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(5-Amino-1H-1,2,4-triazol-3-yl)methanol

CAS No.
63870-39-3
Chemical Name:
(5-Amino-1H-1,2,4-triazol-3-yl)methanol
Synonyms
NSC513582;ZERO/004602;ZINC02415220;ASINEX-REAG BAS 03825303;(3-Amino-1H-1,2,4-triazol-5-yl);(5-amino-2H-1,2,4-triazol-3-yl)methanol;(5-Amino-1H-1,2,4-triazol-3-yl)methanol;methanol compound with 2-hydroxyacetic acid;(3-AMINO-1H-1,2,4-TRIAZOL-5-YL)METHANOL 2-HYDROXYACETIC ACID;(3-AMino-1H-1,2,4-triazol-5-yl)Methanol coMpound with 2-hydroxyacetic acid
CBNumber:
CB8406064
Molecular Formula:
C3H6N4O
Molecular Weight:
114.11
MDL Number:
MFCD02933180
MOL File:
63870-39-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:43

(5-Amino-1H-1,2,4-triazol-3-yl)methanol Properties

Melting point 114-115 °C(Solv: ethanol (64-17-5))
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
EPA Substance Registry System Acetic acid, hydroxy-, compd. with 5-amino-1H-1,2,4-triazole-3-methanol (1:1) (63870-39-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
TSCA  TSCA listed

(5-Amino-1H-1,2,4-triazol-3-yl)methanol price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00EATJ (3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid 63870-39-3 250mg $610 2026-05-28 Buy
aablocks AA00EATJ (3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid 63870-39-3 500mg $741 2026-05-28 Buy
aablocks AA00EATJ (3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid 63870-39-3 1g $937 2026-05-28 Buy
aablocks AA00EATJ (3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid 63870-39-3 2g $1508 2026-05-28 Buy
Crysdot CD11082274 (3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid 95+% 63870-39-3 100mg $65 2026-05-26 Buy
Product number Packaging Price Buy
AA00EATJ 250mg $610 Buy
AA00EATJ 500mg $741 Buy
AA00EATJ 1g $937 Buy
AA00EATJ 2g $1508 Buy
CD11082274 100mg $65 Buy

(5-Amino-1H-1,2,4-triazol-3-yl)methanol Chemical Properties, Uses, Production

Synthesis

Glycolic acid

79-14-1

Aminoguanidine bicarbonate

2582-30-1

(5-AMINO-1H-1,2,4-TRIAZOL-3-YL)METHANOL

63870-39-3

Aminoguanidine bicarbonate (23.5 g, 172 mmol) was added in batches to a mixture of ethanoic acid (26.2 g, 345 mmol) and water (10 mL) over a period of 0.1 hours. During the addition, the reaction mixture was gently heated to maintain the internal temperature at 25 °C. Subsequently, concentrated nitric acid (1.0 mL) was added slowly and dropwise to the reaction system, and then the reaction mixture was heated to an internal temperature of 104-108 °C over 22 hours. Upon completion of the reaction, the heating was stopped and the solution was allowed to cool naturally with stirring. The slurry cooled to 10 °C was continued to be stirred for 2 h. Subsequently, it was filtered and the filter cake was washed with ethanol (EtOH). The resulting solid was dried overnight under vacuum to afford the target product (5-amino-1H-1,2,4-triazol-3-yl) methanol ethanolate (Product 88a, 29.5 g, 85% yield). Mass spectrometry analysis: calculated value (M + H)+ = 115, measured value (M + H)+ = 115.

References

[1] Patent: WO2012/83105, 2012, A1. Location in patent: Page/Page column 101
[2] Patent: WO2007/23381, 2007, A1. Location in patent: Page/Page column 54-55
[3] Patent: WO2004/74270, 2004, A2. Location in patent: Page 300
[4] Patent: US2005/176701, 2005, A1. Location in patent: Page/Page column 144

(5-Amino-1H-1,2,4-triazol-3-yl)methanol Preparation Products And Raw materials

Raw materials

Preparation Products

(5-Amino-1H-1,2,4-triazol-3-yl)methanol Suppliers

Global Suppliers ( 30)
Supplier Tel Email Country ProdList Advantage
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
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Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
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Shanghai Sunway Pharmaceutical Technology Co.,Ltd. 13611835272 13611835272 mmwang@sunwaypharm.com China 44090 58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd 2383948258 19172820304 2383948258@qq.com China 12983 58
Beijing Stronger Science Co., Ltd. 0531-88924771 15614660963 elsa.hang@strongerscience.com China 10622 58
ASINEX-REAG BAS 03825303 (3-AMino-1H-1,2,4-triazol-5-yl)Methanol coMpound with 2-hydroxyacetic acid (5-amino-2H-1,2,4-triazol-3-yl)methanol Acetic acid, hydroxy-, compd. with 5-amino-1H-1,2,4-triazole-3-methanol (1:1) NSC513582 ZERO/004602 ZINC02415220 (3-Amino-1H-1,2,4-triazol-5-yl) methanol compound with 2-hydroxyacetic acid (3-AMINO-1H-1,2,4-TRIAZOL-5-YL)METHANOL 2-HYDROXYACETIC ACID (5-Amino-1H-1,2,4-triazol-3-yl)methanol 63870-39-3 C3H6N4OC2H4O3