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Cefepime hydrochloride

CAS No.
123171-59-5
Chemical Name:
Cefepime hydrochloride
Synonyms
Maxipime;Cefepime Hydrocloride;Cefepim dihydrochloride;CefepiMe dihydrochloride hydrate;Cefepime dihydrochloride monohydrate for system suitability CRS;Axepim;Cepimex;CEPEFIME HCL;Cefepime 2HCl;efepime hydrochloride
CBNumber:
CB8691453
Molecular Formula:
C19H28Cl2N6O6S2
Molecular Weight:
571.49
MDL Number:
MFCD06795759
MOL File:
123171-59-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-20 20:20:01

Cefepime hydrochloride Properties

Melting point 150°C (dec.)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Soluble in DMSO
form powder
color white to faint yellow
Sensitive Light Sensitive
Major Application pharmaceutical (small molecule)
InChIKey LRAJHPGSGBRUJN-ZVMPLFRQNA-N
SMILES C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)C[N+]1(CCCC1)C)(=O)O.[Cl-].Cl.O |&1:5,7,r|
CAS DataBase Reference 123171-59-5(CAS DataBase Reference)
FDA UNII I8X1O0607P
NCI Drug Dictionary cefepime hydrochloride
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Warning
Hazard statements  H317-H334
Precautionary statements  P261-P280g-P284-P304+P340-P342+P311a-P501a
Hazard Codes  Xi
Risk Statements  36/37/38-42/43
Safety Statements  22-26-36/37/39
WGK Germany  3
HS Code  29419000
Storage Class 11 - Combustible Solids
NFPA 704
0
3 0

Cefepime hydrochloride price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000634 Cefepime dihydrochloride monohydrate for system suitability European Pharmacopoeia (EP) Reference Standard 123171-59-5 15 mg $176 2026-04-30 Buy
Sigma-Aldrich Y0000633 Cefepime dihydrochloride monohydrate European Pharmacopoeia (EP) Reference Standard 123171-59-5 160 mg $254 2026-04-30 Buy
Sigma-Aldrich A3737 Cefepime hydrochloride ≥98% (HPLC) 123171-59-5 100mg $693 2026-04-30 Buy
Sigma-Aldrich 1097636 Cefepime hydrochloride 123171-59-5 500mg $440 2026-04-30 Buy
TCI Chemical C3565 Cefepime Dihydrochloride Monohydrate 123171-59-5 1G $87 2026-04-30 Buy
Product number Packaging Price Buy
Y0000634 15 mg $176 Buy
Y0000633 160 mg $254 Buy
A3737 100mg $693 Buy
1097636 500mg $440 Buy
C3565 1G $87 Buy

Cefepime hydrochloride Chemical Properties, Uses, Production

Chemical Properties

White to pale yellow powder

Uses

antipsoriatic, protein synthesis inhibitor

Uses

Cefepime hydrochloride monohydrate is used as a broad spectrum antibiotic targeting a wide variety of naturally antibiotic resistant Gram-positive and Gram-negative bacteria. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases.

Uses

Semisynthetic, fourth generation cephalosporin antibiotic. Antibacterial

Definition

ChEBI: A hydrochloride that is the monohydrate of the dihydrochloride salt of cefepime.

Synthesis

At room temperature (15-25C), 171g of sodium isocaproate (1.03 mol) was dissolved in 900mL of water and 200mL of acetone, and 300g of cefepime sulfate (0.52 mol, weight by weight in anhydrous) was added in batches with effective stirring to form a well-flowing slurry system. 1600mL of acetone and an appropriate amount of activated charcoal were added after 10 minutes and stirred for 30 minutes. The solid was separated by centrifugation or diafiltration. The filter cake was washed with 500 mL of a mixed acetone-water 2:1 (v/v) solution and the filtrates were combined. 18% HCl was added to the filtrate with stirring to pH 1.0 to 1.5. 8 L of acetone was then added over 1 hr. The system was cooled down again to 5 to 10C and stirring was continued for 1 hr. Filter extraction. The filter cake was washed with acetone and dried under vacuum at 40C to give about 270 g of white crystalline powder. Purity 99.7%, water content 3.8% (K-F method), acetone residue 0.25%. The product is cefepime dichlorohydrate monohydrate, i.e. cefepime hydrochloride. All quality indicators meet the requirements of the U.S. Pharmacopeia.

