HS-1793
- CAS No.
- 927885-00-5
- Chemical Name:
- HS-1793
- Synonyms
- HS-1793;HS-1793, 10 mM in DMSO;1,3-Benzenediol, 4-(6-hydroxy-2-naphthalenyl)-;HIF-1α,Inhibitor,MCF-7,HS 1793,breast cancer,inhibit,ERK,HCT116,resveratrol,VEGF,Apoptosis,HS-1793,Akt,colon cancer,HS1793
- CBNumber:
- CB84198169
- Molecular Formula:
- C16H12O3
- Molecular Weight:
- 252.26
- MDL Number:
- MFCD30719244
- MOL File:
- 927885-00-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| HS-1793 99.26% | CS-0103797 | 5mg | $97 |
| HS-1793 99.26% | CS-0103797 | 10mg | $162 |
| HS-1793 | BA3100 | 5mg | $81 |
| HS-1793 | BA3100 | 10mg | $135 |
| HS-1793 | BA3100 | 25mg | $222 |
| Melting point | 186 °C |
|---|---|
| Boiling point | 520.8±19.0 °C(Predicted) |
| Density | 1.370±0.06 g/cm3(Predicted) |
| pka | 9.31±0.35(Predicted) |
| form | Solid |
| color | Off-white to light yellow |
| InChI | InChI=1S/C16H12O3/c17-13-4-3-10-7-12(2-1-11(10)8-13)15-6-5-14(18)9-16(15)19/h1-9,17-19H |
| InChIKey | BXZJBSHLEZAMOP-UHFFFAOYSA-N |
| SMILES | C1(O)=CC=C(C2=CC=C3C(=C2)C=CC(O)=C3)C(O)=C1 |
| FDA UNII | 5YWK2UV4R5 |
HS-1793 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0103797 | HS-1793 99.26% | 927885-00-5 | 5mg | $97 | 2026-06-04 | Buy |
| ChemScene | CS-0103797 | HS-1793 99.26% | 927885-00-5 | 10mg | $162 | 2026-06-04 | Buy |
| ApexBio Technology | BA3100 | HS-1793 | 927885-00-5 | 5mg | $81 | 2026-05-06 | Buy |
| ApexBio Technology | BA3100 | HS-1793 | 927885-00-5 | 10mg | $135 | 2026-05-06 | Buy |
| ApexBio Technology | BA3100 | HS-1793 | 927885-00-5 | 25mg | $222 | 2026-05-06 | Buy |
HS-1793 Chemical Properties,Uses,Production
Uses
HS-1793 is a Resveratrol (HY-16561) analogue with antitumor activities in a variety of cancer cell lines[1]. HS-1793 induces cell apoptosis[2].
in vivo
HS-1793 (5 and 10 mg/kg; i.p.; twice a week, 4 weeks) significantly inhibits MDA-MB-231 xenograft tumor growth and in a dose-dependent manner and relatively hampers angiogenesis with non-toxicity[1].
| Animal Model: | Five-week-old female BALB/c nude mice injected with MDA-MB-231 cells[1] |
| Dosage: | 5 mg/kg and 10 mg/kg (dissolved in PBS containing 0.1% v/v dimethyl sulfoxide (DMSO)) |
| Administration: | Intraperitoneal injection, twice a week, 4 weeks |
| Result: | Significantly inhibited MDA-MB-231 xenograft tumor growth in a dose-dependent manner with non-toxicity. Significantly lowered Ki-67 (a proliferation marker) and CD31 expression. Successfully suppressed the expression of HIF-1α and VEGF in tumor tissues. |
References
[1] Kim DH, et al. HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model. Int J Oncol. 2017 Aug;51(2):715-723. DOI:10.3892/ijo.2017.4058
[2] Kim DH, et al. Resveratrol analogue, HS-1793, induces apoptotic cell death and cell cycle arrest through downregulation of AKT in human colon cancer cells. Oncol Rep. 2017 Jan;37(1):281-288. DOI:10.3892/or.2016.5219
HS-1793 Preparation Products And Raw materials
Raw materials
Preparation Products
HS-1793 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4857 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9807 | 58 |
