Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-

2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-

2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- Structure
2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- structure
CAS No.
790652-68-5
Chemical Name:
2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-
Synonyms
Lenalidomide-4-aminomethyl;3-[4-(Aminomethyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione;3-[7-(aminomethyl)-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione;3-[4-(Aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione;3-[4-(aminomethyl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione;2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-;3-[4-(Aminomethyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione?, Lenalidomide-4-aminomethyl
CBNumber:
CB85484342
Molecular Formula:
C14H15N3O3
Molecular Weight:
273.29
MDL Number:
MFCD32201918
MOL File:
790652-68-5.mol
MSDS File:
SDS
Last updated:2025-04-18 09:53:02
Request For Quotation

2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- Properties

Boiling point 594.9±50.0 °C(Predicted)
Density 1.400±0.06 g/cm3(Predicted)
pka 10.72±0.40(Predicted)

2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Ambeed A1224137 Lenalidomide-4-aminomethyl 95% 790652-68-5 1g $586 2026-06-05 Buy
ACHEMBLOCK AD271538 3-(4-(Aminomethyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione 95% 790652-68-5 100MG $805 2026-05-27 Buy
ACHEMBLOCK AD271538 3-(4-(Aminomethyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione 95% 790652-68-5 250MG $1450 2026-05-27 Buy
ACHEMBLOCK AD271538 3-(4-(Aminomethyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione 95% 790652-68-5 1G $3350 2026-05-27 Buy
Chemenu CM327918 3-[7-(aminomethyl)-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione 95%+ 790652-68-5 50g $469 2026-05-26 Buy
Product number Packaging Price Buy
A1224137 1g $586 Buy
AD271538 100MG $805 Buy
AD271538 250MG $1450 Buy
AD271538 1G $3350 Buy
CM327918 50g $469 Buy

2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- Chemical Properties,Uses,Production

Uses

Lenalidomide-4-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl can be connected to the ligand for protein by a linker to form PROTAC[1].

IC 50

Cereblon

References

[1] Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. DOI:10.1016/j.csbj.2019.01.006
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
Lianyungang TengFa Biological Technology Co. Ltd 0518-85475186 18705131893 wang666xt@163.com China 351 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Henan Alfachem Co.,Ltd. 0371-55051623 18137891487 3983243027@qq.com China 9965 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3925 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9067 58
Abosyn 0512-69561983 13914027025 he_qf@medinoah.com China 3000 58
Hangzhou Bingochem Co., Ltd. 0571-87658025 sales@bingochem.com China 21532 58
Pharmalego 18321033991 marketing@pharmalego.com China 4109 58
Supplier Advantage
Daicel Chiral Technologies (China)CO.,LTD 65
Lianyungang TengFa Biological Technology Co. Ltd 55
Amadis Chemical Company Limited 58
Henan Alfachem Co.,Ltd. 58
SuZhou Medinoah Co.,LTD. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Abosyn 58
Hangzhou Bingochem Co., Ltd. 58
Pharmalego 58

790652-68-5(2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-)Related Search:

Thalidomide CC-885 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Pomalidomide
CC220

1of2

2,6-Piperidinedione, 3-[4-(aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]- 3-[4-(Aminomethyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione Lenalidomide-4-aminomethyl 3-[7-(aminomethyl)-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione 3-[4-(aminomethyl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione 3-[4-(Aminomethyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione?, Lenalidomide-4-aminomethyl 3-[4-(Aminomethyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione 790652-68-5 E3 ligase Ligan