SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
- CAS No.
- 125494-59-9
- Chemical Name:
- SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
- Synonyms
- SIBUTRAMINE HCL MONOHYDRATE;Sibutramine sib;SibutramineHClH2O;SIBUTRAMINE HCL HYDRATE;)-SibutraMine-d6 HCl H2O;BTS-54524, Reductil, Meridia;SIBUTRAMINE HYDROCHLORIDE HYDRATE;Sibutramine hydrochloride solution;Sibutramine Hydrochloride Monohydra;SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
- CBNumber:
- CB8708494
- Molecular Formula:
- C17H29Cl2NO
- Molecular Weight:
- 334.32
- MDL Number:
- MFCD04039806
- MOL File:
- 125494-59-9.mol
- TDS File:
- TDS
| Melting point | 193-195.5°C |
|---|---|
| Flash point | 9℃ |
| storage temp. | Room temp |
| solubility | DMSO: >30mg/mL |
| form | solid |
| color | white |
| FDA UNII | OGM0YHD1WF |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H301+H311+H331-H370 |
| Precautionary statements | P210-P260-P280-P301+P310-P311 |
| Hazard Codes | Xi,T,F |
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 |
| Safety Statements | 22-24/25-36-26-45-36/37-16-7 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FS27826 | Sibutramine hydrochloride monohydrate | 125494-59-9 | 0.1g | $259.6 | 2026-06-04 | Buy |
| Biosynth | FS27826 | Sibutramine hydrochloride monohydrate | 125494-59-9 | 0.25g | $584.1 | 2026-06-04 | Buy |
| Biosynth | FS27826 | Sibutramine hydrochloride monohydrate | 125494-59-9 | 0.5g | $973.5 | 2026-06-04 | Buy |
| Biosynth | FS27826 | Sibutramine hydrochloride monohydrate | 125494-59-9 | 1g | $1298 | 2026-06-04 | Buy |
| Biosynth | FS27826 | Sibutramine hydrochloride monohydrate | 125494-59-9 | 2g | $2076.8 | 2026-06-04 | Buy |
SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE Chemical Properties,Uses,Production
Description
Sibutramine was introduced as Meridia in the US for the control of obesity, in conjunction with a reduced-calorie diet. Sibutramine can be prepared in four steps from 4-chlorobenzyl cyanide. Sibutramine acts as a serotonin and noradrenaline reuptake inhibitor ; in animal studies, it reduces energy intake by creating a satieted feeling and increases energy expenditure by enhancing thermogenesis. In a clinical study in obese patients treated with 10 or 15 mg of Sibutramine once-daily, meaningful weight loss was sustained for 12 months ; an additional study demonstrated a lack of abuse potential. An appreciable part of Sibutramine's effect would also be due to its 2N-mono and didesmethylmetabolites, which are very potent monoamine reuptake inhibitors themselves.
Chemical Properties
White Solid
Originator
Knoll (Germany)
Uses
A serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure
Uses
antiobesity agent;neurotransmitter reuptake inhibitor
Uses
antihyperlipidemic
brand name
Meridia (Abbott);Meridia, Reductil.
