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ChemicalBook >> CAS DataBase List >>2-(4-Chlorophenyl)thiazole-5-carbaldehyde

2-(4-Chlorophenyl)thiazole-5-carbaldehyde

2-(4-Chlorophenyl)thiazole-5-carbaldehyde Structure
2-(4-Chlorophenyl)thiazole-5-carbaldehyde structure
CAS No.
721920-84-9
Chemical Name:
2-(4-Chlorophenyl)thiazole-5-carbaldehyde
Synonyms
2-(4-CHLOROPHENYL)THIAZOLE-5-CARBALDEHYDE;2-(4-hydroxyphenyl)thiazole-5-carbaldehyde;5-Thiazolecarboxaldehyde, 2-(4-chlorophenyl)-;2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde
CBNumber:
CB8406903
Molecular Formula:
C10H6ClNOS
Molecular Weight:
223.68
MDL Number:
MFCD05864657
MOL File:
721920-84-9.mol
MSDS File:
SDS
Last updated:2026-05-28 05:00:09
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2-(4-Chlorophenyl)thiazole-5-carbaldehyde Properties

Boiling point 377.6±48.0 °C(Predicted)
Density 1.388±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 0.14±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  43
Safety Statements  36/37

2-(4-Chlorophenyl)thiazole-5-carbaldehyde price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 071667 2-(4-Chlorophenyl)thiazole-5-carbaldehyde 721920-84-9 250.00mg $107 2026-05-18 Buy
Matrix Scientific 071667 2-(4-Chlorophenyl)thiazole-5-carbaldehyde 721920-84-9 1.00g $166 2026-05-18 Buy
Matrix Scientific 071667 2-(4-Chlorophenyl)thiazole-5-carbaldehyde 721920-84-9 5.00g $490 2026-05-18 Buy
Ambeed A180832 2-(4-Chlorophenyl)thiazole-5-carbaldehyde 95% 721920-84-9 250mg $80 2026-06-05 Buy
Ambeed A180832 2-(4-Chlorophenyl)thiazole-5-carbaldehyde 95% 721920-84-9 1g $130 2026-06-05 Buy
Product number Packaging Price Buy
071667 250.00mg $107 Buy
071667 1.00g $166 Buy
071667 5.00g $490 Buy
A180832 250mg $80 Buy
A180832 1g $130 Buy

2-(4-Chlorophenyl)thiazole-5-carbaldehyde Chemical Properties, Uses, Production

Synthesis

2-CHLOROMALONALDEHYDE

36437-19-1

4-Chlorothiobenzamide

2521-24-6

2-(4-Chlorophenyl)thiazole-5-carbaldehyde

721920-84-9

Step 1. Synthesis of 2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde. 4-Chlorobenzamide (5 g, 29.1 mmol), magnesium bicarbonate pentahydrate (7.06 g, 14.55 mmol) and 2-chloromalonaldehyde (4.65 g, 43.65 mmol) were added to a flask and the reaction was stirred for 3 hr at 60 °C under nitrogen protection. Upon completion of the reaction, the reaction mixture was allowed to pass through a silica plug for rapid column chromatography and washed with ethyl acetate. The solvent was removed by concentration under reduced pressure to afford the target product 2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde (6 g, 92% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 10.06 (s, 1H), 8.43 (s, 1H), 7.99-7.96 (m, 2H), 7.49-7.46 (m, 2H).

References

[1] Patent: WO2004/58761, 2004, A1. Location in patent: Page 37-38
[2] Patent: WO2011/12862, 2011, A1. Location in patent: Page/Page column 102; 109

2-(4-Chlorophenyl)thiazole-5-carbaldehyde Preparation Products And Raw materials

Raw materials

2-Chloromalonaldehyde 4-Chlorothiobenzamide tetra[carbonato(2-)]dihydroxypentamagnesium

Preparation Products

2-(4-Chlorophenyl)thiazole-5-carbaldehyde Suppliers

Global Suppliers ( 52)
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Scientia Pharmaceutical Technology Co., Ltd. 21-21-54301573 13917723525 sales@scientiapharm.com China 260 62
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
Moltt Biocem Co., Ltd. +86-21-38682181 15900741819 China 281 55
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189;18621755571 mychess007@163.com China 1994 55
Hubei Jusheng Technology Co.,Ltd 027-59599241 18871490274 1400878000@qq.com China 9506 58
JW & Y Pharmlab Co., Ltd. 021-64340559 xinyu_shi@jwypharmlab.com.cn China 11999 58
Yancheng Schiemann Biological Technology Co.,Ltd 0515-88280676; 18921872653 sales@ximanbio.com China 1524 56
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
Capot Chemical Co., Ltd 66
Shanghai Scientia Pharmaceutical Technology Co., Ltd. 62
Pure Chemistry Scientific Inc. 62
Shanghai Ennopharm Co., Ltd. 65
Moltt Biocem Co., Ltd. 55
ShangHai KenEn Chemical Technology Co., Ltd. 55
Hubei Jusheng Technology Co.,Ltd 58
JW & Y Pharmlab Co., Ltd. 58
Yancheng Schiemann Biological Technology Co.,Ltd 56
Amadis Chemical Company Limited 58

View Latest Price from 2-(4-Chlorophenyl)thiazole-5-carbaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(4-Chlorophenyl)thiazole-5-carbaldehyde pictures 2020-01-03 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
721920-84-9
 $1.00 1KG 95-99% 1ton Career Henan Chemical Co

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2-(4-CHLOROPHENYL)THIAZOLE-5-CARBALDEHYDE 2-(4-hydroxyphenyl)thiazole-5-carbaldehyde 2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde 5-Thiazolecarboxaldehyde, 2-(4-chlorophenyl)- 721920-84-9 C10H6ClNOS API intermediates