Cefepime hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 377)
Supplier Tel Email Country ProdList Advantage
Jinan Yunding Biotechnology Co., Ltd 15662712965 1013429786@qq.com China 31 58
Hubei Weideli Chemical Reagent Co., Ltd. 027-83984790 17720532645 t17720532645@163.com China 963 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50

View Latest Price from Cefepime hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
 Cefepime Hydrochloride pictures 2026-09-01 Cefepime Hydrochloride
123171-59-5
1Kg 99% 10kg Shaanxi TNJONE Pharmaceutical Co., Ltd
Cefepime Dihydrochloride Monohydrate pictures 2026-08-20 Cefepime Dihydrochloride Monohydrate
123171-59-5
$39.00 99.94% 10g TargetMol Chemicals Inc.
Cefepime Dihydrochloride Monohydrate pictures 2026-07-15 Cefepime Dihydrochloride Monohydrate
123171-59-5
$39.00 99.94% 10g TargetMol Chemicals Inc.

Cefepime hydrochloride Spectrum

Cefepim dihydrochloride Pyrrolidinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride, monohydrochloride, monohydrate Pyrrolidinium, 1-[[7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride, monohydrochloride, monohydrate, [6R-[6α,7β(Z)]]- (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-[1-(1-methylpyrrolidinyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid hydrochloride monohydrate Cefepime hydrochloride 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[(1-methyl-1-pyrrolidin-1-iumyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride Cefepime Hydrochloride Crude (4.2.0)oct-2-en-3-yl)methyl)-1-methylpyrrolidinium chloride, 7(sup 2)-(Z)-(O-methyloxime), monohydrochloride, monohydrate Cefepime 2HCl Cefepime Hydrochloride (500 mg) Cefepime Hydrochloride (500 mg)G0D116860ug/mg(an) CefepiMe dihydrochloride hydrate 1-[[(6R,7R)-7-[[(2Z)-(2-AMino-4-thiazolyl)(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]-1-MethylpyrrolidiniuM Inner Salt Dihydrochloride Monohydrate 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl- pyrrolidinium Inner Salt Hydrochloride Monohydrate Axepim Cefepime Hydrochloride Monohydrate Cepimex Maxipime Cefepime Dihydrochloride(sterile) PyrrolidiniuM,1-[[(6R,7R)-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]-1-Methyl-,chloride, hydrochloride, hydrate (1:1:1:1) efepime hydrochloride Cefepime Hydrocloride Cefepime (hydrochloride hydrate) Cefepime dihydrochloride monohydrate for system suitability CRS Cefepime dihydrochloride monohydrate CRS Cefepime Dihydrochloride Monohydrat 1-(((6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-methylpyrrolidin-1-ium chloride hydrochloride hydrate Cefepime hydrochloride USP/EP/BP Cefepime dihydrochloride monohydrate for system suitability (Y0000634) Cefepime HydrochlorideQ: What is Cefepime Hydrochloride Q: What is the CAS Number of Cefepime Hydrochloride Q: What is the storage condition of Cefepime Hydrochloride Q: What are the applications of Cefepime Hydrochloride 123171-59-5 Cefepime hydrochloride Cefepime Hydrochloride (1097636) Cefepime hydrochlorider Cefepime dihydrochloridum monohydricum Cefepime dihydrochloride salt monohydrate Cefepime Dihydrochloride Monohydrate,Bacterial,Antibiotic,inhibit,Cefepime Dihydrochloride,Inhibitor Cefepime 2HCl monohydrate Cefpixime Hydrochloride Cefepime hydrochloride/Cefepime hydrochloride Cefepime hydrochloride,NA CEPEFIME HCL Cefepime Dihydrochloride Monohydrate, 10 mM in DMSO CEFEPIME HYDROCHLORIDE (BUFFERED WITH ARGININE) Cefepime dihydrochloride monohydrate, Antibiotic for Culture Media Use Only Cefepime Dihydrochloride RS 1-(((6R,7R)-7-((Z)-2-(2-Amino-thiazol-4-yl)-2-(methoxyimino)-acetcarboxcarboxcarboxamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-methylpyrrolidin-1-ium chloride HCl hydrate 123171-59-5 C20H29Cl2N5O6S2 C19H24N6O5S2xHCl C19H27ClN6O6S2 C19H25ClN6O5S2HClH2O C19H28Cl2N6O6S2 Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds Heterocyclic Compounds