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2,2'-Methylenebis(4-methyl-6-tert-butylphenol)

CAS No.
119-47-1
Chemical Name:
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)
Synonyms
2246;ao2246;BKF;Methylenebisbutylcresol;METHYLENE DI-t-BUTYLCRESOL;ao1;Cyanox 2246;Bisalkofen BP;antiox;Ralox 46
CBNumber:
CB8468783
Molecular Formula:
C23H32O2
Molecular Weight:
340.5
MDL Number:
MFCD00043641
MOL File:
119-47-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-31 17:49:05

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) Properties

Melting point 123-127 °C(lit.)
Boiling point 187℃
Density 1.04g/cm3
bulk density 300kg/m3
vapor pressure <1 hPa
refractive index 1.4480 (estimate)
Flash point 195°C(383°F)
storage temp. Store below +30°C.
solubility 0.007mg/l practically insoluble
form White to off-white solid.
pka 11.32±0.48(Predicted)
color White to Off-White
PH 4-7 (H2O, 20℃)(aqueous suspension)
Water Solubility 7μg/L at 20℃
Henry's Law Constant 1.2×106 mol/(m3Pa) at 25℃, HSDB (2015)
Cosmetics Ingredients Functions ANTIOXIDANT
InChI 1S/C23H32O2/c1-14-9-16(20(24)18(11-14)22(3,4)5)13-17-10-15(2)12-19(21(17)25)23(6,7)8/h9-12,24-25H,13H2,1-8H3
InChIKey KGRVJHAUYBGFFP-UHFFFAOYSA-N
SMILES Cc1cc(Cc2cc(C)cc(c2O)C(C)(C)C)c(O)c(c1)C(C)(C)C
LogP 6.25 at 20℃
Substances of Very High Concern (SVHC) Candidate List 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol (119-47-1)
FDA 21 CFR 175.105; 177.2470; 177.2480;177.2600; 178.2010
Indirect Additives used in Food Contact Substances 2,2'-METHYLENEBIS(4-METHYL-6-TERT-BUTYLPHENOL)
CAS DataBase Reference 119-47-1(CAS DataBase Reference)
EWG's Food Scores 1-4
FDA UNII KVM0X4X57B
NIST Chemistry Reference Phenol, 2,2'-methylenebis[6-(1,1-dimethylethyl)-4-methyl-(119-47-1)
EPA Substance Registry System 2,2'-Methylenebis(6-tert-butyl-p-cresol) (119-47-1)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Warning
Hazard statements  H361f-H413
Precautionary statements  P201-P273-P308+P313
Hazard Codes  Xi,Xn
Risk Statements  36-62-53
Safety Statements  26-36-60-36/37
WGK Germany  1
RTECS  PA3500000
Autoignition Temperature 350 °C
TSCA  TSCA listed
HS Code  29072900
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Repr. 1B
Hazardous Substances Data 119-47-1(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 4880 mg/kg LD50 dermal Rabbit > 2000 mg/kg
REACH Registrations Active
NFPA 704
1
2 0

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 413135 2,2′-Methylenebis(6-tert-butyl-4-methylphenol) 119-47-1 100g $73.8 2026-04-30 Buy
Sigma-Aldrich 89968 2,2′-Methylenebis(6-tert-butyl-4-methylphenol) analytical standard 119-47-1 100MG $94.8 2026-04-30 Buy
Sigma-Aldrich 413135 2,2′-Methylenebis(6-tert-butyl-4-methylphenol) 119-47-1 500g $184 2026-04-30 Buy
TCI Chemical M0217 2,2'-Methylenebis(6-tert-butyl-p-cresol) >99.0%(GC) 119-47-1 25g $17 2026-04-30 Buy
TCI Chemical M0217 2,2'-Methylenebis(6-tert-butyl-p-cresol) >99.0%(GC) 119-47-1 250g $42 2026-04-30 Buy
Product number Packaging Price Buy
413135 100g $73.8 Buy
89968 100MG $94.8 Buy
413135 500g $184 Buy
M0217 25g $17 Buy
M0217 250g $42 Buy

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) Chemical Properties, Uses, Production

Chemical Properties

Pure product is white powder, slightly yellowish pink color when exposed to air for a long time. Slightly phenolic odor. Easily soluble in benzene, acetone and other organic solvents, insoluble in water, solubility in rubber is higher than 2%.

Uses

LOWINOX® 22M46 stabilizer is a non-discoloring antioxidant based on a sterically hindered alkylated bis-phenol.

Uses

It may be incorporated into the bromobutyl rubber(BIIR) matrix to enhance the overall thermo-reversibility of dicyclopentadiene dicarboxylic acid (DCPDCA) cross-linked BIIR. It may also be used as an antioxidant which shows a higher oxidation stability in distilled biodiesel.

