YVAD-CHO (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- YVAD-CHO (trifluoroacetate salt)
- Synonyms
- YVAD-CHO (trifluoroacetate salt)
- CBNumber:
- CB84815369
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
YVAD-CHO (trifluoroacetate salt) price More Price(2)
YVAD-CHO (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO (Item No. 10016).1 It prevents ICE-like and CPP32-like proteinase activity and inhibits apoptosis induced by ceramide or irinotecan (CPT-11; Item No. 14180) in 4B1 cells when used at a concentration of 600 µM. YVAD-CHO (100 µM) also prevents chromogranin A-induced cell death of primary rat microglia but not primary rat cerebellar granule neurons.2WARNING This product is not for human or veterinary use.
References
[1] ATSUSHI SUZUKI . Sequential Operation of Ceramide Synthesis and ICE Cascade in CPT-11-Initiated Apoptotic Death Signaling[J]. Experimental cell research, 1997, 233 1: Pages 41-47. DOI: 10.1006/excr.1997.3498
[2] P. J. KINGHAM J. M P M L Cuzner. Apoptotic Pathways Mobilized in Microglia and Neurones as a Consequence of Chromogranin A-Induced Microglial Activation[J]. Journal of Neurochemistry, 2002, 73 2: 538-547. DOI: 10.1046/j.1471-4159.1999.0730538.x
YVAD-CHO (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
YVAD-CHO (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
