t-Boc-N-amido-PEG2-NHS ester
- CAS No.
- 2183440-73-3
- Chemical Name:
- t-Boc-N-amido-PEG2-NHS ester
- Synonyms
- BocNH-PEG2-CH2CH2COONHS;Boc-NH-PEG2-C2-NHS ester;t-Boc-N-amido-PEG2-NHS ester;2,5-Dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oate;4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-, 2,5-dioxo-1-pyrrolidinyl ester;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]propanoate;BocNH-PEG2-CH2CH2COONHS/4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB84849669
- Molecular Formula:
- C16H26N2O8
- Molecular Weight:
- 374.39
- MDL Number:
- MFCD31381627
- MOL File:
- 2183440-73-3.mol
| Density | 1.24±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Storage temp. -20°C |
| solubility | Soluble in DCM |
| pka | 12.22±0.46(Predicted) |
| form | Solid |
| color | White to off-white |
| InChI | InChI=1S/C16H26N2O8/c1-16(2,3)25-15(22)17-7-9-24-11-10-23-8-6-14(21)26-18-12(19)4-5-13(18)20/h4-11H2,1-3H3,(H,17,22) |
| InChIKey | FNZXIPYAXFROBS-UHFFFAOYSA-N |
| SMILES | C(ON1C(=O)CCC1=O)(=O)CCOCCOCCNC(=O)OC(C)(C)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
t-Boc-N-amido-PEG2-NHS ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS107911 | BocNH-PEG2-CH2CH2COONHS 97% | 2183440-73-3 | 250mg | $283 | 2021-12-16 | Buy |
| BroadPharm | BP-23961 | t-Boc-N-amido-PEG2-NHSester 98% | 2183440-73-3 | 100mg | $320 | 2021-12-16 | Buy |
| Activate Scientific | AS107911 | BocNH-PEG2-CH2CH2COONHS 97% | 2183440-73-3 | 1g | $580 | 2021-12-16 | Buy |
| Matrix Scientific | 179891 | 3-[2-(2-tert-Butoxycarbonylamino-ethoxy)-ethoxy]-propionic acid 2,5-dioxopyrrolidin-1-yl ester 95% | 2183440-73-3 | 1g | $826 | 2021-12-16 | Buy |
| BroadPharm | BP-23961 | t-Boc-N-amido-PEG2-NHSester 98% | 2183440-73-3 | 500mg | $890 | 2021-12-16 | Buy |
t-Boc-N-amido-PEG2-NHS ester Chemical Properties,Uses,Production
Description
t-Boc-N-amido-PEG2-NHS ester is a PEG linker containing an NHS ester and a t-Boc protected amine group. The hydrophilic PEG spacer increases the solubility of compounds in aqueous media. The t-Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-amido-PEG2-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
t-Boc-N-amido-PEG2-NHS ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32433 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Compound Net Biotechnology Inc. | +8615303909093 | sales@compound-net.com | China | 2914 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28785 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4952 | 58 |
| Beijing Minruida Technology Co., Ltd. | 010-82387566 18001021521; | sales@mreda.com.cn | China | 10083 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1992 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 55000 | 58 |
View Lastest Price from t-Boc-N-amido-PEG2-NHS ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-21 | Boc-NH-PEG2-C2-NHS ester
2183440-73-3
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | t-Boc-N-amido-PEG2-NHS ester
2183440-73-3
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Boc-NH-PEG2-C2-NHS ester
2183440-73-3
- US $0.00 / mg
- TargetMol Chemicals Inc.
-
- t-Boc-N-amido-PEG2-NHS ester
2183440-73-3
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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