Definition

ChEBI: 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) is a diarylmethane.

General Description

2,2′-Methylenebis(6-tert-butyl-4-methylphenol) is a phenolic antioxidant commonly used in increasing the oxidation stability in rubber and plastic industries.

Flammability and Explosibility

Not classified

Industrial uses

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) is used in the following products: adhesives and sealants, lubricants and greases, fuels, hydraulic fluids and metal working fluids.

Source

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) is a natural product found in Streptomyces and Aspergillus fumigatus with data available.

Properties and Applications

TEST ITEMS

SPECIFICATION

APPEARANCE

COLORLESS CRYSTALLINE POWDER

CONTENT

98.0% min

MELTING POINT

124 °C +

MELTING RANGE

120-130 °C

VOLATILE

0.3% max

ASH

0.1% max

150um SIEVE RESIDUE

0.5% max

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 460)
Supplier Tel Email Country ProdList Advantage
Powerful Chemical (Shanghai) Co., Ltd. 021-62211590 18917958225; pwfchem@163.com China 75 58
Fuyang Ruidan New Material Technology Co., Ltd. 13861916552 18112233091 sales@fyrdxcl.com China 20 58
Tianjin Zhongxin Chemtech Co., Ltd. 022-66880623 sales@tjzxchem.com China 612 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Nanjing Datang Chemical Co., Ltd 025-85431992 13951889900 vip@chemdatang.com China 100 66

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View Latest Price from 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2'-Methylenebis(6-tert-butyl-4-methylphenol) pictures 2026-09-16 2,2'-Methylenebis(6-tert-butyl-4-methylphenol)
119-47-1
0.99 RongNa Biotechnology Co.,Ltd
2,2'-Methylenebis(6-tert-butyl-4-methylphenol) pictures 2026-09-16 2,2'-Methylenebis(6-tert-butyl-4-methylphenol)
119-47-1
1kg/Bag ≥98% 50 T/Month Hebei Qujie Technology Co., Ltd.
2,2'-Methylenebis(4-methyl-6-tert-butylphenol) pictures 2026-09-16 2,2'-Methylenebis(4-methyl-6-tert-butylphenol)
119-47-1
1kg 98% 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
2,2’-bis 2,2’-bis(6-t-butyl-p-cresyl)-methan LABOTEST-BB LT00159284 IONOL(R) 46 AURORA KA-487 BIS-(3-TERT-BUTYL-2-HYDROXY-5-METHYLPHENYL)-METHAN BIS(3-TERT-BUTYL-2-HYDROXY-5-METHYLPHENYL)METHANE BIS(2-HYDROXY-3-TERT-BUTYL-5-METHYLPHENYL)METHANE 4-Methyl-6-Tertiary Butyl Phenol Thanox2246 22METHYLENEBIS4TERTMETHYL6TERTBUTYLPHENOL 6,6′-Di-tert.-butyl-2,2′-methylendi-p-kresol PHENOL,2,2'-METHYLENEBIS[6-(1) 2,2''-METHYLENEBIS(6-TERT-BUTYL-4-METHYLPHENOL) ---CREAM POWDER--- ANITOXIDANT 2246 At 2246 2-tert-butyl-6-(3-tert-butyl-2-hydroxy-5-methyl-benzyl)-4-methyl-phenol 2.2'-Methylene bis(6-tert-butyl-4-methylphenol) 3g [119-47-1] 2-tert-Butyl-6-[(3-tert-butyl-2-hydroxy-5-methylphenyl)methyl]-4-methylphenol Cresol, 6,6'-di-tert-butyl-2,2'-methylenedi- 2,2'-Bis-6-terc.butyl-p-kresylmethan 2,2'-Methylenebis 6-(1,1-dimethylethyl)-4-methyl-phenol 2,2'-Methylene-bis-(4-methyl-6-t-butylphenol) 2,2'-Methylenebis(6-(1,1-dimethylethyl)-p-cresol) 2,2'Methylenebis(6-tert-4-methylphenol) 2246ane diglycidyl ether A-22-46 a22-46 Advastab 405 advastab405 Agidol 2 Alterungsschutzmittel BKF Antage W 400 antagew400 Anti Ox antiox Antioxidant BKF Antioxidant NG-2246 Antioxidant OMB antioxidant1 antioxidantbkf antioxidantng2246 antioxidantng-2246 AO 1 AO 1 (Antioxidant) AO 2246 ao1 ao1(antioxidant) ao1[antioxidant] Bis(6-hydroxy-3-methyl-5-tert-butylphenyl)methane Bisaklofen bp bisaklofenbp Bisalkofen BP bisalkofenbp Calco 2246 calco2246 CAO 14 CAO 5