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MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH

MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH structure

CAS No.: 323577-36-2

Chemical Name:: MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH

Synonyms: MCA-(ALA7,LYS(DNP)9)-BRADYKININ;MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH;Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt;7-Methoxycoumarin-4-acetyl [Ala7-(2,4-Dinitrophenyl)Lys9]-Bradykinin;Matrix metalloproteinases MMP FRET Substrate V, bradykinin Mca- (Ala?, Lys(Dnp)?;(7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(2,4-dinitrophenyl);N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine;L-Lysine, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-

CBNumber:: CB8693396

Molecular Formula:: C66H81N15O19

Molecular Weight:: 1388.44

MDL Number:: MFCD03093413

MOL File:: 323577-36-2.mol

MSDS File:: SDS

Last updated:2026-09-12 18:55:51

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MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH Properties

Density	1.48±0.1 g/cm3(Predicted)
storage temp.	-15°C
pka	3.38±0.10(Predicted)
form	Solid
color	Light yellow to yellow
Appearance	White or Off-white Lyophilized Powder

MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH price More Price(11)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FM110950	Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt	323577-36-2	500ug	$900	2026-06-04	Buy
Biosynth	FM110950	Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt	323577-36-2	250ug	$900	2026-06-04	Buy
Biosynth	FM110950	Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt	323577-36-2	100ug	$900	2026-06-04	Buy
Biosynth	FM110950	Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt	323577-36-2	1000ug	$1320	2026-06-04	Buy
Biosynth	FM110950	Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt	323577-36-2	2000ug	$2280	2026-06-04	Buy

Product number	Packaging	Price	Buy
FM110950	500ug	$900	Buy
FM110950	250ug	$900	Buy
FM110950	100ug	$900	Buy
FM110950	1000ug	$1320	Buy
FM110950	2000ug	$2280	Buy

MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH Chemical Properties, Uses, Production

Description

Mca-(Ala7,Lys(Dnp)9)-Bradykinin is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1), a membrane-bound zinc metallopeptidase related to neprilysin in amino acid sequence. It is used as a substrate for insulin-degrading enzymes (IDE) and ACE2.

Uses

Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage[1].

References

[1] Johnson GD, et al. Development of an internally quenched fluorescent substrate selective for endothelin-converting enzyme-1. Anal Biochem. 2000 Nov 1;286(1):112-8. DOI:10.1006/abio.2000.4772

Sequene

Mca-RPPGFSAFK(Dnp)

MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH Suppliers

Global Suppliers ( 47)

Supplier	Tel	Email	Country	ProdList	Advantage
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
Creative Peptides		info@creative-peptides.com	United States	6083	56
Nanjing Leon Biological Technology Co., Ltd.	025-84523390 -127; 17705183659	sales@njleonbiotech.com	China	5501	55
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19087	58

Supplier	Advantage
GL Biochem (Shanghai) Ltd	64
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Creative Peptides	56
Nanjing Leon Biological Technology Co., Ltd.	55
Nanjing Peptide Biotech Ltd.	55
Hangzhou Peptidego Biotech Co.,Ltd.	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	58

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MCA-(ALA7,LYS(DNP)9)-BRADYKININ L-Lysine, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)- N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine (7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(2,4-dinitrophenyl) 7-Methoxycoumarin-4-acetyl [Ala7-(2,4-Dinitrophenyl)Lys9]-Bradykinin Matrix metalloproteinases MMP FRET Substrate V, bradykinin Mca- (Ala?, Lys(Dnp)? Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt MCA-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH 323577-36-2