2,2,6,6-Tetramethyl-4-piperidone monohydrate
- CAS No.
- 10581-38-1
- Chemical Name:
- 2,2,6,6-Tetramethyl-4-piperidone monohydrate
- Synonyms
- TRIACETONEAMINE HYDRATE;Triacetonamine monohydrate;2,2,6,6-TetraMethyl-4-piperidone Hydrate;2,2,6,6-Tetramethyl-4-piperidone monohydrate;2,2,6,6-Tetramethyl-4-Piperidone/Tripyruvalamine;4-Piperidinone, 2,2,6,6-tetramethyl-, monohydrate
- CBNumber:
- CB8663706
- Molecular Formula:
- C9H19NO2
- Molecular Weight:
- 173.25
- MDL Number:
- MFCD00149393
- MOL File:
- 10581-38-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P301+P310a-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| TSCA | Yes | |||||||||
| NFPA 704 |
|
2,2,6,6-Tetramethyl-4-piperidone monohydrate price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0145555 | Triacetonamine (monohydrate) ≥98% | 10581-38-1 | 500g | $178 | 2026-06-04 | Buy |
| AK Scientific | J99091 | 2,2,6,6-Tetramethyl-4-piperidone monohydrate 97% | 10581-38-1 | 5g | $12 | 2026-06-04 | Buy |
| AK Scientific | J99091 | 2,2,6,6-Tetramethyl-4-piperidone monohydrate 97% | 10581-38-1 | 25g | $22 | 2026-06-04 | Buy |
| AK Scientific | J99091 | 2,2,6,6-Tetramethyl-4-piperidone monohydrate 97% | 10581-38-1 | 100g | $41 | 2026-06-04 | Buy |
| AK Scientific | J99091 | 2,2,6,6-Tetramethyl-4-piperidone monohydrate 97% | 10581-38-1 | 500g | $120 | 2026-06-04 | Buy |
2,2,6,6-Tetramethyl-4-piperidone monohydrate Chemical Properties, Uses, Production
Uses
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats[1][2].
in vivo
Triacetonamine (Purchased from MCE; 200 mg, 300 mg, 400 mg/Kg/day; gavage; 2 days) monohydrate shows typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality[2].
| Animal Model: | Rats (half male and female, 6-8 weeks old, 200±10 g)[2] |
| Dosage: | 200 mg, 300 mg, 400 mg/Kg |
| Administration: | Gavage; daily; 2 days |
| Result: | Showed typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality. |
References
[1] Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010;101(11):4242-4245. DOI:10.1016/j.biortech.2010.01.031
[2] Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010 Jun;101(11):4242-5. DOI:10.1016/j.biortech.2010.01.031
[3] Ting Jiang, et al. Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide. Tissue Eng Regen Med. 2022 Apr;19(2):403-415. DOI:10.1007/s13770-021-00421-5
2,2,6,6-Tetramethyl-4-piperidone monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Guangzhou Jhd Chemical Reagent Co., Ltd. | 020-84383047 | sales@jhd.com.cn | China | 9177 | 65 |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 9998 | 58 | |
| 9ding chemical ( Shanghai) Limited | 021-021-52271985 17721149837 | sales@9dingchem.com | China | 19780 | 60 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Guangdong Fangxin Biotechnology Co., Ltd. | 0751-2838688 13376594225 | 1276075424@qq.com | China | 9930 | 58 |
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