Cyclobutylmethylamine hydrochloride
- CAS No.
- 5454-82-0
- Chemical Name:
- Cyclobutylmethylamine hydrochloride
- Synonyms
- C-Cyclobutyl-methylamine;CyclobutylMethylaMine, HCl;CyclobutaneMethanaMine HCl;(aMinoMethyl)cyclobutane hcl;Cyclobutylmethylamine hydrochloride;CyclobutaneMethanaMine hydrochloride;1-CyclobutylMethylaMine hydrochloride;(AMinoMethyl)cyclobutane hydrochloride;CyclobutaneMethanaMine, hydrochloride (1:1)
- CBNumber:
- CB1967560
- Molecular Formula:
- C5H12ClN
- Molecular Weight:
- 121.61
- MDL Number:
- MFCD00034952
- MOL File:
- 5454-82-0.mol
- MSDS File:
- SDS
| Melting point | >212°C (dec.) |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Off-White to Pale Beige |
| Stability | Hygroscopic |
| InChI | InChI=1S/C5H11N.ClH/c6-4-5-2-1-3-5;/h5H,1-4,6H2;1H |
| InChIKey | JVZOVVGVPJVLSL-UHFFFAOYSA-N |
| SMILES | C(C1CCC1)N.Cl |
| CAS DataBase Reference | 5454-82-0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| HS Code | 2922390090 |
Cyclobutylmethylamine hydrochloride price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 270608 | Cyclobutylmethanamine hydrochloride Asreported | 5454-82-0 | 1g | $360 | 2026-06-03 | Buy |
| Usbiological | 270608 | Cyclobutylmethanamine hydrochloride Asreported | 5454-82-0 | 2g | $496 | 2026-06-03 | Buy |
| Usbiological | 270608 | Cyclobutylmethanamine hydrochloride Asreported | 5454-82-0 | 5g | $744 | 2026-06-03 | Buy |
| Usbiological | 270608 | Cyclobutylmethanamine hydrochloride Asreported | 5454-82-0 | 10g | $1055 | 2026-06-03 | Buy |
| Usbiological | 270608 | Cyclobutylmethanamine hydrochloride Asreported | 5454-82-0 | 25g | $1770 | 2026-06-03 | Buy |
Cyclobutylmethylamine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White solid
Synthesis
4426-11-3
5454-82-0
General procedure for the synthesis of cyclobutylmethylamine hydrochloride from cyclobutanecarbonitrile: A tetrahydrofuran solution of borane (1 M, 296 mL, 296 mmol) was slowly added to a tetrahydrofuran (60 mL) solution of cyclobutanecarbonitrile (20 g, 247 mmol) under argon protection. The reaction mixture was heated to reflux and kept overnight. Upon completion of the reaction, the mixture was cooled in an ice-water bath and methanol (120 mL) was added slowly and dropwise, controlling the reaction temperature below 20 °C. Subsequently, a methanolic solution of 4M hydrochloric acid (300mL) was added and the temperature continued to be controlled below 20°C. The resulting solution was heated and refluxed for 2.5 hours. At the end of the reaction, the mixture was cooled and concentrated. The residue was diluted with methanol (100 mL) and concentrated again and the process was repeated. Ether was added to the residue, stirred for 30 min and filtered to give the title compound cyclobutylmethylamine hydrochloride (25.9 g, 86% yield) as a white solid. NMR hydrogen spectrum (300 MHz, DMSO-d6) δ ppm: 1.70-1.86 (m, 4H), 1.97-2.04 (m, 2H), 2.46-2.61 (m, 1H), 2.75-2.84 (m, 2H), 8.02 (br s, 3H).
References
[1] Patent: WO2015/25164, 2015, A1. Location in patent: Paragraph 59
[2] Patent: US2015/57298, 2015, A1. Location in patent: Page/Page column 19
[3] Patent: WO2011/97491, 2011, A1. Location in patent: Page/Page column 71-72
[4] Patent: WO2005/75464, 2005, A1. Location in patent: Page/Page column 22
[5] Patent: WO2005/74939, 2005, A1. Location in patent: Page/Page column 59
Cyclobutylmethylamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Nanjing JinruiJiuAn Biotechnology Co., Ltd. | 025-58196018 800028039 | sales@fartop.net | China | 2227 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9336 | 55 |
| Shanghai Famo Bio-chemical Technology Company Ltd. | 02136680027 15800370750 | 1706640024@qq.com | China | 494 | 56 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2853 | 52 |
View Lastest Price from Cyclobutylmethylamine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | Cyclobutylmethylamine hydrochloride
5454-82-0
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2020-01-08 | Cyclobutylmethylamine hydrochloride
5454-82-0
|
1KG | 98%; 99% | 1kg；10kg; 25kg | Career Henan Chemical Co |
-
- Cyclobutylmethylamine hydrochloride
5454-82-0
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- Cyclobutylmethylamine hydrochloride
5454-82-0
- $0.01
- 98%; 99%
- Career Henan Chemical Co
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