)AMINO]-1-PROPANAL 3-[(Carbobenzyloxy)amino]propionaldehyde Benzyl N-(3-oxopropyl)carbamate N-Phenylmethoxycarbonyl-3-aminopropanol N-Phenylmethoxycarbonyl-3-Aminopropanal 3-Aminopropanal, N-CBZ protected 97% N-(3-oxopropyl)carbamic acid (phenylmethyl) ester 3-[(Benzyloxycarbonyl)amino]-1-propanal ,95% 3-[(Benzyloxycarbonyl)amino]propionaldehyde,3-[(Benzyloxycarbonyl)amino]-1-propanal, 3-[(Carbobenzyloxy)amino]propionaldehyde 3-((BENZYLOXYCARBONYL)AMINO)-1-PROPANOL& 3-[(Benzyloxycarbonyl)amino]propionaldehyde, Benzyl (3-oxopropyl)carbamate 3-Aminopropanal, N-CBZ protected 3-[(Benzyloxycarbonyl)amino]-1-propanal, 3-[(Carbobenzyloxy)amino]propionaldehyde 3-Hydroxypropyl(benzyloxycarbonyl)amine 3-Hydroxypropylcarbamic acid benzyl ester 3-[(Benzyloxycarbonyl)amino]propionaldehyde,95% N-CBZ-3-AMinopropanal Benzyl 3-oxopropylcarbaMate Carbamic acid, N-(3-oxopropyl)-, phenylmethyl ester Z-Beta-Ala-al 3-(Cbz-amino)propanal N-Cbz-3-oxopropanamine Phenylmethyl N-(3-oxopropyl)carbamate 3-(Carbobenzoxyamino)propionaldehyde 65564-05-8 C6H5CH2O2CNHCH2CH2CHO Organic Building Blocks Building Blocks Aldehydes Carbonyl Compounds C10 to C21