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4-Methoxypyridine

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Company Name: Henan Fengda Chemical Co., Ltd
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Products Intro: Product Name:4-Methoxypyridine
CAS:620-08-6
Purity:98% Package:1KG;6USD|1000KG;0.2USD
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CAS:620-08-6
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CAS:620-08-6
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Company Name: Shanghai Daken Advanced Materials Co.,Ltd
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CAS:620-08-6
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Products Intro: Product Name:4-Methoxypyridine
CAS:620-08-6

4-Methoxypyridine manufacturers

  • 4-Methoxypyridine
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  • $0.00 / 25KG
  • 2025-12-01
  • CAS:620-08-6
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 10000KGS
  • 4-Methoxypyridine
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  • 2025-11-18
  • CAS:620-08-6
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  • Purity: 99.00%
  • Supply Ability: 100 Tons Min
  • 4-Methoxypyridine
  • 4-Methoxypyridine pictures
  • $6.00 / 1KG
  • 2025-09-25
  • CAS:620-08-6
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: g-kg-tons, free sample is available
4-Methoxypyridine Basic information
Product Name:4-Methoxypyridine
Synonyms:gamma-Methoxypyridine;4-METHOXYPYRIDINE;METHYL PYRIDIN-4-YL ETHER;4-METHOXYPYRIDINE, 98+%;4-methoxypridine;Pyridine, 4-methoxy-;4-Methoxypyridine, 99% 5ML;4-Methoxypyridine,99%
CAS:620-08-6
MF:C6H7NO
MW:109.13
EINECS:210-624-7
Product Categories:Heterocyclic Building Blocks;Pyridines, Pyrimidines, Purines and Pteredines;Boronic Acid;Pyridine Derivertives;Pyridine series;blocks;Pyridines;Pyridine;C6
Mol File:620-08-6.mol
4-Methoxypyridine Structure
4-Methoxypyridine Chemical Properties
Melting point 4 °C
Boiling point 108-111 °C/65 mmHg (lit.)
density 1.075 g/mL at 25 °C (lit.)
refractive index 1.518-1.522
Fp 74 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka6.58(at 25℃)
form Liquid
color Clear colorless to slightly yellow
Specific Gravity1.075
BRN 108211
InChIInChI=1S/C6H7NO/c1-8-6-2-4-7-5-3-6/h2-5H,1H3
InChIKeyXQABVLBGNWBWIV-UHFFFAOYSA-N
SMILESC1=NC=CC(OC)=C1
CAS DataBase Reference620-08-6(CAS DataBase Reference)
NIST Chemistry ReferencePyridine, 4-methoxy-(620-08-6)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-20/21/22
Safety Statements 37/39-26-36-36/37/39
WGK Germany 3
HS Code 29339900
Storage Class10 - Combustible liquids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
ACROS English
ALFA English
4-Methoxypyridine Usage And Synthesis
Chemical Propertiesclear colorless to slightly yellow liquid
Uses4-Methoxypyridine, is used as a building block for the synthesis of some biologically active compounds. It is used for the preparation of a new series of benzoylated N-ylides as protein farnesyltransferase inhibitors.
Uses4-Methoxypyridine was used as a starting reagent for the stereocontrolled synthesis of (±)-pumiliotoxin C and (±)-lasubine II. It was also used in an efficient construction of dihyropyridin-4-ones, which serves as potential ligands for neuronal nicotinic acetycholine receptors.
General Description4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied.
Synthesis

At room temperature, (50mmo1) 4-methoxypyridine-N-oxide was dissolved in 50mL acetonitrile solution, then 1.01g (55mmo1) tritiated cyanogen chloride (TCT) was added to the reaction solution in batches, and the reaction was tracked by TCL, and at the end of the reaction, 20mL of saturated sodium carbonate solution was added dropwise to the reaction solution, and the reaction was stirred for 30min. dichloromethane was added to extract, and the organic phase was respectively The organic phase was washed with water and saturated saline, and the crude product was obtained by spinning off the solvent under reduced pressure. The crude product was purified by column to get the target product. Light yellow oily liquid.

 

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