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ChemicalBook >> CAS DataBase List >>Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]-

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]-

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- Structure
Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- structure
CAS No.
1606974-33-7
Chemical Name:
Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]-
Synonyms
Zatolmilast;BPN14770;Zatolmilast (BPN14770);Zatolmilast, 10 mM in DMSO;Zatolmilast (BPN14770) ，S6844;Zatolmilast,Phosphodiesterase (PDE),BPN-14770,Inhibitor,BPN 14770,inhibit;2-(4-{[2-(3-chlorophenyl)-6-(trifluoromethyl)pyridin-4-yl]methyl}phenyl)acetic acid;Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]-;4-[[2-(3-Chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]benzeneacetic acid (ACI)
CBNumber:
CB85552252
Molecular Formula:
C21H15ClF3NO2
Molecular Weight:
405.8
MDL Number:
MFCD32067916
MOL File:
1606974-33-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
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Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- Properties

Boiling point 514.4±50.0 °C(Predicted)
Density 1.351±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 260 mg/mL (640.71 mM)
pka 4.27±0.10(Predicted)
form Solid
color White to off-white
FDA UNII G786V328X6

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 34075 BPN14770 ≥98% 1606974-33-7 1mg $72 2026-04-30 Buy
Cayman Chemical 34075 BPN14770 ≥98% 1606974-33-7 5mg $323 2026-04-30 Buy
Cayman Chemical 34075 BPN14770 ≥98% 1606974-33-7 10mg $572 2026-04-30 Buy
Cayman Chemical 34075 BPN14770 ≥98% 1606974-33-7 25mg $1073 2026-04-30 Buy
Biosynth GPC97433 BPN14770 1606974-33-7 5mg $590 2026-06-04 Buy
Product number Packaging Price Buy
34075 1mg $72 Buy
34075 5mg $323 Buy
34075 10mg $572 Buy
34075 25mg $1073 Buy
GPC97433 5mg $590 Buy

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- Chemical Properties, Uses, Production

Uses

Zatolmilast is a selective phosphodiesterase 4D (PDE4D) allosteric inhibitor for the treatment of fragile X syndrome and other brain disorders.

in vivo

Zatolmilast increases brain cAMP, increases phosphorylation of CREB and increases production of brain-derived neurotrophic factor (BDNF) in hippocampus[1].
Zatolmilast (0.1-30 mg/kg; p.o.; 24 hours) provides cognitive benefit in the mouse novel object recognition (NOR) at doses above 0.3 mg/kg[2].

Animal Model:C57Bl6 mice[2]
Dosage:0.1, 0.3, 1, 3, 10, 30 mg/kg
Administration:p.o.; 24hours
Result:Significantly improved novel object discrimination at doses above 0.3 mg/kg.

IC 50

PDE4D3: 7.4 nM (IC50); PDE4D7: 7.8 nM (IC50)

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- Suppliers

Global Suppliers ( 48)
Supplier Tel Email Country ProdList Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 sales@sun-shinechem.com China 1197 64
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239 3193328036@qq.com China 28150 68
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Dongyang Biotechnology Co., Ltd. 0512-13601744364 13601744364 chemsharker@126.com China 1160 58
Supplier Advantage
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai Beckham Medical Technology Co., Ltd 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Chaolan Chemical Technology Center 58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
TargetMol Chemicals Inc. 58
Shanghai Dongyang Biotechnology Co., Ltd. 58

View Latest Price from Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Zatolmilast pictures 2026-07-14 Zatolmilast
1606974-33-7
 $64.00-257.00 99.31% 10g TargetMol Chemicals Inc.
Zatolmilast pictures 2026-07-14 Zatolmilast
1606974-33-7
 $64.00-257.00 99.31% 10g TargetMol Chemicals Inc.
BPN14770 pictures 2025-09-01 BPN14770
1606974-33-7
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
  • Zatolmilast pictures
  • Zatolmilast
    1606974-33-7
  • $64.00-257.00
  • 99.31%
  • TargetMol Chemicals Inc.
  • Zatolmilast pictures
  • Zatolmilast
    1606974-33-7
  • $64.00-257.00
  • 99.31%
  • TargetMol Chemicals Inc.
  • BPN14770 pictures
  • BPN14770
    1606974-33-7
  • $1.00
  • 99%
  • Shaanxi Dideu Medichem Co. Ltd

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- Spectrum

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]-(1606974-33-7)1HNMR

1606974-33-7 (Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]-) Related Search:

Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- THPP-1 Bay 60-7550 PDE1-IN-1 (phosphate) 4-(azetidin-1-yl)-7-methyl-5-{1-methyl-5-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-4-yl}imidazo[5,1-f][1,2,4]triazine
GSK-356278

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Benzeneacetic acid, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]- Zatolmilast,Phosphodiesterase (PDE),BPN-14770,Inhibitor,BPN 14770,inhibit 2-(4-{[2-(3-chlorophenyl)-6-(trifluoromethyl)pyridin-4-yl]methyl}phenyl)acetic acid Zatolmilast, 10 mM in DMSO Zatolmilast (BPN14770) Zatolmilast (BPN14770) ，S6844 BPN14770 Zatolmilast 4-[[2-(3-Chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]benzeneacetic acid (ACI) 1606974-33-7 C21H15ClF3NO2