Cefepime hydrochloride
- CAS No.
- 123171-59-5
- Chemical Name:
- Cefepime hydrochloride
- Synonyms
- Maxipime;Cefepime Hydrocloride;Cefepim dihydrochloride;CefepiMe dihydrochloride hydrate;Cefepime dihydrochloride monohydrate for system suitability CRS;Axepim;Cepimex;CEPEFIME HCL;Cefepime 2HCl;efepime hydrochloride
- CBNumber:
- CB8691453
- Molecular Formula:
- C19H28Cl2N6O6S2
- Molecular Weight:
- 571.49
- MDL Number:
- MFCD06795759
- MOL File:
- 123171-59-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 150°C (dec.) |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Soluble in DMSO |
| form | powder |
| color | white to faint yellow |
| Sensitive | Light Sensitive |
| Major Application | pharmaceutical (small molecule) |
| InChIKey | LRAJHPGSGBRUJN-ZVMPLFRQNA-N |
| SMILES | C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)C[N+]1(CCCC1)C)(=O)O.[Cl-].Cl.O |&1:5,7,r| |
| CAS DataBase Reference | 123171-59-5(CAS DataBase Reference) |
| FDA UNII | I8X1O0607P |
| NCI Drug Dictionary | cefepime hydrochloride |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H334 | |||||||||
| Precautionary statements | P261-P280g-P284-P304+P340-P342+P311a-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-42/43 | |||||||||
| Safety Statements | 22-26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29419000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Cefepime hydrochloride price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000634 | Cefepime dihydrochloride monohydrate for system suitability European Pharmacopoeia (EP) Reference Standard | 123171-59-5 | 15 mg | $176 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0000633 | Cefepime dihydrochloride monohydrate European Pharmacopoeia (EP) Reference Standard | 123171-59-5 | 160 mg | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | A3737 | Cefepime hydrochloride ≥98% (HPLC) | 123171-59-5 | 100mg | $693 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1097636 | Cefepime hydrochloride | 123171-59-5 | 500mg | $440 | 2026-04-30 | Buy |
| TCI Chemical | C3565 | Cefepime Dihydrochloride Monohydrate | 123171-59-5 | 1G | $87 | 2026-04-30 | Buy |
Cefepime hydrochloride Chemical Properties, Uses, Production
Chemical Properties
White to pale yellow powder
Uses
antipsoriatic, protein synthesis inhibitor
Uses
Cefepime hydrochloride monohydrate is used as a broad spectrum antibiotic targeting a wide variety of naturally antibiotic resistant Gram-positive and Gram-negative bacteria. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases.
Uses
Semisynthetic, fourth generation cephalosporin antibiotic. Antibacterial
Definition
ChEBI: A hydrochloride that is the monohydrate of the dihydrochloride salt of cefepime.
Synthesis
At room temperature (15-25C), 171g of sodium isocaproate (1.03 mol) was dissolved in 900mL of water and 200mL of acetone, and 300g of cefepime sulfate (0.52 mol, weight by weight in anhydrous) was added in batches with effective stirring to form a well-flowing slurry system. 1600mL of acetone and an appropriate amount of activated charcoal were added after 10 minutes and stirred for 30 minutes. The solid was separated by centrifugation or diafiltration. The filter cake was washed with 500 mL of a mixed acetone-water 2:1 (v/v) solution and the filtrates were combined. 18% HCl was added to the filtrate with stirring to pH 1.0 to 1.5. 8 L of acetone was then added over 1 hr. The system was cooled down again to 5 to 10C and stirring was continued for 1 hr. Filter extraction. The filter cake was washed with acetone and dried under vacuum at 40C to give about 270 g of white crystalline powder. Purity 99.7%, water content 3.8% (K-F method), acetone residue 0.25%. The product is cefepime dichlorohydrate monohydrate, i.e. cefepime hydrochloride. All quality indicators meet the requirements of the U.S. Pharmacopeia.
Cefepime hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Yunding Biotechnology Co., Ltd | 15662712965 | 1013429786@qq.com | China | 31 | 58 |
| Hubei Weideli Chemical Reagent Co., Ltd. | 027-83984790 17720532645 | t17720532645@163.com | China | 963 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
View Latest Price from Cefepime hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-01 | Cefepime Hydrochloride
123171-59-5
|
1Kg | 99% | 10kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | ||
![]() |
2026-08-20 | Cefepime Dihydrochloride Monohydrate
123171-59-5
|
$39.00 | 99.94% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2026-07-15 | Cefepime Dihydrochloride Monohydrate
123171-59-5
|
$39.00 | 99.94% | 10g | TargetMol Chemicals Inc. |
-

- Cefepime Hydrochloride
123171-59-5
- $0.00
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-

- Cefepime Dihydrochloride Monohydrate
123171-59-5
- $39.00
- 99.94%
- TargetMol Chemicals Inc.
-

- Cefepime Dihydrochloride Monohydrate
123171-59-5
- $39.00
- 99.94%
- TargetMol Chemicals Inc.





