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MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH

MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH structure

CAS No.: 323577-36-2

Chemical Name:: MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH

Synonyms: MCA-(ALA7,LYS(DNP)9)-BRADYKININ;MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH;Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt;7-Methoxycoumarin-4-acetyl [Ala7-(2,4-Dinitrophenyl)Lys9]-Bradykinin;Matrix metalloproteinases MMP FRET Substrate V, bradykinin Mca- (Ala?, Lys(Dnp)?;(7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(2,4-dinitrophenyl);N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine;L-Lysine, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-

CBNumber:: CB8693396

Molecular Formula:: C66H81N15O19

Molecular Weight:: 1388.44

MDL Number:: MFCD03093413

MOL File:: 323577-36-2.mol

MSDS File:: SDS

Last updated:2025-08-05 17:23:13

Product description	Number	Pack Size	Price
MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH 95.00%	PEP0009406	5MG	$501.9
Mca-(Ala7,Lys(Dnp)9)-Bradykinintrifluoroacetatesalt	32995	1MG	$523
Mca-(Ala7,Lys(Dnp)9)-Bradykinintrifluoroacetatesalt	32995	5MG	$2088.49

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MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH Properties

Density	1.48±0.1 g/cm3(Predicted)
storage temp.	-15°C
form	Solid
pka	3.38±0.10(Predicted)
color	Light yellow to yellow
Appearance	White or Off-white Lyophilized Powder

MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	PEP0009406	MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH 95.00%	323577-36-2	5MG	$501.9	2021-12-16	Buy
Chem-Impex	32995	Mca-(Ala7,Lys(Dnp)9)-Bradykinintrifluoroacetatesalt	323577-36-2	1MG	$523	2021-12-16	Buy
Chem-Impex	32995	Mca-(Ala7,Lys(Dnp)9)-Bradykinintrifluoroacetatesalt	323577-36-2	5MG	$2088.49	2021-12-16	Buy

Product number	Packaging	Price	Buy
PEP0009406	5MG	$501.9	Buy
32995	1MG	$523	Buy
32995	5MG	$2088.49	Buy

MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH Chemical Properties,Uses,Production

Description

Mca-(Ala7,Lys(Dnp)9)-Bradykinin is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1), a membrane-bound zinc metallopeptidase related to neprilysin in amino acid sequence. It is used as a substrate for insulin-degrading enzymes (IDE) and ACE2.

Uses

Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage[1].

References

[1] Johnson GD, et al. Development of an internally quenched fluorescent substrate selective for endothelin-converting enzyme-1. Anal Biochem. 2000 Nov 1;286(1):112-8. DOI:10.1006/abio.2000.4772

Sequene

Mca-RPPGFSAFK(Dnp)

MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH Suppliers

Global( 46)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Nanjing TGpeptide	+86-13347807150	support@tgpeptide.com	China	3279	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5218	58
Shanghai Hanhong Scientific Co., Ltd.	+undefined17612118332	Lucky@hanhonggroup.com	China	5844	58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.	+8615051830413	sales.njleonbiotech@gmail.com	China	5482	58
DONBOO AMINO ACID COMPANY	+8618051385538	donboo@donboo.com	China	9363	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Career Henan Chemica Co	58
Chengdu Youngshe Chemical Co., Ltd.	58
Nanjing TGpeptide	58
Aladdin Scientific	58
Changsha MOL Changes Biotechnology Co., Ltd.	58
Shanghai Hanhong Scientific Co., Ltd.	58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.	58
DONBOO AMINO ACID COMPANY	58
GL Biochem (Shanghai) Ltd	64

MCA-(ALA7,LYS(DNP)9)-BRADYKININ MCA-ARG-PRO-PRO-GLY-PHE-SER-ALA-PHE-LYS(DNP)-OH L-Lysine, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)- N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine (7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(2,4-dinitrophenyl) 7-Methoxycoumarin-4-acetyl [Ala7-(2,4-Dinitrophenyl)Lys9]-Bradykinin Matrix metalloproteinases MMP FRET Substrate V, bradykinin Mca- (Ala?, Lys(Dnp)? Mca-(Ala7,Lys(Dnp)9)-Bradykinin trifluoroacetate salt 323577-36-2