- 4-Methoxypyridine
-
- $0.00 / 25KG
-
2025-12-01
- CAS:620-08-6
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 10000KGS
- 4-Methoxypyridine
-
- $1.10 / 1g
-
2025-11-18
- CAS:620-08-6
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons Min
- 4-Methoxypyridine
-
- $6.00 / 1KG
-
2025-09-25
- CAS:620-08-6
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: g-kg-tons, free sample is available
|
| | 4-Methoxypyridine Basic information |
| | 4-Methoxypyridine Chemical Properties |
| Melting point | 4 °C | | Boiling point | 108-111 °C/65 mmHg (lit.) | | density | 1.075 g/mL at 25 °C (lit.) | | refractive index | 1.518-1.522 | | Fp | 74 °C | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 6.58(at 25℃) | | form | Liquid | | color | Clear colorless to slightly yellow | | Specific Gravity | 1.075 | | BRN | 108211 | | InChI | InChI=1S/C6H7NO/c1-8-6-2-4-7-5-3-6/h2-5H,1H3 | | InChIKey | XQABVLBGNWBWIV-UHFFFAOYSA-N | | SMILES | C1=NC=CC(OC)=C1 | | CAS DataBase Reference | 620-08-6(CAS DataBase Reference) | | NIST Chemistry Reference | Pyridine, 4-methoxy-(620-08-6) |
| Hazard Codes | Xn,Xi | | Risk Statements | 36/37/38-20/21/22 | | Safety Statements | 37/39-26-36-36/37/39 | | WGK Germany | 3 | | HS Code | 29339900 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| | 4-Methoxypyridine Usage And Synthesis |
| Chemical Properties | clear colorless to slightly yellow liquid | | Uses | 4-Methoxypyridine, is used as a building block for the synthesis of some biologically active compounds. It is used for the preparation of a new series of benzoylated N-ylides as protein farnesyltransferase inhibitors. | | Uses | 4-Methoxypyridine was used as a starting reagent for the stereocontrolled synthesis of (±)-pumiliotoxin C and (±)-lasubine II. It was also used in an efficient construction of dihyropyridin-4-ones, which serves as potential ligands for neuronal nicotinic acetycholine receptors. | | General Description | 4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied. | | Synthesis | At room temperature, (50mmo1) 4-methoxypyridine-N-oxide was dissolved in 50mL acetonitrile solution, then 1.01g (55mmo1) tritiated cyanogen chloride (TCT) was added to the reaction solution in batches, and the reaction was tracked by TCL, and at the end of the reaction, 20mL of saturated sodium carbonate solution was added dropwise to the reaction solution, and the reaction was stirred for 30min. dichloromethane was added to extract, and the organic phase was respectively The organic phase was washed with water and saturated saline, and the crude product was obtained by spinning off the solvent under reduced pressure. The crude product was purified by column to get the target product. Light yellow oily liquid.
|
| | 4-Methoxypyridine Preparation Products And Raw materials |
|